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FGFR1 expression correlates inversely with the efficacy of single-agent FGFR-specific inhibitors in pancreatic cancer

Authors: Qingxiang Lin, Andrea Serratore, Jonathan Perri, Tista Roy Chaudhuri, Jun Qu, Wen Wee Ma, Eugene Kandel, Robert M Straubinger

Journal: Br J Pharmacol

PubMed ID: 37994108

Doi: 10.1111/bph.16289

Products & Services: Custom Vector Construction

Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis

Authors: Hana Lastuvkova, Zuzana Nova, Milos Hroch, Fatemeh Alaei Faradonbeh, Jolana Schreiberova, Jaroslav Mokry, Hana Faistova, Alzbeta Stefela, Jan Dusek, Otto Kucera, Radomír Hyspler, Ester Dohnalkova, Rachel L Bayer, Petra Hirsova, Petr Pavek, Stanislav Micuda

Journal: Toxicol Sci

PubMed ID: 37632784

Doi: 10.1093/toxsci/kfad088

Products & Services: Molecular Biology Reagents

Using for high-yield production of challenging expression targets and for protein deuteration

Authors: Natalia Mojica, Flore Kersten, Mateu Montserrat-Canals, G Robb Huhn, Abelone M Tislevoll, Gabriele Cordara, Ken Teter, Ute Krengel

Journal: biorxiv

PubMed ID: 37961550

Doi: 10.1101/2023.11.03.565449

Products & Services: Molecular Biology Reagents

Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs

Authors: Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, David Groff, Wei Li, Moreno di Marco, Erin Runbeck, Hau Truong, Jugmohit S Toor, Sarvind Tripathi, Son Nguyen, Helena Shen, Tiffany Noel, Nicole L Church, Amber Weiner, Nathan Kendsersky, Dan Martinez, Rebecca Weisberg, Molly Christie, Laurence Eisenlohr, Kristopher R Bosse, Dimiter S Dimitrov, Stefan Stevanovic, Nikolaos G Sgourakis, Ben R Kiefel, John M Maris

Journal: Nature

PubMed ID: 37938785

Doi: 10.1038/s41586-023-06731-z

Products & Services: Peptide Synthesis

Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants

Authors: Shudan Tan, Jinghua Zhao, Xue Hu, Yufeng Li, Zihan Wu, Guoliang Lu, Zhaoli Yu, Binhe Du, Yan Liu, Li Li, Yuchen Chen, Ye Li, Yanfeng Yao, Xiaoyu Zhang, Juhong Rao, Ge Gao, Yun Peng, Hang Liu, Zhiming Yuan, Jia Liu, Qianran Wang, Hengrui Hu, Xiaobo Gao, Hui Zhou, Hang Yu, Yingjie Xu, Wei Yu, Lin Feng, Manli Wang, Chao Shan, Jing Lu, Jinzhong Lin

Journal: Sci Bull (Beijing)

PubMed ID: 37993332

Doi: 10.1016/j.scib.2023.11.024

Products & Services: Plasmids for SARS-CoV-2 Detection and Research

O-Linked N-Acetylglucosamine Transferase Regulates Bone Homeostasis Through Alkaline Phosphatase Pathway in Diabetic Periodontitis

Authors: Wei Luo, Lu Sun

Journal: Mol Biotechnol

PubMed ID: 37951846

Doi: 10.1007/s12033-023-00947-0

Products & Services: Protein and Antibody Isolation

Multiple highly expressed phosphoenolpyruvate carboxylase genes have divergent enzyme kinetic properties in two C4 grasses

Authors: Robert J DiMario, Ashley N Kophs, Anthony J A Apalla, James N Schnable, Asaph B Cousins

Journal: Ann Bot

PubMed ID: 37675505

Doi: 10.1093/aob/mcad116

Products & Services: Protein and Antibody Isolation

Transcriptomic analyses reveal proinflammatory activation of human brain microvascular endothelial cells by aging-associated peptide medin and reversal by nanoliposomes

Authors: Yining Zhang, Nina Karamanova, Kaleb T Morrow, Jillian Madine, Seth Truran, Maria Lozoya, Volkmar Weissig, Ming Li, Mehdi Nikkhah, Jin G Park, Raymond Q Migrino

Journal: Sci Rep

PubMed ID: 37914766

Doi: 10.1038/s41598-023-45959-7

Products & Services: Protein and Antibody Isolation

SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer

Authors: Xiayao Diao, Chao Guo, Hanhao Zheng, Ke Zhao, Yuming Luo, Mingjie An, Yan Lin, Jiancheng Chen, Yuanlong Li, Yuting Li, Xuehan Gao, Jiaqi Zhang, Mengxin Zhou, Wenliang Bai, Lei Liu, Guige Wang, Lanjun Zhang, Xiaotian He, Rusi Zhang, Zhihua Li, Changhao Chen, Shanqing Li

Journal: Signal Transduct Target Ther

PubMed ID: 37925421

Doi: 10.1038/s41392-023-01685-0

Products & Services: Gene Synthesis

A Novel mechanism of herbicide action through disruption of pyrimidine biosynthesis

Authors: Il-Ho Kang, Ryan P Emptage, Sang-Ic Kim, Steven Gutteridge

Journal: Proc Natl Acad Sci U S A

PubMed ID: 37988466

Doi: 10.1073/pnas.2313197120

Products & Services: Protein and Antibody Isolation