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GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection

Authors: Jizhong Wang, Jitao Liu, Fan Yang, Yinghao Sun, Jiaohua Chen, Jie Liu, Tucheng Sun, Ruixin Fan, Fang Pei, Songyuan Luo, Jie Li, Jianfang Luo

Journal: Nature Communications

PubMed ID: 39966416

Doi: 10.1038/s41467-025-57011-5

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

Authors: Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T Yustein, Michelle A Kelliher, Lihua Julie Zhu, Sara K Deibler, Sunil K Malonia, Michael R Green

Journal: Nature Communications

PubMed ID: 39894896

Doi: 10.1038/s41467-025-56632-0

Products & Services: Plasmid DNA Preparation

Synthetic lethality of mRNA quality control complexes in cancer

Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik

Journal: Nature

PubMed ID: 39910291

Doi: 10.1038/s41586-024-08398-6

Products & Services: Custom Vector Construction

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy

Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang

Journal: Adv Mater

PubMed ID: 39955648

Doi: 10.1002/adma.202416574

Products & Services: Recombinant Proteins

Elastin-like polypeptide: A novel titanification biomacromolecule for green and ultrafast synthesis of biotitania nanoparticles via biomimetic mineralization

Authors: Lixi Cai, Jinlin Zheng, Lixing Liu, Guangya Zhang, Yuanqing Lin

Journal: Int J Biol Macromol

PubMed ID: 40015400

Doi: 10.1016/j.ijbiomac.2025.141449

Products & Services: Gene Synthesis

A Granzyme B‑Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes

Authors: Yanfang Wang, Yanping Sun, Xiuwen Zhang, Shenqiang Wang, Xuehui Huang, Kairui Xu, Yun Liu, Yingqi Huang, Jianchang Xu, Xinwei Wei, Hao Cheng, Liqiang Pan, Jinqiang Wang, Zhen Gu

Journal: Journal of the American Chemical Society

PubMed ID: 39869523

Doi: 10.1021/jacs.4c13644

Products & Services: Gene Synthesis

Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival

Authors: Wen Wei, Xueqin Gao, Jiawei Qian, Lei Li, Chen Zhao, Li Xu, Yanfei Zhu, Zhenzhen Liu, Nengrong Liu, Xueqing Wang, Zhicong Jin, Bowen Liu, Lan Xu, Jin Dong, Suping Zhang, Jiarong Wang, Yumu Zhang, Yao Yu, Zhanjun Yan, Yanjun Yang, Jie Lu, Yixuan Fang, Na Yuan, Jianrong Wang

Journal: Journal of Clinical Investigation

PubMed ID: 39589832

Doi: 10.1172/JCI177375.

Products & Services: Protein and Antibody Isolation

The structure of FCGBP is formed as a disulfide‐mediated homodimer between its C‐terminal domains

Authors: Erik Ehrencrona, Pablo Gallego, Sergio Trillo-Muyo, Maria-Jose Garcia-Bonete, Christian V Recktenwald, Gunnar C Hansson, Malin E V Johansson

Journal: FEBS Journal

PubMed ID: 39754272

Doi: 10.1111/febs.17383

Products & Services: Gene Synthesis

Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism

Authors: Bartlomiej Taciak, Maciej Bialasek, Malgorzata Kubiak, Ilona Marszalek, Malgorzata Gorczak, Olha Osadchuk, Daria Kurpiel, Damian Strzemecki, Karolina Barwik, Marcin Skorzynski, Julia Nowakowska, Waldemar Lipiński, Łukasz Kiraga, Jan Brancewicz, Robert Klopfleisch, Łukasz Krzemiński, Emilia Gorka, Anna Smolarska, Irena Padzinska-Pruszynska, Małgorzata Siemińska, Jakub Guzek, Jan Kutner, Marlena Kisiala, Krzysztof Wozniak, Giacomo Parisi, Roberta Piacentini, Luca Cassetta, Lesley M Forrester, Lubomir Bodnar, Tobias Weiss, Alberto Boffi, Paulina Kucharzewska, Tomasz P Rygiel, Magdalena Krol

Journal: Nature Communications

PubMed ID: 39900573

Doi: 10.1038/s41467-025-56637-9

Products & Services: Bacterial Expression