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LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL

Authors: Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Boerries, Francesco Pampaloni, Sjoerd J L van Wijk

Journal: Cell Death Dis

PubMed ID: 38245534

Doi: 10.1038/s41419-024-06447-6

Age-Dependent and Aβ-Induced Dynamic Changes in the Subcellular Localization of HMGB1 in Neurons and Microglia in the Brains of an Animal Model of Alzheimer's Disease

Authors: Song-I Seol, Dashdulam Davaanyam, Sang-A Oh, Eun-Hwa Lee, Pyung-Lim Han, Seung-Woo Kim, Ja-Kyeong Lee

Journal: Cells

PubMed ID: 38247880

Doi: 10.3390/cells13020189

Products & Services: PCR Cloning and Subcloning

Combined Immunoinformatics to Design and Evaluate a Multi-Epitope Vaccine Candidate against Infection

Authors: Song Liang, Shidan Zhang, Yinli Bao, Yumin Zhang, Xinyi Liu, Huochun Yao, Guangjin Liu

Journal: Vaccines (Basel)

PubMed ID: 38400121

Doi: 10.3390/vaccines12020137

Products & Services: Catalog Antibodies

Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar ()

Authors: Paolo Valentini, Srinivas Akula, Abigail Alvarado-Vazquez, Jenny Hallgren, Zhirong Fu, Brett Racicot, Ingo Braasch, Michael Thorpe, Lars Hellman

Journal: Int J Mol Sci

PubMed ID: 38338947

Doi: 10.3390/ijms25031669

Products & Services: Molecular Biology Reagents

Knock-in mutagenesis in Drosophila Rdl underscores the critical role of the conserved M3 glycine in mediating the actions of broflanilide and isocycloseram on GABA receptors

Authors: Yoshihisa Ozoe, Toshifumi Nakao, Shu Kondo, Yasuhide Yoshioka, Fumiyo Ozoe, Shinichi Banba

Journal: Pestic Biochem Physiol

PubMed ID: 38458683

Doi: 10.1016/j.pestbp.2024.105776

Products & Services: Gene Synthesis

Screening and Identification of Anti-Idiotypic Nanobody Capable of Broad-Spectrum Recognition of the Toxin Binding Region of Lepidopteran Cadherins and Mimicking Domain II of Cry2Aa Toxin

Authors: Cheng Shen, Jiafeng Jin, Ziyan Huang, Meng Meng, Manman Lin, Xiaodan Hu, Qing Zhu, Chongxin Xu, Wei Chen, Johnson Lin, Xiao Zhang, Yuan Liu, Xianjin Liu

Journal: J Agric Food Chem

PubMed ID: 38221880

Doi: 10.1021/acs.jafc.3c07295

Products & Services: Molecular Biology Reagents

USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication

Authors: Hannah L Mackay, Helen R Stone, Katherine Ellis, George E Ronson, Alexandra K Walker, Katarzyna Starowicz, Alexander J Garvin, Patrick van Eijk, Alina Vaitsiankova, Sobana Vijayendran, James F Beesley, Eva Petermann, Eric J Brown, Ruth M Densham, Simon H Reed, Felix Dobbs, Marco Saponaro, Joanna R Morris

Journal: biorxiv

PubMed ID: 38260523

Doi: 10.1101/2024.01.10.574674

Products & Services: Molecular Biology Reagents

Glucose 6-phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production

Authors: Sri Harsha Adusumilli, Anuthariq Alikkam Veetil, Chinmayee Choudhury, Banani Chattopadhyaya, Diptimayee Behera, Anand Kumar Bachhawat

Journal: FEBS Open Bio

PubMed ID: 38124687

Doi: 10.1002/2211-5463.13755

Products & Services: Molecular Biology Reagents

Jianpi Antai formula prevents miscarriage by repressing M1 polarization of decidual macrophages through ubiquitination of NLRP3 mediated by MARCH7

Authors: Ying Zhao, Chenyun Miao, Ruye Wang, Yun Chen, Ning Ren, Jing Ma, Tao Gao, Qin Zhang

Journal: J Ethnopharmacol

PubMed ID: 38246482

Doi: 10.1016/j.jep.2024.117796

Products & Services: Protein Electrophoresis and Western

A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy

Authors: Maryamsadat Seyedsadr, Madison Bang, Ethan McCarthy, Shirley Zhang, Ho-Chung Chen, Mahnia Mohebbi, Willy Hugo, Jason K Whitmire, Melissa G Lechner, Maureen A Su

Journal: biorxiv

PubMed ID: 38260637

Doi: 10.1101/2024.01.07.574553

Products & Services: ORF cDNA Clones/MolecularCloud