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mA-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia

Authors: Yanchun Zhao, Yutong Zhou, Yu Qian, Wenwen Wei, Xiangjie Lin, Shihui Mao, Jie Sun, Jie Jin

Journal: Clin Transl Med

PubMed ID: 38572589

Doi: 10.1002/ctm2.1628

Products & Services: Protein and Antibody Isolation

OsATL32 ubiquitinates the reactive oxygen species-producing OsRac5-OsRbohB module to suppress rice immunity

Authors: Yuqing Yan, Hui Wang, Yan Bi, Jiajing Wang, Muhammad Noman, Dayong Li, Fengming Song

Journal: J Integr Plant Biol

PubMed ID: 38629772

Doi: 10.1111/jipb.13666

Products & Services: Protein and Antibody Isolation

Label-free detection of Aβ-42: a liquid crystal droplet approach for Alzheimer's disease diagnosis

Authors: Saumya Ranjan Pradhan, Ramadevi Suguru Pathinti, Ramesh Kandimalla, Krishnakanth Chithari, Madhava Rao Veeramalla N, Jayalakshmi Vallamkondu

Journal: RSC Adv

PubMed ID: 38628477

Doi: 10.1039/d4ra00615a

Products & Services: Protein and Antibody Isolation

Therapeutic application of circular RNA aptamers in a mouse model of psoriasis

Authors: Si-Kun Guo, Chu-Xiao Liu, Yi-Feng Xu, Xiao Wang, Fang Nan, Youkui Huang, Siqi Li, Shan Nan, Ling Li, Edo Kon, Chen Li, Meng-Yuan Wei, Rina Su, Jia Wei, Shiguang Peng, Nitay Ad-El, Jiaquan Liu, Dan Peer, Ting Chen, Li Yang, Ling-Ling Chen

Journal: Nat Biotechnol

PubMed ID: 38653797

Doi: 10.1038/s41587-024-02204-4

Products & Services: Protein and Antibody Isolation

An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin

Authors: Jake A Hill, Yvonne Nyathi, Sam Horrell, David von Stetten, Danny Axford, Robin L Owen, Godfrey S Beddard, Arwen R Pearson, Helen M Ginn, Briony A Yorke

Journal: Commun Chem

PubMed ID: 38600176

Doi: 10.1038/s42004-024-01163-w

Products & Services: Mutant Libraries

CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition

Authors: Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B Huppa, Sonia Guedan

Journal: Nat Commun

PubMed ID: 38670972

Doi: 10.1038/s41467-024-47799-z

Products & Services: Catalog Peptides

Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer's disease by inhibiting neuroinflammation and neuronal necroptosis

Authors: Chong Xu, Yilan Mei, Ruihan Yang, Qiudan Luo, Jienian Zhang, Xiaolin Kou, Jianfeng Hu, Yujie Wang, Yue Li, Rong Chen, Zhengping Zhang, Yuyuan Yao, Jian Sima

Journal: Cell Biosci

PubMed ID: 38678262

Doi: 10.1186/s13578-024-01230-8

Products & Services: Catalog Peptides

Intratumoural delivery of TRAIL mRNA induces colon cancer cell apoptosis

Authors: Tingxuan Gu, Mengqiao Wang, Xiaorong Fu, Xueli Tian, Juanjuan Bi, Ning Lu, Chen Chen, Shijia Yan, Ang Li, Luyun Wang, Xiang Li, Kangdong Liu, Zigang Dong

Journal: Biomed Pharmacother

PubMed ID: 38636395

Doi: 10.1016/j.biopha.2024.116603

Products & Services: Recombinant Proteins

A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development

Authors: Zhijuan Hu 1, Liang Yang 2, Maolei Zhang 2, Haite Tang 2, Yile Huang 3, Yujie Su 4, Yingzhe Ding 3, Chong Li 2, Mengfei Wang 4, Yunhao Zhou 4, Qing Zhang 5, Liman Guo 5, Yue Wu 5, Qianqian Wang 6, Ning Liu 6, Haoran Kang 2, Yi Wu 2, Deyang Yao 2, Yukun Li 4, Zifeng Ruan 4, Hao Wang 2, Feixiang Bao 2, Guopan Liu 3, Junwei Wang 2, Yaofeng Wang 3, Wuming Wang 7, Gang Lu 7, Dajiang Qin 8, Duanqing Pei 9, Wai-Yee Chan 7, Xingguo Liu

Journal: Cell Metab

PubMed ID: 38703762

Doi: 10.1016/j.cmet.2024.04.012

Products & Services: Monoclonal Antibody Services

Cryo-EM structure of the human Asc-1 transporter complex

Authors: Yaning Li , Yingying Guo, Angelika Bröer, Lu Dai, Stefan Brӧer , Renhong Yan

Journal: Nat Commun

PubMed ID: 38589439

Doi: 10.1038/s41467-024-47468-1

Products & Services: Protein and Antibody Isolation