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Sudden death-associated KCNH2 variants exert opposing effects on a nuclear subdomain of the cardiac potassium channel hERG1

Authors: Francisco G Sanchez-Conde, Matthew R Goodrich, Olivia M Stack, Louis N R Goldberg, Pamela K Ruzycki, Abhilasha Jain, Eric N Jimenez-Vazquez, David K Jones

Journal: Molecular Therapy

PubMed ID: 41708004

Doi: 10.1016/j.jbc.2026.111296

Products & Services: Mutagenesis Services

AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPKMTOR-autophagy pathway in macrophage

Authors: Rui Chao, Lei Sun, Xinyu Xu, Zhan Liu, Xinyi Xu, Zhen Ren, Xinwei Chen, Weifeng Xu, Xuzhuo Chen, Ying Hu, Shanyong Zhang

Journal: Journal of nanobiotechnology

PubMed ID: 41634773

Doi: 10.1186/s12951-026-04080-3

Products & Services: Protein Electrophoresis and Western

Genome-Wide Identification, Characterization, Expression Analysis, and Interacting Protein Prediction of the GSK3/Shaggy-like Gene Family in Watermelon

Authors: Peng Tian, Jingjing Zhang, Bowen Liu, Xiurui Gao, Bing Li, Wei Liu and Yanrong Wu

Journal: Plants-Basel

Doi: 10.3390/plants15030484

Products & Services: Gene Synthesis

Unified modeling of 3D molecular generation via atomic interactions with PocketXMol

Authors: Xingang Peng, Ruihan Guo, Fenglin Guo, Ziyi Wang, Jiayu Sun, Jiaqi Guan, Yinjun Jia, Yan Xu, Yanwen Huang, Muhan Zhang, Jian Peng, Xinquan Wang, Chuanhui Han, Zihua Wang, Jianzhu Ma

Journal: Cell

PubMed ID: 41713417

Doi: 10.1016/j.cell.2026.01.003

Products & Services: Peptide Synthesis

Precise and efficient DNA base editing restores normal hearing in adult DFNB9 mouse model

Authors: Ziyu Zhang, Man Wang, Fangzhi Tan, Liyan Zhang, Xiaohan Wang, Xiangyan Chen, Jia Han, Nianci Li, Qiuhan Sun, Yicheng Lu, Zhiping Cui, Zuhong He, Jieyu Qi, Renjie Chai

Journal: Med

PubMed ID: 41763223

Doi: 10.1016/j.medj.2026.101001

Products & Services: Protein Electrophoresis and Western

Systematic analysis of functional genetic and epigenetic variants in colorectal cancer

Authors: Erfei Chen, Qiqi Yang, Haoyang Dai, Yixin Chen, Yihui Zhang, Qianglong Wang, Rongrong Hou, Ming Chen, Jie Wang, Qianwen Xie, Wenju Sun, Yong-Qiang Ning, Ligang Fan, Jian Yan

Journal: SCIENCE ADVANCES

PubMed ID: 41719390

Doi: https://doi.org/10.1126/sciadv.aeb2473

Products & Services: NGS Oligos

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Authors: Lyuba Y Salih, Nicolas L A Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P Moritz, Yannick Tholance, Jean-Philippe Camdessanché, Jean-Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François-Moutal, Aubin Moutal

Journal: Advanced Science

PubMed ID: 41700748

Doi: 10.1002/advs.202511413

A novel two-component system regulates shikimate pathway for thermal adaptation in Thermus thermophilus

Authors: Xuying Bu, Yuwen Guo, Xiangyu Tian, Yuan Shao, Changyou Li, Pan Zhang, Yunxiang Liang, Yingjun Li

Journal: Nucleic Acids Research

PubMed ID: 41693563

Doi: 10.1093/nar/gkag116

Products & Services: Protein and Antibody Isolation

MicroRNA-375-3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Authors: Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li

Journal: Advanced Science