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A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses

Authors: Sneha Vishwanath, George William Carnell, Matteo Ferrari, Benedikt Asbach, Martina Billmeier, Charlotte George, Maria Suau Sans, Angalee Nadesalingam, Chloe Qingzhou Huang, Minna Paloniemi, Hazel Stewart, Andrew Chan, David Arthur Wells, Patrick Neckermann, David Peterhoff, Sebastian Einhauser, Diego Cantoni, Martin Mayora Neto, Ingo Jordan, Volker Sandig, Paul Tonks, Nigel Temperton, Simon Frost, Katharina Sohr, Maria Teresa Lluesma Ballesteros, Farzad Arbabi, Johannes Geiger, Christian Dohmen, Christian Plank, Rebecca Kinsley, Ralf Wagner, Jonathan Luke Heeney

Journal: Nat Biomed Eng

PubMed ID: 37749309

Doi: 10.1038/s41551-023-01094-2

Products & Services: Protein and Antibody Isolation

A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences

Authors: Emily R Hildebrandt, Anushka Sarkar, Rajani Ravishankar, June H Kim, Walter K Schmidt

Journal: biorxiv

PubMed ID: 37786692

Doi: 10.1101/2023.09.19.558494

Products & Services: Protein and Antibody Isolation

Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II

Authors: David Flores-Solis, Irina P Lushpinskaia, Anton A Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M Pietrek, Patrick Cramer, Lukas S Stelzl, Bojan Zagrovic, Markus Zweckstetter

Journal: Nat Commun

PubMed ID: 37749095

Doi: 10.1038/s41467-023-41633-8

Products & Services: Protein and Antibody Isolation

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

Authors: Burcu Bestas, Sandra Wimberger, Dmitrii Degtev, Alexandra Madsen, Antje K Rottner, Fredrik Karlsson, Sergey Naumenko, Megan Callahan, Julia Liz Touza, Margherita Francescatto, Carl Ivar Möller, Lukas Badertscher, Songyuan Li, Silvia Cerboni, Niklas Selfjord, Elke Ericson, Euan Gordon, Mike Firth, Krzysztof Chylinski, Amir Taheri-Ghahfarokhi, Mohammad Bohlooly-Y, Mike Snowden, Menelaos Pangalos, Barrett Nuttall, Pinar Akcakaya, Grzegorz Sienski, Marcello Maresca

Journal: Nat Commun

PubMed ID: 37673883

Doi: 10.1038/s41467-023-41240-7

Products & Services: Protein and Antibody Isolation

One-step production of fully biotinylated and glycosylated human Fc gamma receptors

Authors: Minhyo Kang, Zening Wang, Xin Ge

Journal: Biotechnol Prog

PubMed ID: 37734055

Doi: 10.1002/btpr.3392

Products & Services: Protein and Antibody Isolation

Host Interactions with Engineered T-cell Micropharmacies

Authors: Christopher M Bourne, Patrick Wallisch, Megan M Dacek, Thomas J Gardner, Stephanie Pierre, Kristen Vogt, Broderick C Corless, Mamadou A Bah, Jesus E Romero-Pichardo, Angel Charles, Keifer G Kurtz, Derek S Tan, David A Scheinberg

Journal: Cancer Immunol Res

PubMed ID: 37379366

Doi: 10.1158/2326-6066.CIR-22-0879

Products & Services: Molecular Biology Reagents

PAR4 Inhibition Reduces Coronary Artery Atherosclerosis and Myocardial Fibrosis in SR-B1/LDLR Double Knockout Mice

Authors: Samuel K Lee, Rida A Malik, Ji Zhou, Wei Wang, Peter L Gross, Jeffrey I Weitz, Rithwik Ramachandran, Bernardo L Trigatti

Journal: Arterioscler Thromb Vasc Biol

PubMed ID: 37675637

Doi: 10.1161/ATVBAHA.123.319767

Products & Services: Molecular Biology Reagents

CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c-Raf/p-MEK/p-ERK signaling loop

Authors: Xiujuan Zhang, Yu Zhao, Ruzetuoheti Yiminniyaze, Ning Zhu, Yuanyuan Zhang, Gulinuer Wumaier, Jingwen Xia, Liang Dong, Daibing Zhou, Jing Wang, Chengwei Li, Youzhi Zhang, Shengqing Li

Journal: Mol Carcinog

PubMed ID: 37737453

Doi: 10.1002/mc.23636

Products & Services: Molecular Biology Reagents

Nanopore sequencing of DNA-barcoded probes for highly multiplexed detection of microRNA, proteins and small biomarkers

Authors: Caroline Koch, Benedict Reilly-O'Donnell, Richard Gutierrez, Carla Lucarelli, Fu Siong Ng, Julia Gorelik, Aleksandar P Ivanov, Joshua B Edel

Journal: Nat Nanotechnol

PubMed ID: 37749222

Doi: 10.1038/s41565-023-01479-z

Products & Services: Peptide Synthesis

Oligomeric State of β-Coronavirus Non-Structural Protein 10 Stimulators Studied by Small Angle X-ray Scattering

Authors: Wolfgang Knecht, S Zoë Fisher, Jiaqi Lou, Céleste Sele, Shumeng Ma, Anna Andersson Rasmussen, Nikos Pinotsis, Frank Kozielski

Journal: Int J Mol Sci

PubMed ID: 37686452

Doi: 10.3390/ijms241713649

Products & Services: Nucleic Acid Purification