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A mechanism that ensures non-selective cytoplasm degradation by autophagy

Authors: Tetsuya Kotani, Yuji Sakai, Hiromi Kirisako, Chika Kakuta, Soichiro Kakuta, Yoshinori Ohsumi, Hitoshi Nakatogawa

Journal: Nat Commun

PubMed ID: 37726301

Doi: 10.1038/s41467-023-41525-x

Products & Services: Gene Synthesis

A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses

Authors: Sneha Vishwanath, George William Carnell, Matteo Ferrari, Benedikt Asbach, Martina Billmeier, Charlotte George, Maria Suau Sans, Angalee Nadesalingam, Chloe Qingzhou Huang, Minna Paloniemi, Hazel Stewart, Andrew Chan, David Arthur Wells, Patrick Neckermann, David Peterhoff, Sebastian Einhauser, Diego Cantoni, Martin Mayora Neto, Ingo Jordan, Volker Sandig, Paul Tonks, Nigel Temperton, Simon Frost, Katharina Sohr, Maria Teresa Lluesma Ballesteros, Farzad Arbabi, Johannes Geiger, Christian Dohmen, Christian Plank, Rebecca Kinsley, Ralf Wagner, Jonathan Luke Heeney

Journal: Nat Biomed Eng

PubMed ID: 37749309

Doi: 10.1038/s41551-023-01094-2

Products & Services: Protein and Antibody Isolation

Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics

Authors: Yifan Wang, Weiye Deng, DaeYong Lee, Long Yan, Yifei Lu, Shiyan Dong, Kristin Huntoon, Abin Antony, Xuefeng Li, Rui Ye, Yan Zhao, Feiyan Zhao, Benjamin R Schrank, JongHoon Ha, Minjeong Kang, Mingming Yang, Ping Gong, Philip L Lorenzi, Lin Tan, Thomas D Gallup, Sarah K Tang, Zhaogang Yang, Jing Li, Nina N Sanford, Hongmei Wang, Betty Y S Kim, Wen Jiang

Journal: Nat Nanotechnol

PubMed ID: 37723279

Doi: 10.1038/s41565-023-01502-3

Products & Services: Recombinant Proteins

Controlled and customizable baculovirus NOS3 gene delivery using PVA-based hydrogel systems

Authors: Sabrina Schaly, Paromita Islam, Jacqueline L Boyajian, Rahul Thareja, Ahmed Abosalha, Karan Arora, Dominique Shum-Tim, Satya Prakash

Journal: PLoS ONE

PubMed ID: 37733661

Doi: 10.1371/journal.pone.0290902

Products & Services: Recombinant Proteins

Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase

Authors: Beatriz Piniello, Javier Macías-León, Shun Miyazaki, Ana García-García, Ismael Compañón, Mattia Ghirardello, Víctor Taleb, Billy Veloz, Francisco Corzana, Atsushi Miyagawa, Carme Rovira, Ramon Hurtado-Guerrero

Journal: Nat Commun

PubMed ID: 37723184

Doi: 10.1038/s41467-023-41238-1

Products & Services: Gene Synthesis

Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication

Authors: Carol Cho, Christian Ganser, Takayuki Uchihashi, Koichi Kato, Ji-Joon Song

Journal: Commun Biol

PubMed ID: 37770645

Doi: 10.1038/s42003-023-05373-1

Products & Services: Insect Expression

Downregulation of AP1S1 causes the lysosomal degradation of EGFR in non-small cell lung cancer

Authors: Jangho Jeong, Ye Eun Hwang, Minwoo Lee, Seula Keum, Seongeun Song, Jung-Woong Kim, Jee-Hye Choi, Sangmyung Rhee

Journal: J Cell Physiol

PubMed ID: 37659097

Doi: 10.1002/jcp.31112

Products & Services: Custom DNA/RNA Oligos

Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

Authors: Mark M Painter, Timothy S Johnston, Kendall A Lundgreen, Jefferson J S Santos, Juliana S Qin, Rishi R Goel, Sokratis A Apostolidis, Divij Mathew, Bria Fulmer, Justine C Williams, Michelle L McKeague, Ajinkya Pattekar, Ahmad Goode, Sean Nasta, Amy E Baxter, Josephine R Giles, Ashwin N Skelly, Laura E Felley, Maura McLaughlin, Joellen Weaver, Oliva Kuthuru, Jeanette Dougherty, Sharon Adamski, Sherea Long, Macy Kee, Cynthia Clendenin, Ricardo da Silva Antunes, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Alexander C Huang, Daniel J Rader, Scott E Hensley, Paul Bates, Allison R Greenplate, E John Wherry

Journal: Nat Immunol

PubMed ID: 37735592

Doi: 10.1038/s41590-023-01613-y

Products & Services: Peptide Synthesis

Freshwater connectivity transforms spatially integrated signals of biodiversity

Authors: Joanne E Littlefair, José S Hleap, Vince Palace, Michael D Rennie, Michael J Paterson, Melania E Cristescu

Journal: Proc Biol Sci

PubMed ID: 37700653

Doi: 10.1098/rspb.2023.0841

Products & Services: Molecular Biology Reagents

Detection of High-Risk Paraneoplastic Antibodies against TRIM9 and TRIM67 Proteins

Authors: Christopher M Bartley, Thomas T Ngo, Le Duy Do, Anastasia Zekeridou, Ravi Dandekar, Sergio Muñiz-Castrillo, Bonny D Alvarenga, Kelsey C Zorn, Asritha Tubati, Anne-Laurie Pinto, Weston D Browne, Patrick W Hullett, Mark Terrelonge, Ryan D Schubert, Amanda L Piquet, Binxia Yang, Mayra Montalvo, Andrew F Kung, Sabrina A Mann, Maulik P Shah, Michael D Geschwind, Jeffrey M Gelfand, Joseph L DeRisi, Sean J Pittock, Jérôme Honnorat, Samuel J Pleasure, Michael R Wilson

Journal: Ann Neurol

PubMed ID: 37632288

Doi: 10.1002/ana.26776

Products & Services: Recombinant Proteins