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Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria

Authors: Stian Foss , Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz , Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg

Journal: Nature Communications

PubMed ID: 38453922

Doi: 10.1038/s41467-024-46321-9

Products & Services: Gene Synthesis

An alphacoronavirus polymerase structure reveals conserved replication factor functions

Authors: Thomas K Anderson, Peter J Hoferle, Kennan J Chojnacki, Kenneth W Lee, Joshua J Coon, Robert N Kirchdoerfer

Journal: Nucleic Acids Research

PubMed ID: 38442273

Doi: 10.1093/nar/gkae153

Products & Services: Codon Optimization

Determinants of CRISPR Cas12a nuclease activation by DNA and RNA targets

Authors: Eric A Nalefski, Remy M Kooistra, Ishira Parikh, Samantha Hedley, Karunya Rajaraman, Damian Madan

Journal: Nucleic Acids Research

PubMed ID: 38477377

Doi: 10.1093/nar/gkae152

Products & Services: Gene Synthesis

Fibrinogen deposition promotes neuroinflammation and fibrin-derived γ peptide ameliorates neurological deficits after ischemic stroke

Authors: Lu Han, Yaying Song, Weiwei Xiang, Ze Wang, Yishu Wang, Xiajun Zhou, De-Sheng Zhu, Yangtai Guan

Journal: Int Immunopharmacol

PubMed ID: 38489969

Doi: 10.1016/j.intimp.2024.111831

Products & Services: Catalog Peptides

A Novel Polymer Nanoparticle Polydimethyl Diallyl Ammonium Chloride as An Adjuvant Enhances the Immune Response of SARS-CoV-2 Subunit Vaccine

Authors: Lili Ren, Chengcheng Ouyang, Shuqing Zhao, Qiqi Zheng, Weilu Guo, Baochao Fan, Jinzhu Zhou, Wei Zhang, Mi Hu, Jizong Li, Bin Li

Journal: Adv Healthc Mater

PubMed ID: 38436662

Doi: 10.1002/adhm.202304575

Products & Services: Protein and Antibody Isolation

Hepcidin contributes to largemouth bass (Micropterus salmoides) against bacterial infections

Authors: Weixiang Zhang, Bo Li, Ruying Yu, Wenyan Xu, Xiaoling Liu, Jianguo Su, Gailing Yuan

Journal: Int J Biol Macromol

PubMed ID: 38556234

Doi: 10.1016/j.ijbiomac.2024.131144

Products & Services: Peptide Synthesis

Expression, purification, and biological activity evaluation of cathepsin L in mammalian cells

Authors: Wenwen Zhou, Baoqing You, Yifan Zheng, Shuyi Si, Yan Li, Jing Zhang

Journal: Biosci Biotechnol Biochem

PubMed ID: 38271604

Doi: 10.1093/bbb/zbae005

Products & Services: Molecular Biology Reagents

Activation of Piezo1 increases the sensitivity of breast cancer to hyperthermia therapy

Authors: Shao-Kang Wang, Xiao-Ting Zhang, Xuan-Yao Jiang, Bi-Jiang Geng, Tao-Lin Qing, Lei Li, Yun Chen, Jin-Feng Li, Xiao-Fang Zhang, Shuo-Gui Xu, Jiang-Bo Zhu, Yu-Ping Zhu, Mei-Tang Wang, Ji-Kuai Chen

Journal: Open Med (Wars)

PubMed ID: 38463518

Doi: 10.1515/med-2024-0898

Products & Services: Protein and Antibody Isolation

Integrative analysis of metabolism subtypes and identification of prognostic metabolism-related genes for glioblastoma

Authors: Jiahui Li, Yutian Wei, Jiali Liu, Shupeng Cheng, Xia Zhang, Huaide Qiu, Jianan Li, Chuan He

Journal: Biosci Rep

PubMed ID: 38419527

Doi: 10.1042/BSR20231400

Products & Services: PCR Cloning and Subcloning

Development and Evaluation of an Immunoinformatics-Based Multi-Peptide Vaccine against Infection

Authors: Sean Jeffreys, Megan P Tompkins, Jadelynn Aki, Sara B Papp, James P Chambers, M Neal Guentzel, Chiung-Yu Hung, Jieh-Juen Yu, Bernard P Arulanandam

Journal: Vaccines (Basel)

PubMed ID: 38675740

Doi: 10.3390/vaccines12040358

Products & Services: Molecular Biology Reagents