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Genistein alleviates chronic heat stress-induced lipid metabolism disorder and mitochondrial energetic dysfunction by activating the GPR30-AMPK-PGC-1α signaling pathways in the livers of broiler chickens

Authors: Longlong Li, Ze Lu, Yulei Wang, Ying Yang, Huihui Wang, Haitian Ma

Journal: Poult Sci

PubMed ID: 37984004

Doi: 10.1016/j.psj.2023.103251

Products & Services: Protein and Antibody Isolation

Condensation of the N-terminal domain of human topoisomerase 1 is driven by electrostatic interactions and tuned by its charge distribution

Authors: Greta Bianchi, Marco Mangiagalli, Diletta Ami, Junaid Ahmed, Silvia Lombardi, Sonia Longhi, Antonino Natalello, Peter Tompa, Stefania Brocca

Journal: Int J Biol Macromol

PubMed ID: 38287572

Doi: 10.1016/j.ijbiomac.2023.127754

Products & Services: Protein and Antibody Isolation

Cell-Permeable Stimuli-Responsive Ubiquitin Probe for Time- Resolved Monitoring of Substrate Ubiquitination in Live Cells

Authors: Lu-Jun Liang, Yu Wang, Xiao Hua, Rujing Yuan, Qiong Xia, Rongtian Wang, Chuntong Li, Guo-Chao Chu, Lei Liu, and Yi-Ming Li

Journal: JACS Au

Doi: 10.1021/jacsau.3c00421

Products & Services: Gene Synthesis

A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering

Authors: Zhiheng Yang , Zilong Li , Bixiao Li , Ruihong Bu , Gao-Yi Tan , Zhengduo Wang , Hao Yan , Zhenguo Xin , Guojian Zhang , Ming Li , Hua Xiang, Lixin Zhang , Weishan Wang

Journal: Nat Commun .

PubMed ID: 37794017

Doi: 10.1038/s41467-023-41973-5

Products & Services: Custom DNA/RNA Oligos CRISPR Libraries

A 3D-printed blood-brain barrier model with tunable topology and cell-matrix interactions

Authors: Louis S Paone , Mohammed Mehdi Benmassaoud , Aidan Curran , Sebastián L Vega , Peter A Galie

Journal: Biofabrication .

PubMed ID: 37820611

Doi: 10.1088/1758-5090/ad0260

Products & Services: Peptide Synthesis

Molecular insights into the HLA-B35 molecules' classification associated with HIV control

Authors: Christian A Lobos, Demetra Sm Chatzileontiadou, Bonin Sok, Coral-Ann Almedia, Hanim Halim, Lloyd D'Orsogna, Stephanie Gras

Journal: Immunol Cell Biol

PubMed ID: 37811811

Doi: 10.1111/imcb.12698

Products & Services: Peptide Synthesis

Intervention of AXL in EGFR Signaling via Phosphorylation and Stabilization of MIG6 in Non-Small Cell Lung Cancer

Authors: Ya-Yu Yang, Sheng-Chieh Lin, Jong-Ding Lay, Chun-Yu Cho, Te-Hsuan Jang, Hsiu-Ying Ku, Chih-Jung Yao, Shuang-En Chuang

Journal: Int J Mol Sci

PubMed ID: 37834326

Doi: 10.3390/ijms241914879

Products & Services: Protein and Antibody Isolation

Unfolding of an RNA G-quadruplex motif in the negative strand genome of porcine reproductive and respiratory syndrome virus by host and viral helicases to promote viral replication

Authors: Puxian Fang, Congbao Xie, Ting Pan, Ting Cheng, Wei Chen, Sijin Xia, Tong Ding, Junkang Fang, Yanrong Zhou, Liurong Fang, Dengguo Wei, Shaobo Xiao

Journal: Nucleic Acids Res

PubMed ID: 37739415

Doi: 10.1093/nar/gkad759

Products & Services: Protein and Antibody Isolation

Dual immunization with CdtB protein and flagellin epitope offers augmented protection against enteric fever in mice

Authors: Shania Vij, Reena Thakur, Raghwendra Pratap Singh, Rashmi Kumar, Preeti Pathania, Varsha Gupta, Chander Raman Suri, Praveen Rishi

Journal: Life Sci

PubMed ID: 37918629

Doi: 10.1016/j.lfs.2023.122216

Products & Services: Custom RNAi Services

Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury

Authors: Liushenyan Yu, Junchao Xue, Yanyan Wu, Hanyu Zhou