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Structural basis of Gabija anti-phage defence and viral immune evasion

Authors: Sadie P Antine, Alex G Johnson, Sarah E Mooney, Azita Leavitt, Megan L Mayer, Erez Yirmiya, Gil Amitai, Rotem Sorek, Philip J Kranzusch

Journal: Nature

PubMed ID: 37992757

Doi: 10.1038/s41586-023-06855-2

Products & Services: Gene Synthesis

A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover

Authors: David S Glass 1, Anat Bren 2, Elizabeth Vaisbourd 2, Avi Mayo 2, Uri Alon

Journal: Cell

PubMed ID: 38320549

Doi: 10.1016/j.cell.2024.01.024

Products & Services: Plasmid DNA Preparation

Sirtuin 3 is required for the dexmedetomidine-mediated alleviation of inflammation and oxidative stress in nephritis

Authors: Kai Lu , Xinlong Li , Jie Wu

Journal: Immunity

PubMed ID: 38270316

Doi: 10.1002/iid3.1135

Products & Services: Custom DNA/RNA Oligos

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Authors: Gisele Nishiguchi , Lauren G Mascibroda , Sarah M Young , Elizabeth A Caine , Sherif Abdelhamed , Jeffrey J Kooijman , Darcie J Miller , Sourav Das , Kevin McGowan , Anand Mayasundari , Zhe Shi , Juan M Barajas , Ryan Hiltenbrand , Anup Aggarwal , Yunchao Chang , Vibhor Mishra , Shilpa Narina , Melvin Thomas , Allister J Loughran , Ravi Kalathur , Kaiwen Yu , Suiping Zhou , Xusheng Wang , Anthony A High , Junmin Peng , Shondra M Pruett-Miller , Danette L Daniels , Marjeta Urh , Anang A Shelat , Charles G Mullighan , Kristin M Riching , Guido J R Zaman , Marcus Fischer , Jeffery M Klco , Zoran Rankovic

Journal: Nat Commun

PubMed ID: 38228616

Doi: 10.1038/s41467-024-44698-1

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PIEZO1 loss-of-function compound heterozygous mutations in the rare congenital human disorder Prune Belly Syndrome

Authors: Nathalia G Amado , Elena D Nosyreva , David Thompson , Thomas J Egeland , Osita W Ogujiofor , Michelle Yang , Alexandria N Fusco , Niccolo Passoni , Jeremy Mathews , Brandi Cantarel , Linda A Baker , Ruhma Syeda

Journal: Nat Commun

PubMed ID: 38184690

Doi: 10.1038/s41467-023-44594-0

Products & Services: PCR Cloning and Subcloning

A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential

Authors: Gregory H Bird , J J Patten , William Zavadoski , Nicole Barucci , Marina Godes , Benjamin M Moyer , Callum D Owen , Paul DaSilva-Jardine , Donna S Neuberg , Richard A Bowen , Robert A Davey , Loren D Walensky

Journal: Nat Commun

PubMed ID: 38177138

Doi: 10.1038/s41467-023-44361-1

Products & Services: Plasmid DNA Preparation

Massively parallel profiling of RNA-targeting CRISPR-Cas13d

Authors: Hung-Che Kuo , Joshua Prupes , Chia-Wei Chou , Ilya J Finkelstein

Journal: Nat Commun

PubMed ID: 37034598

Doi: 10.1101/2023.03.27.534188

Products & Services: Custom Vector Construction

Correlations of receptor desensitization of gain-of-function GABRB3 variants with clinical severity

Authors: Susan X N Lin, Philip K Ahring, Angelo Keramidas, Vivian W Y Liao, Rikke S Møller, Mary Chebib, Nathan L Absalom

Journal: Brain

PubMed ID: 37647766

Doi: 10.1093/brain/awad285

Products & Services: Plasmid DNA Preparation

9S1R nullomer peptide induces mitochondrial pathology, metabolic suppression, and enhanced immune cell infiltration, in triple-negative breast cancer mouse model

Authors: Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R Veerabhadraiah, Laura Bond, Matthew W Turner, Cheryl L Jorcyk, Greg Hampikian

Journal: Biomed Pharmacother

PubMed ID: 38118350

Doi: 10.1016/j.biopha.2023.115997.

Products & Services: Peptide Synthesis

Redox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α

Authors: Zuen Ren, Malindrie Dharmaratne, Huizhi Liang, Outhiriaradjou Benard, Miriam Morales-Gallego, Kimita Suyama, Viney Kumar, Atefeh Taherian Fard, Ameya S Kulkarni, Michael Prystowsky, Jessica C Mar, Larry Norton, Rachel B Hazan

Journal: Br J Cancer

PubMed ID: 38238426

Doi: 10.1038/s41416-023-02522-5

Products & Services: ORF cDNA Clones/MolecularCloud