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A network pharmacological approach for the identification of potential therapeutic targets of - a complex traditional Siddha formulation

Authors: Agnes Preethy H, Yanamandram Balasubramanian Venkatakrishnan, Vigneshwar Ramakrishnan, Uma Maheswari Krishnan

Journal: J Biomol Struct Dyn

PubMed ID: 38459935

Doi: 10.1080/07391102.2024.2322612

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The eukaryotic-like characteristics of small GTPase, roadblock and TRAPPC3 proteins from Asgard archaea

Authors: Linh T Tran, Caner Akıl, Yosuke Senju, Robert C Robinson

Journal: Commun Biol

PubMed ID: 38472392

Doi: 10.1038/s42003-024-05888-1

Products & Services: DNA Sequencing

Design and synthesis of APN and 3CLpro dual-target inhibitors based on STSBPT with anticoronavirus activity

Authors: Youle Zheng, Jin Feng, Yanbin Song, Yixin Yu, Min Ling, Mengjia Zhang, Haijiao Xie, Wentao Li

Journal: J Med Virol

PubMed ID: 38483056

Doi: 10.1002/jmv.29512

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Characterization of c-di-AMP signaling in the periodontal pathobiont, Treponema denticola

Authors: Aidan D Moylan, Dhara T Patel, Claire O'Brien, Edward J A Schuler, Annie N Hinson, Richard T Marconi, Daniel P Miller

Journal: Mol Oral Microbiol

PubMed ID: 38436552

Doi: 10.1111/omi.12458

Products & Services: Protein and Antibody Isolation

Machine learning developed a CD8 exhausted T cells signature for predicting prognosis, immune infiltration and drug sensitivity in ovarian cancer

Authors: Rujun Chen, Yicai Zheng, Chen Fei, Jun Ye, He Fei

Journal: Sci Rep

PubMed ID: 38461331

Doi: 10.1038/s41598-024-55919-4

Products & Services: Molecular Biology Reagents

Safety and immunogenicity of CoronaVac and ChAdOx1 heterologous prime-boost vaccines in an overweight population in Chiang Mai, Thailand

Authors: Kriangkrai Chawansuntati, Supachai Sakkhachornphop, Sayamon Hongjaisee, Saranta Freeouf, Patumrat Sripan, Nattaya Nusartsang, Romanee Chaiwarith, Tavitiya Sudjaritruk, Khuanchai Supparatpinyo, Jiraprapa Wipasa

Journal: Vaccine X

PubMed ID: 38549951

Doi: 10.1016/j.jvacx.2024.100475

Products & Services: Molecular Biology Reagents

Mosquito E-20-Monooxygenase Gene Knockout Increases Dengue Virus Replication in Cells

Authors: Bo Li, Di Wang, Xiaoxue Xie, Xiaoli Chen, Guorui Liang, Dan Xing, Teng Zhao, Jiahong Wu, Xinyu Zhou, Chunxiao Li

Journal: Viruses

PubMed ID: 38675868

Doi: 10.3390/v16040525

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Porcine HERC6 acts as major E3 ligase for ISGylation and is auto-ISGylated for effective ISGylation in porcine

Authors: Cuiyu Ba, Chaonan Tian, Xueying Bo, Chang Xu, Yi Zhang, Xiangyu Sun, Yuchen Nan, Chunyan Wu

Journal: Microb Pathog

PubMed ID: 38554778

Doi: 10.1016/j.micpath.2024.106633

Products & Services: Protein and Antibody Isolation

FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells

Authors: Ke Cong, Nathan MacGilvary, Silviana Lee, Shannon G MacLeod, Jennifer Calvo, Min Peng, Arne Nedergaard Kousholt, Tovah A Day, Sharon B Cantor

Journal: Nat Commun

PubMed ID: 38521768

Doi: 10.1038/s41467-024-46824-5

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Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons

Authors: Nan Luo, Qiang Huang, Liting Dong, Wenqing Liu, Jinghui Song, Hanxiao Sun, Hao Wu, Yuan Gao, Chengqi Yi

Journal: Nat Biotechnol

PubMed ID: 38448662

Doi: 10.1038/s41587-024-02165-8

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