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Computational design of generalist cyclopropanases with stereodivergent selectivity

Authors: Zhuofan Shen; Mary G. Siriboe; Xinkun Ren; Thakshila Dayananda; Jermaine L. Jenkins; Sagar D. Khare; Rudi Fasan

Journal: Nature Communications

PubMed ID: 41587967

Doi: 10.1038/s41467-026-68327-1

Computational design of generalist cyclopropanases with stereodivergent selectivity

Authors: Zhuofan Shen; Mary G. Siriboe; Xinkun Ren; Thakshila Dayananda; Jermaine L. Jenkins; Sagar D. Khare; Rudi Fasan

Journal: Nature Communications

PubMed ID: 41587967

Doi: 10.1038/s41467-026-68327-1

Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics

Authors: Jiyun Zhu; Alexandria M. Kemp; Bala C. Chenna; Vivek Kumar; Andrew Rademacher; Sangho Yun; Arthur Laganowsky; Thomas D. Meek

Journal: ACS catalysis

PubMed ID: 39722883

Doi: 10.1021/acscatal.4c04695

Bioinformatic prediction and experimental validation of RiPP recognition elements

Authors: Kyle E. Shelton; Douglas A. Mitchell

Journal: Methods in enzymology

PubMed ID: 36682862

Doi: 10.1016/bs.mie.2022.08.050

Bioinformatic prediction and experimental validation of RiPP recognition elements

Authors: Kyle E. Shelton; Douglas A. Mitchell

Journal: Methods in enzymology

PubMed ID: 36682862

Doi: 10.1016/bs.mie.2022.08.050

Bioinformatic prediction and experimental validation of RiPP recognition elements

Authors: Kyle E. Shelton; Douglas A. Mitchell

Journal: Methods in enzymology

PubMed ID: 36682862

Doi: 10.1016/bs.mie.2022.08.050

Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics

Authors: Jiyun Zhu; Alexandria M. Kemp; Bala C. Chenna; Vivek Kumar; Andrew Rademacher; Sangho Yun; Arthur Laganowsky; Thomas D. Meek

Journal: ACS catalysis

PubMed ID: 39722883

Doi: 10.1021/acscatal.4c04695

Nuclear Magnetic Resonance based fragment screen of the E3 ligase Fem 1 homolog B

Authors: Jade M. Katinas; Kangsa Amporndanai; Ashley J. Taylor; Kristie L. Rose; Peter C. Gareiss; Roberto A. Crespo; Jason Phan; Alex G. Waterson; Stephen W. Fesik

Journal: Protein science : a publication of the Protein Society

PubMed ID: 41229306

Doi: 10.1002/pro.70365

Single-molecule assay guided crRNA optimization enhances specific microRNA detection by CRISPR-Cas12a

Authors: Kaizhao Chen, Wenjun Sun, Mingtian Zhong, Jiaqi Xie, Yongkun Huo, Xiuqi Lu, Ziting Chen, Bo Sun, Xingxu Huang, Xinjie Wang， Ming Liu , Xiaodong Ma, Peixiang Ma

Journal: Sensors and Actuators B: Chemical

Doi: 10.1016/j.snb.2024.135389

Products & Services: Protein Electrophoresis and Western

Novel enzymes for biodegradation of polycyclic aromatic hydrocarbons identified by metagenomics and functional analysis in short-term soil microcosm experiments

Authors: Kinga K Nagy, Kristóf Takács, Imre Németh, Bálint Varga, Vince Grolmusz, Mónika Molnár, Beáta G Vértessy

Journal: Sci Rep

PubMed ID: 38773163

Doi: 10.1038/s41598-024-61566-6

Products & Services: Gene Synthesis