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The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma

Authors: Stephan Spahn, Fabian Kleinhenz, Ekaterina Shevchenko, Aaron Stahl, Yvonne Rasen, Christine Geisler, Kristina Ruhm, Marion Klaumuenzer, Thales Kronenberger, Stefan A Laufer, Holly Sundberg-Malek, Khac Cuong Bui, Marius Horger, Saskia Biskup, Klaus Schulze-Osthoff, Markus Templin, Nisar P Malek, Antti Poso, Michael Bitzer

Journal: Nat Commun

PubMed ID: 38346946

Doi: 10.1038/s41467-024-45247-6

Products & Services: Molecular Biology Reagents

Autoinhibition and activation of myosin VI revealed by its cryo-EM structure

Authors: Fengfeng Niu, Lingxuan Li, Lei Wang, Jinman Xiao, Shun Xu, Yong Liu, Leishu Lin, Cong Yu, Zhiyi Wei

Journal: Nat Commun

PubMed ID: 38331992

Doi: 10.1038/s41467-024-45424-7

Products & Services: Protein and Antibody Isolation

Cutting Edge: Characterization of Low Copy Number Human Angiotensin-Converting Enzyme 2-Transgenic Mice as an Improved Model of SARS-CoV-2 Infection

Authors: Christine M Bradshaw, Teodora Georgieva, Trevor N Tankersley, Tama Taylor-Doyle, Larry Johnson, Jennifer L Uhrlaub, David Besselsen, Janko Ž Nikolich

Journal: J Immunol

PubMed ID: 38197714

Doi: 10.4049/jimmunol.2300591

Products & Services: Protein and Antibody Isolation

Enhancing CAR Macrophage Efferocytosis Via Surface Engineered Lipid Nanoparticles Targeting LXR Signaling

Authors: Skylar T Chuang, Joshua B Stein, Sarah Nevins, Cemile Kilic Bektas, Hye Kyu Choi, Wan-Kyu Ko, Hyunjun Jang, Jihun Ha, Ki-Bum Lee

Journal: Adv Mater

PubMed ID: 38353580

Doi: 10.1002/adma.202308377

Products & Services: Protein and Antibody Isolation

Molecular Characterization of Plant Volatile Compound Interactions with Odorant-Binding Proteins

Authors: Qi Qian, Xin Guo, Lingjie Wu, Jiarong Cui, Huiying Gao, Yajun Yang, Hongxing Xu, Zhongxian Lu, Pingyang Zhu

Journal: Plants (Basel)

PubMed ID: 38498446

Doi: 10.3390/plants13040479

Products & Services: Protein and Antibody Isolation

Mitochondrial amidoxime-reducing component 1 p.Ala165Thr increases protein degradation mediated by the proteasome

Authors: Tanmoy Dutta, Kavitha Sasidharan, Ester Ciociola, Grazia Pennisi, Francesca R Noto, Lohitesh Kovooru, Tobias Kroon, Anna Lindblom, Yue Du, Mohammad Pirmoradian, Simonetta Wallin, Rosellina M Mancina, Daniel Lindén, Stefano Romeo

Journal: Liver Int

PubMed ID: 38375985

Doi: 10.1111/liv.15857

Products & Services: Mutagenesis Services

Borrelia miyamotoi BipA-like protein, BipM, is a candidate serodiagnostic antigen distinguishing between Lyme disease and relapsing fever Borrelia infections

Authors: Kevin S Brandt, Brittany A Armstrong, Irina Goodrich, Robert D Gilmore

Journal: Ticks Tick Borne Dis

PubMed ID: 38367587

Doi: 10.1016/j.ttbdis.2024.102324

Products & Services: Recombinant Proteins

Fusarium graminearum rapid alkalinization factor peptide negatively regulates plant immunity and cell growth via the FERONIA receptor kinase

Authors: Yujie Wang, Xin Liu, Bingqin Yuan, Xue Chen, Hanxi Zhao, Qurban Ali, Minghong Zheng, Zheng Tan, Hemin Yao, Shuqing Zheng, Jingni Wu, Jianhong Xu, Jianrong Shi, Huijun Wu, Xuewen Gao, Qin Gu

Journal: Plant Biotechnol J

PubMed ID: 38344883

Doi: 10.1111/pbi.14303

Products & Services: Gene Synthesis

Identification of closely related species in through Analysis of Whole-Genome

Authors: Guihong Qi, Lijun Hao, Yutong Gan, Tianyi Xin, Qian Lou, Wenjie Xu, Jingyuan Song

Journal: Front Microbiol

PubMed ID: 38450170

Doi: 10.3389/fmicb.2024.1323572

Products & Services: Synthetic Guide RNA

Chimeric nanobody-decorated liposomes by self-assembly

Authors: Md Mofizur Rahman, Jing Wang, Guosheng Wang, Zhipeng Su, Yizeng Li, Yundi Chen, Jinguo Meng, Yao Yao, Lefei Wang, Stephan Wilkens, Jifu Tan, Juntao Luo, Tao Zhang, Chuandong Zhu, Sung Hyun Cho, Lixue Wang, Luke P Lee, Yuan Wan

Journal: Nat Nanotechnol

PubMed ID: 38374413

Doi: 10.1038/s41565-024-01620-6

Products & Services: Recombinant Proteins