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Lipid-Polymer Nanoparticles Mediate Compartmentalized Delivery of Cas9 and sgRNA for Glioblastoma Vasculature and Immune Reprogramming

Authors: Huaqing Zhang, Wenxin Jiang, Tingting Song, Mingjie Song, Shengyu Liu, Jianping Zhou, Hao Cheng, Yang Ding

Journal: Adv Sci (Weinh)

PubMed ID: 38923275

Doi: 10.1002/advs.202309314

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

CD147-K148me2-Driven Tumor Cell-Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis

Authors: Ke Wang, Xiaohong Chen, Peng Lin, Jiao Wu, Qiang Huang, Zhi-Nan Chen, Jiale Tian, Hao Wang, Ye Tian, Mingyan Shi, Meirui Qian, Bengang Hui, Yumeng Zhu, Ling Li, Rui Yao, Huijie Bian, Ping Zhu, Ruo Chen, Liang Chen

Journal: Adv Sci (Weinh)

PubMed ID: 38873823

Doi: 10.1002/advs.202400611

Products & Services: Recombinant Proteins

Functional diversity among cardiolipin binding sites on the mitochondrial ADP/ATP carrier

Authors: Nanami Senoo, Dinesh K Chinthapalli, Matthew G Baile, Vinaya K Golla, Bodhisattwa Saha, Abraham O Oluwole, Oluwaseun B Ogunbona, James A Saba, Teona Munteanu, Yllka Valdez, Kevin Whited, Macie S Sheridan, Dror Chorev, Nathan N Alder, Eric R May, Carol V Robinson, Steven M Claypool

Journal: EMBO J

PubMed ID: 38839991

Doi: 10.1038/s44318-024-00132-2

Products & Services: Protein and Antibody Isolation

Highly biased agonism for GPCR ligands via nanobody tethering

Authors: Shivani Sachdev, Brendan A Creemer, Thomas J Gardella, Ross W Cheloha

Journal: Nat Commun

PubMed ID: 38824166

Doi: 10.1038/s41467-024-49068-5.

Products & Services: Protein and Antibody Isolation PCR Cloning and Subcloning

A growth selection system for sucrose synthases (SuSy): design and test

Authors: Gonzalo N Bidart, Se Hyeuk, Tobias Benedikt Alter, Lei Yang, Ditte Hededam Welner

Journal: AMB Express

PubMed ID: 38865019

Doi: 10.1186/s13568-024-01727-y

Products & Services: Molecular Biology Reagents

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection

Authors: Asfia Sultana, Anupriya M Geethakumari, Zeyaul Islam, Prasanna R Kolatkar, Kabir H Biswas

Journal: Front Bioeng Biotechnol

PubMed ID: 38887615

Doi: 10.3389/fbioe.2024.1353479

Products & Services: Protein and Antibody Isolation

Next-generation nanovaccine induces durable immunity and protects against SARS-CoV-2

Authors: Kathleen A Ross, Sean Kelly, Kruttika S Phadke, Nathan Peroutka-Bigus, Olufemi Fasina, Alaric Siddoway, Surya K Mallapragada, Michael J Wannemuehler, Bryan H Bellaire, Balaji Narasimhan

Journal: Acta Biomater

PubMed ID: 38844193

Doi: 10.1016/j.actbio.2024.05.048

Products & Services: Molecular Biology Reagents

Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design

Authors: Manjeet Mukherjee, Philip J Day, Duncan Laverty, Juan A Bueren-Calabuig, Andrew J Woodhead, Charlotte Griffiths-Jones, Steve Hiscock, Charlotte East, Susan Boyd, Marc O'Reilly

Journal: Structure

PubMed ID: 38870939

Doi: 10.1016/j.str.2024.05.011

Products & Services: Custom Vector Construction

Repeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms

Authors: Patricia Ferrer, Andrea A Berry, Allison N Bucsan, Surendra K Prajapati, Karthik Krishnan, Michelle C Barbeau, David M Rickert, Sandra Mendoza Guerrero, Miho Usui, Yonas Abebe, Asha Patil, Sumana Chakravarty, Peter F Billingsley, Faith Pa'ahana-Brown, Kathy Strauss, Biraj Shrestha, Effie Nomicos, Gregory A Deye, B Kim Lee Sim, Stephen L Hoffman, Kim C Williamson, Kirsten E Lyke

Journal: Nat Commun

PubMed ID: 38890271

Doi: 10.1038/s41467-024-49041-2

Products & Services: Catalog Peptides

The generation of stable transgenic lines in the human-infective nematode Strongyloides stercoralis

Authors: Ruhi Patel, Astra S Bryant, Michelle L Castelletto, Breanna Walsh, Damia Akimori, Elissa A Hallem

Journal: G3 (Bethesda)

PubMed ID: 38839055

Doi: 10.1093/g3journal/jkae122

Products & Services: Molecular Biology Reagents