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TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease

Authors: Yiyang Qin, Laiqiang Chen, Wenzhen Zhu, Jiahong Song, Jingpan Lin, Yuwei Li, Jiawei Zhang, Xichen Song, Tingting Xing, Tingting Guo, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Qi Wang, Bang Li, Weili Yang , Peng Yin, Xiao-Xin Yan, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: SCIENCE ADVANCES

PubMed ID: 38758800

Doi: 10.1126/sciadv.adl2036

Products & Services: Protein Electrophoresis and Western

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice

Authors: Laiqiang Chen, Yiyang Qin, Tingting Guo, Wenzhen Zhu, Jingpan Lin, Tingting Xing, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Xiang Li, Peng Yin, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: Cell Death Dis

PubMed ID: 38744826

Doi: 10.1038/s41419-024-06716-4

Products & Services: Protein Electrophoresis and Western

Type IX Collagen Turnover Is Altered in Patients with Solid Tumors

Authors: Helena Port, Yi He, Morten A Karsdal, Emilie A Madsen, Anne-Christine Bay-Jensen, Nicholas Willumsen, Signe Holm Nielsen

Journal: Cancers (Basel)

PubMed ID: 38893155

Doi: 10.3390/cancers16112035

Products & Services: Catalog Antibodies

AAV-mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration

Authors: Liyan Zhang, Xin Chen, Xinlin Wang, Yinyi Zhou, Yuan Fang, Xingliang Gu, Ziyu Zhang, Qiuhan Sun, Nianci Li, Lei Xu, Fangzhi Tan, Renjie Chai, Jieyu Qi

Journal: Adv Sci (Weinh)

PubMed ID: 38810137

Doi: 10.1002/advs.202304551

Products & Services: Protein and Antibody Isolation

Development of a Fully Protective Pandemic Avian Influenza Subunit Vaccine in Insect Pupae

Authors: Ana Falcón, Susana Martínez-Pulgarín, Sergi López-Serrano, Edel Reytor, Miguel Cid, Maria Del Carmen Nuñez, Lorena Córdoba, Ayub Darji, José M Escribano

Journal: Viruses

PubMed ID: 38932122

Doi: 10.3390/v16060829

Products & Services: Gene Synthesis

A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction

Authors: Baiyang Sun, Zihe Liang, Yupeng Wang, Yue Yu, Xiaobing Zhou, Xingchao Geng, Bo Li

Journal: Toxicology

PubMed ID: 38740170

Doi: 10.1016/j.tox.2024.153829

Products & Services: Protein and Antibody Isolation

In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

Authors: Melisa Benard-Valle, Yessica Wouters, Anne Ljungars, Giang Thi Tuyet Nguyen, Shirin Ahmadi, Tasja Wainani Ebersole, Camilla Holst Dahl, Alid Guadarrama-Martínez, Frederikke Jeppesen, Helena Eriksen, Gibran Rodríguez-Barrera, Kim Boddum, Timothy Patrick Jenkins, Sara Petersen Bjørn, Sanne Schoffelen, Bjørn Gunnar Voldborg, Alejandro Alagón & Andreas Hougaard Laustsen

Journal: Nat Commun

PubMed ID: 38773068

Doi: 10.1038/s41467-024-48539-z

Products & Services: Gene Synthesis

Nuclear Magnetic Resonance based fragment screen of the E3 ligase Fem 1 homolog B

Authors: Jade M. Katinas; Kangsa Amporndanai; Ashley J. Taylor; Kristie L. Rose; Peter C. Gareiss; Roberto A. Crespo; Jason Phan; Alex G. Waterson; Stephen W. Fesik

Journal: Protein science : a publication of the Protein Society

PubMed ID: 41229306

Doi: 10.1002/pro.70365

Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extracts

Authors: Lisa Schmidt, Christian Tüting, Fotis L Kyrilis, Farzad Hamdi, Dmitry A Semchonok, Gerd Hause, Annette Meister, Christian Ihling, Milton T Stubbs, Andrea Sinz, Panagiotis L Kastritis

Journal: Commun Biol

PubMed ID: 38730276

Doi: 10.1038/s42003-024-06204-7

Products & Services: Catalog Peptides

Immunogenicity Analysis and Identification of Potential T-Cell Epitopes in C129R Protein of African Swine Fever Virus

Authors: Wenzhu Zhai, Ying Huang, Yuheng He, Yuanyuan Chu, Chunhao Tao, Zhongbao Pang, Zhen Wang, Hongfei Zhu, Hong Jia

Journal: Microorganisms

PubMed ID: 38930438

Doi: 10.3390/microorganisms12061056

Products & Services: Catalog Peptides