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Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Authors: Jason Z. Zhang, William H. Nguyen, Nathan Greenwood, John C. Rose, Shao-En Ong, Dustin J. Maly & David Baker

Journal: Nature Biotechnol

PubMed ID: 38228150

Doi: 10.1038/s41587-023-02107-w

Products & Services: Plasmid DNA Preparation

Structure-guided discovery of anti-CRISPR and anti-phage defense proteins

Authors: Ning Duan , Emily Hand , Mannuku Pheko , Shikha Sharma , Akintunde Emiola

Journal: Nat Commun

PubMed ID: 38245560

Doi: 10.1038/s41467-024-45068-7

Products & Services: Codon Optimization

Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques

Authors: Rajeshwer S Sankhala , Kerri G Lal , Jaime L Jensen , Vincent Dussupt , Letzibeth Mendez-Rivera , Hongjun Bai , Lindsay Wieczorek , Sandra V Mayer , Michelle Zemil , Danielle A Wagner , Samantha M Townsley , Agnes Hajduczki , William C Chang , Wei-Hung Chen , Gina C Donofrio , Ningbo Jian , Hannah A D King , Cynthia G Lorang , Elizabeth J Martinez , Phyllis A Rees , Caroline E Peterson , Fabian Schmidt , Tricia J Hart , Debra K Duso , Lawrence W Kummer , Sean P Casey , Jazmean K Williams , Shruthi Kannan , Bonnie M Slike , Lauren Smith , Isabella Swafford , Paul V Thomas , Ursula Tran , Jeffrey R Currier , Diane L Bolton , Edgar Davidson , Benjamin J Doranz , Theodora Hatziioannou , Paul D Bieniasz , Dominic Paquin-Proulx , William W Reiley , Morgane Rolland , Nancy J Sullivan , Sandhya Vasan , Natalie D Collins , Kayvon Modjarrad , Gregory D Gromowski , Victoria R Polonis , Nelson L Michael , Shelly J Krebs , M Gordon Joyce

Journal: Nat Commun

PubMed ID: 38172512

Doi: 10.1038/s41467-023-44265-0.

Products & Services: Antibody Modification and Purification Services

Therapeutic vaccination with lentiviral vector in HBV-persistent mice and two inactive HBsAg carriers

Authors: Yumeng Zhang, Maryline Bourgine , Yanmin Wan, Jieyu Song, Zongying Li, Yiqi Yu, Wangfang Jiang, Mingzhe Zhou, Cuiyuan Guo, Didier Santucci, Xiao Liang, Christian Brechot, Wenhong Zhang, Pierre Charneau, Hong Wu, Chao Qiu

Journal: Hepatology

PubMed ID: 37827470

Doi: 10.1016/j.jhep.2023.09.019

Products & Services: Peptide Synthesis

Increasing β-hexosaminidase A activity using genetically modified mesenchymal stem cells

Authors: Alisa A Shaimardanova , Daria S Chulpanova , Valeriya V Solovyeva 1, Shaza S Issa , Aysilu I Mullagulova , Angelina A Titova , Yana O Mukhamedshina , Anna V Timofeeva , Alexander M Aimaletdinov , Islam R Nigmetzyanov , Albert A Rizvanov

Journal: Neural Regen Res .

PubMed ID: 37488869

Doi: 10.4103/1673-5374.375328

Products & Services: Gene Synthesis

Role of Histiocyte-Derived frHMGB1 as a Facilitator in Non-Canonical Pyroptosis of Monocytes/Macrophages in Lethal Sepsis

Authors: Yu Tian, Yuwen Cao, Fang Liu, Lin Xia, Chao Wang, Zhaoliang Su

Journal: J Infect Dis

PubMed ID: 38243905

Doi: 10.1093/infdis/jiae020

Products & Services: Molecular Biology Reagents

Recombinant T7 RNA polymerase production using ClearColi BL21(DE3) and animal-free media for in vitro transcription

Authors: Qianying Liang, Bowen Tu, Lun Cui

Journal: Appl Microbiol Biotechnol

PubMed ID: 38180552

Doi: 10.1007/s00253-023-12939-w

Products & Services: Molecular Biology Reagents

Chimeric proteins of Mycoplasma hyopneumoniae as vaccine and preclinical model for immunological evaluation

Authors: Marcus Rebouças Santos, Leonardo Teófilo Toledo, Ênio José Bassi, Wagnner José Nascimento Porto, Gustavo Costa Bressan, Maria Aparecida S Moreira, Yung-Fu Chang, Abelardo Silva-Júnior

Journal: Braz J Microbiol

PubMed ID: 38217795

Doi: 10.1007/s42770-023-01240-7

Products & Services: Protein and Antibody Isolation

Electrically silent KvS subunits associate with native Kv2 channels in brain and impact diverse properties of channel function

Authors: Michael Ferns, Deborah van der List, Nicholas C Vierra, Taylor Lacey, Karl Murray, Michael Kirmiz, Robert G Stewart, Jon T Sack, James S Trimmer

Journal: biorxiv

PubMed ID: 38328147

Doi: 10.1101/2024.01.25.577135

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Glyoxylate reductase: Definitive identification in human liver mitochondria, its importance for the compartment-specific detoxification of glyoxylate

Authors: Sander F Garrelfs, Serhii Chornyi, Heleen Te Brinke, Jos Ruiter, Jaap Groothoff, Ronald J A Wanders

Journal: J Inherit Metab Dis

PubMed ID: 38200664

Doi: 10.1002/jimd.12711

Products & Services: Gene Synthesis