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Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays

Authors: Andrew Santiago-Frangos, William S Henriques, Tanner Wiegand, Colin C Gauvin, Murat Buyukyoruk, Ava B Graham, Royce A Wilkinson, Lenny Triem, Kasahun Neselu, Edward T Eng, Gabriel C Lander, Blake Wiedenheft

Journal: Nat Struct Mol Biol

PubMed ID: 37710013

Doi: 10.1038/s41594-023-01097-2

Products & Services: DNA Sequencing

Ser14 phosphorylation of Bcl-xL mediates compensatory cardiac hypertrophy in male mice

Authors: Michinari Nakamura, Mariko Aoyagi Keller, Nadezhda Fefelova, Peiyong Zhai, Tong Liu, Yimin Tian, Shohei Ikeda, Dominic P Del Re, Hong Li, Lai-Hua Xie, Junichi Sadoshima

Journal: Nat Commun

PubMed ID: 37726310

Doi: 10.1038/s41467-023-41595-x

Products & Services: Peptide Synthesis

Gonacin: A germ cell-derived hormone with glucogenic, orexigenic, and gonadal activities

Authors: Yixuan Hu, Shengyou Zhao, Zhiquan Liu, Tao Kang, Aaron J W Hsueh, Jianzhen Li

Journal: iScience

PubMed ID: 37860761

Doi: 10.1016/j.isci.2023.108065

Products & Services: Recombinant Antibody Expression

A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization

Authors: Hannah E Gering , Xiaojun Li , Haoyu Tang , Paul D Swartz , Wei-Chen Chang , Thomas M Makris

Journal: J Am Chem Soc .

PubMed ID: 37611404

Doi: 10.1021/jacs.3c04542

Products & Services: Gene Synthesis

A CRISPRCas12a-SERS platform for amplification-free detection of African swine fever virus genes

Authors: Huimin Wang , Ailing Su , Chengxin Bao , Chongyang Liang , Weiqing Xu , Jingjing Chang , Shuping Xu

Journal: Talanta .

PubMed ID: 37741267

Doi: 10.1016/j.talanta.2023.125225

Products & Services: Synthetic Guide RNA

Engineered domain-inlaid Nme2Cas9 adenine base editors with increased on-target DNA editing and targeting scope

Authors: Ding Zhao , Xun Gao , Jiale Zhou , Jinze Li , Yuqiang Qian , Di Wang , Wenchao Niu , Tao Zhang , Mingyang Hu , Haoyang Xiong , Liangxue Lai , Zhanjun Li

Journal: BMC Biol .

PubMed ID: 37946200

Doi: 10.1186/s12915-023-01754-4

Products & Services: Gene Synthesis

Metasurface-Driven and Nanomaterial-Coupled Plasmonic Biosensor for the Rapid and Quantitative Clinical Identification of Neutralizing Antibodies against SARS-CoV-2 Variants

Authors: Rui Li, Ya Zhao, Hongli Fan, Hanlin Zhou, Shaoping Yin, Qiang Zhang, Meilin Jin,Gang L. Liu,and Liping Huang

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.202306145

Products & Services: Gene Synthesis

Comparative study between virus neutralisation testing and other serological methods detecting anti-SARS-CoV-2 antibodies in Europe, 2021

Authors: Ramona Mögling, Johan Reimerink, Kamelia R Stanoeva, Maria Keramarou, Raquel Guiomar, Inês Costa, Anu Haveri, Barbara Holzer, Gülay Korukluoğlu, Trung Nguyen, Gatis Pakarna, Katarzyna Pancer, Katarina Prosenc Trilar, Jelena Protic, Marijana Stojanović, Riccardo De Santis, Florigio Lista, Teodora Vremera, Mihaela Leustean, Adriana Pistol, Hana Zelena, Chantal Reusken, Eeva K Broberg

Journal: J Virol Methods

PubMed ID: 37778539

Doi: 10.1016/j.jviromet.2023.114825

Products & Services: Monoclonal Antibody Services

CWHM-974 is a fluphenazine derivative with improved antifungal activity against due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms

Authors: Aracely Miron-Ocampo, Sarah R Beattie, Soumitra Guin, Thomas Conway, Marvin J Meyers, W Scott Moye-Rowley, Damian J Krysan

Journal: Antimicrob Agents Chemother

PubMed ID: 37702508

Doi: 10.1128/aac.00567-23

Products & Services: Recombinant Proteins

Engineering conjugative CRISPR-Cas9 systems for the targeted control of enteric pathogens and antibiotic resistance

Authors: Haiqing Sheng, Sarah Wu, Yansong Xue, Wei Zhao, Allan B Caplan, Carolyn J Hovde, Scott A Minnich

Journal: PLoS ONE

PubMed ID: 37699034

Doi: 10.1371/journal.pone.0291520

Products & Services: Synthetic Guide RNA