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Structure-guided discovery of anti-CRISPR and anti-phage defense proteins

Authors: Ning Duan , Emily Hand , Mannuku Pheko , Shikha Sharma , Akintunde Emiola

Journal: Nat Commun

PubMed ID: 38245560

Doi: 10.1038/s41467-024-45068-7

Products & Services: Codon Optimization

Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques

Authors: Rajeshwer S Sankhala , Kerri G Lal , Jaime L Jensen , Vincent Dussupt , Letzibeth Mendez-Rivera , Hongjun Bai , Lindsay Wieczorek , Sandra V Mayer , Michelle Zemil , Danielle A Wagner , Samantha M Townsley , Agnes Hajduczki , William C Chang , Wei-Hung Chen , Gina C Donofrio , Ningbo Jian , Hannah A D King , Cynthia G Lorang , Elizabeth J Martinez , Phyllis A Rees , Caroline E Peterson , Fabian Schmidt , Tricia J Hart , Debra K Duso , Lawrence W Kummer , Sean P Casey , Jazmean K Williams , Shruthi Kannan , Bonnie M Slike , Lauren Smith , Isabella Swafford , Paul V Thomas , Ursula Tran , Jeffrey R Currier , Diane L Bolton , Edgar Davidson , Benjamin J Doranz , Theodora Hatziioannou , Paul D Bieniasz , Dominic Paquin-Proulx , William W Reiley , Morgane Rolland , Nancy J Sullivan , Sandhya Vasan , Natalie D Collins , Kayvon Modjarrad , Gregory D Gromowski , Victoria R Polonis , Nelson L Michael , Shelly J Krebs , M Gordon Joyce

Journal: Nat Commun

PubMed ID: 38172512

Doi: 10.1038/s41467-023-44265-0.

Products & Services: Antibody Modification and Purification Services

Therapeutic vaccination with lentiviral vector in HBV-persistent mice and two inactive HBsAg carriers

Authors: Yumeng Zhang, Maryline Bourgine , Yanmin Wan, Jieyu Song, Zongying Li, Yiqi Yu, Wangfang Jiang, Mingzhe Zhou, Cuiyuan Guo, Didier Santucci, Xiao Liang, Christian Brechot, Wenhong Zhang, Pierre Charneau, Hong Wu, Chao Qiu

Journal: Hepatology

PubMed ID: 37827470

Doi: 10.1016/j.jhep.2023.09.019

Products & Services: Peptide Synthesis

Increasing β-hexosaminidase A activity using genetically modified mesenchymal stem cells

Authors: Alisa A Shaimardanova , Daria S Chulpanova , Valeriya V Solovyeva 1, Shaza S Issa , Aysilu I Mullagulova , Angelina A Titova , Yana O Mukhamedshina , Anna V Timofeeva , Alexander M Aimaletdinov , Islam R Nigmetzyanov , Albert A Rizvanov

Journal: Neural Regen Res .

PubMed ID: 37488869

Doi: 10.4103/1673-5374.375328

Products & Services: Gene Synthesis

Minimalist Nanovaccine with Optimized Amphiphilic Copolymers for Cancer Immunotherapy

Authors: Le Niu , Yu Miao , Zhiqin Cao , Ting Wei , Jiafei Zhu , Maoyi Li , Boxiong Bai , Linfu Chen , Nanhui Liu , Feng Pan , Junjie Zhu , Cheng Wang , Yang Yang , Qian Chen

Journal: ACS Nano .

PubMed ID: 38230639

Doi: 10.1021/acsnano.3c10174

Products & Services: Peptide Synthesis

Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide

Authors: Tian Xie , Feitong Dong , Gongshe Han , Xinyue Wu , Peng Liu , Zike Zhang , Jianlong Zhong , Somashekarappa Niranjanakumari , Kenneth Gable , Sita D Gupta , Wenchen Liu , Peter J Harrison , Dominic J Campopiano , Teresa M Dunn , Xin Gong

Journal: Cell Rep .

PubMed ID: 38285738

Doi: 10.1016/j.celrep.2024.113717

Products & Services: Protein and Antibody Isolation

Stabilization of the Metastable Pre-Fusion Conformation of the SARS-CoV-2 Spike Glycoprotein through N-Linked Glycosylation of the S2 Subunit

Authors: Fuwen Zan, Yao Zhou, Ting Chen , Yahan Chen, Zhixia Mu, Zhaohui Qian , Xiuyuan Ou

Journal: Viruses.

PubMed ID: 38399999

Doi: 10.3390/v16020223

Products & Services: Gene Synthesis

Supramolecular Hydrogel with Ultra-Rapid Cell-Mediated Network Adaptation for Enhancing Cellular Metabolic Energetics and Tissue Regeneration

Authors: Zhuo Li, Boguang Yang, Zhengmeng Yang, Xian Xie, Zhengnan Guo, Jianyang Zhao, Ruinan Wang, Hao Fu, Pengchao Zhao, Xin Zhao, Guosong Chen, Gang Li, Fuxin Wei, Liming Bian

Journal: Adv Mater .

PubMed ID: 38295393

Doi: 10.1002/adma.202307176

Products & Services: Peptide Synthesis

Increasing the Pentose Phosphate Pathway Flux to Improve Plasmid DNA Production in Engineered

Authors: Mitzi de la Cruz, Flavio Kunert, Hilal Taymaz-Nikerel, Juan-Carlos Sigala, Guillermo Gosset, Jochen Büchs, Alvaro R Lara

Journal: Microorganisms

PubMed ID: 38257977

Doi: 10.3390/microorganisms12010150

Products & Services: Molecular Biology Reagents

Self-cascade deoxynivalenol detoxification by an artificial enzyme with bifunctions of dehydrogenase and aldo/keto reductase from genome mining

Authors: Jiafeng Niu, Ruxue Yan, Huimin Zhou, Bin Ma, Zhaoxin Lu, Fanqiang Meng, Fengxia Lu, Ping Zhu

Journal: Int J Biol Macromol

PubMed ID: 38246466

Doi: 10.1016/j.ijbiomac.2024.129512

Products & Services: Recombinant Proteins