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Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors
Authors: Kiara N Berríos, Aleksia Barka, Jasleen Gill, Juan C Serrano, Peter F Bailer, Jared B Parker, Niklaus H Evitt, Kiran S Gajula, Junwei Shi, Rahul M Kohli
Journal: Nucleic Acids Res
PubMed ID: 38261989
Doi: 10.1093/nar/gkae024
Products & Services: Molecular Biology Reagents   
Poly-γ-glutamylation of biomolecules
Authors: Ghader Bashiri, Esther M M Bulloch, William R Bramley, Madison Davidson, Stephanie M Stuteley, Paul G Young, Paul W R Harris, Muhammad S H Naqvi, Martin J Middleditch, Michael Schmitz, Wei-Chen Chang, Edward N Baker, Christopher J Squire
Journal: Nat Commun
PubMed ID: 38346985
Doi: 10.1038/s41467-024-45632-1
Products & Services: Gene Synthesis   
Cross-Phosphorylation between AgrC Histidine Kinase and the Noncognate Response Regulator Lmo1172 in under Benzalkonium Chloride Stress
Authors: Tao Yu, Xiaojie Jiang, Xiaobo Xu, Ping Xu, Shuxing Qiu, Junlei Yin, David P Hamilton, Xiaobing Jiang
Journal: Microorganisms
PubMed ID: 38399796
Doi: 10.3390/microorganisms12020392
Products & Services: DNA Sequencing   
A quaternary ammonium-based nanosystem enables delivery of CRISPR/Cas9 for cancer therapy
Authors: Mengzhu Zhang, Siyu Sun, Xiao Liang, Zengguang Liu, Jiaxin Yin, Quanshun Li, Shengcai Yang
Journal: Biomater Sci
PubMed ID: 38240497
Doi: 10.1039/d3bm01629c
Products & Services: Synthetic sgRNA and crRNA Service   
Enhancing sensitivity of qPCR assays targeting Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae by using a mutant Taq DNA polymerase
Authors: Selin Nar Otgun, Canan Zohre Ketre Kolukirik, Nuriye Unal Sahin, Mustafa Kolukirik, Gozde Girgin Ozgumus, Meral Turan, Mert Elmas, Selcuk Kilic
Journal: J Microbiol Methods
PubMed ID: 38360298
Doi: 10.1016/j.mimet.2024.106899
Products & Services: Gene Synthesis   
Nanobody-Mediated Dualsteric Engagement of the Angiotensin Receptor Broadens Biased Ligand Pharmacology
Authors: Nayara Braga Emidio , Brandi M Small , Amanda R Keller , Ross W Cheloha , Laura M Wingler
Journal: Mol Pharmacol
PubMed ID: 38164609
Doi: 10.1124/molpharm.123.000797
Products & Services: Peptide Synthesis   
DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α
Authors: Aidi Gao, Mingxia Zhang, Shuang Qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao
Journal: Cell Death Dis
PubMed ID: 38402183
Doi: 10.1038/s41419-024-06552-6
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment
Authors: Yin Li, Manling Jiang, Ling Aye, Li Luo, Yong Zhang, Fengkai Xu, Yongqi Wei, Dan Peng, Xiang He, Jie Gu, Xiaofang Yu, Guoping Li, Di Ge, Chunlai Lu
Journal: Nat Commun .
PubMed ID: 38331898
Doi: 10.1038/s41467-024-45340-w
Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery
Authors: Liang Leng, Zhichao Xu, Bixia Hong, Binbin Zhao, Ya Tian, Can Wang, Lulu Yang, Zhongmei Zou, Lingyu Li, Ke Liu, Wanjun Peng, Jiangning Liu, Zhoujie An, Yalin Wang, Baozhong Duan, Zhigang Hu, Chuan Zheng, Sanyin Zhang, Xiaodong Li, Maochen Li, Zhaoyu Liu, Zenghao Bi, Tianxing He, Baimei Liu, Huahao Fan, Chi Song, Yigang Tong, Shilin Chen
Journal: Nat Commun .
PubMed ID: 38378731
Doi: 10.1038/s41467-024-45690-5
Products & Services: Catalog Antibody   
Carotenoid cleavage enzymes evolved convergently to generate the visual chromophore
Authors: Yasmeen J Solano , Michael P Everett , Kelly S Dang , Jude Abueg , Philip D Kiser
Journal: Nature Chemical Biology
PubMed ID: 38355721
Doi: 10.1038/s41589-024-01554-z
Products & Services: Plasmid DNA Preparation   

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