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Development of a multi-epitope vaccine candidate for leishmanial parasites applying immunoinformatics and approaches

Authors: Rahila Qureshi, Insaf Ahmed Qureshi

Journal: Front Immunol

PubMed ID: 38035118

Doi: 10.3389/fimmu.2023.1269774

Products & Services: Molecular Biology Reagents

Telomerase Upregulation Induces Progression of Mouse BrafV600E-Driven Thyroid Cancers and Triggers Nontelomeric Effects

Authors: Iñigo Landa, Caitlin E M Thornton, Bin Xu, Jacob Haase, Gnana P Krishnamoorthy, Jingzhu Hao, Jeffrey A Knauf, Zachary T Herbert, Paula Martínez, María A Blasco, Ronald Ghossein, James A Fagin

Journal: Mol Cancer Res

PubMed ID: 37478162

Doi: 10.1158/1541-7786.MCR-23-0144

Products & Services: PCR Cloning and Subcloning

A glutamate-gated chloride channel as the mite-specific target-site of dicofol and other diphenylcarbinol acaricides

Authors: Marilou Vandenhole, Catherine Mermans, Berdien De Beer, Wenxin Xue, Yilan Zhao, Yoshihisa Ozoe, Genyan Liu, Wannes Dermauw, Thomas Van Leeuwen

Journal: Commun Biol

PubMed ID: 37957415

Doi: 10.1038/s42003-023-05488-5

Products & Services: Codon Optimization

A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease

Authors: Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand González-Escalante, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R Kac, Michael Turton, Hlin Kvartsberg, Nicholas J Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Minguillon, Jose Contador, Marc Suárez-Calvet, Thomas K Karikari, Kaj Blennow

Journal: Alzheimers Dement

PubMed ID: 37975513

Doi: 10.1002/alz.13525

Engineered immunogens to elicit antibodies against conserved coronavirus epitopes

Authors: A Brenda Kapingidza, Daniel J Marston, Caitlin Harris, Daniel Wrapp, Kaitlyn Winters, Dieter Mielke, Lu Xiaozhi, Qi Yin, Andrew Foulger, Rob Parks, Maggie Barr, Amanda Newman, Alexandra Schäfer, Amanda Eaton, Justine Mae Flores, Austin Harner, Nicholas J Catanzaro, Michael L Mallory, Melissa D Mattocks, Christopher Beverly, Brianna Rhodes, Katayoun Mansouri, Elizabeth Van Itallie, Pranay Vure, Brooke Dunn, Taylor Keyes, Sherry Stanfield-Oakley, Christopher W Woods, Elizabeth A Petzold, Emmanuel B Walter, Kevin Wiehe, Robert J Edwards, David C Montefiori, Guido Ferrari, Ralph Baric, Derek W Cain, Kevin O Saunders, Barton F Haynes, Mihai L Azoitei

Journal: Nat Commun

PubMed ID: 38036525

Doi: 10.1038/s41467-023-43638-9

Products & Services: Protein and Antibody Isolation

Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity

Authors: Seounghun Kang, Aslan Mansurov, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Kevin Chang, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Jun Ishihara, Melody A Swartz, Jeffrey A Hubbell

Journal: Sci Adv

PubMed ID: 38019919

Doi: 10.1126/sciadv.adh9879

Products & Services: Protein and Antibody Isolation

Role and mechanism of miR-871-3p/Megf8 in regulating formaldehyde-induced cardiomyocyte inflammation and congenital heart disease

Authors: Xiaoli Yuan, Rui Chen, Gang Luo, Pin Sun, Xiaoxia Song, Jianmin Ma, Ruicong Sun, Tao Yu, Zhirong Jiang

Journal: Int Immunopharmacol

PubMed ID: 38039718

Doi: 10.1016/j.intimp.2023.111297

Products & Services: Protein and Antibody Isolation

Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus

Authors: So Jin Bing, Morten Seirup, Trish T Hoang, Susana S Najera, Collin Britten, Stephanee L Warrington, Shiang-Ling Chu, Ronit Mazor

Journal: Nat Biomed Eng

PubMed ID: 37996615

Doi: 10.1038/s41551-023-01129-8

Products & Services: Peptide Synthesis

DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones

Authors: Meital Abayev-Avraham, Yehuda Salzberg, Dar Gliksberg, Meital Oren-Suissa, Rina Rosenzweig

Journal: Nat Commun

PubMed ID: 37923706

Doi: 10.1038/s41467-023-42735-z

Products & Services: Protein and Antibody Isolation

Critical role of TPRN rings in the stereocilia for hearing

Authors: Jieyu Qi, Fangzhi Tan, Liyan Zhang, Yinyi Zhou, Ziyu Zhang, Qiuhan Sun, Nianci Li, Yuan Fang, Xin Chen, Yunhao Wu, Guisheng Zhong, Renjie Chai

Journal: Mol Ther

PubMed ID: 37952086

Doi: 10.1016/j.ymthe.2023.11.011

Products & Services: Protein and Antibody Isolation