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PTBP2 attenuation facilitates fibroblast to neuron conversion by promoting alternative splicing of neuronal genes

Authors: Binglin Zhu, Emily Fisher, Li Li, Ping Zhong, Zhen Yan, Jian Feng

Journal: Stem Cell Reports

PubMed ID: 37832540

Doi: 10.1016/j.stemcr.2023.09.012

Products & Services: Molecular Biology Reagents

Hem25p is required for mitochondrial IPP transport in fungi

Authors: Jonathan Tai, Rachel M Guerra, Sean W Rogers, Zixiang Fang, Laura K Muehlbauer, Evgenia Shishkova, Katherine A Overmyer, Joshua J Coon, David J Pagliarini

Journal: Nat Cell Biol

PubMed ID: 37813972

Doi: 10.1038/s41556-023-01250-5

Products & Services: Codon Optimization

A non-canonical role of endothelin converting enzyme 1 (ECE1) in promoting lung cancer development via directly targeting protein kinase B (AKT)

Authors: Li Chen, Yikai Lu, Mengmeng Zhao, Junfang Xu, Yan Wang, Qinghua Xu, Yajuan Cao, Haipeng Liu

Journal: J Gene Med

PubMed ID: 37897251

Doi: 10.1002/jgm.3612

Products & Services: Protein and Antibody Isolation

Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute

Authors: Xiaopan Gao, Kun Shang, Kaixiang Zhu, Linyue Wang, Zhixia Mu, Xingke Fu, Xia Yu, Bo Qin, Hongtao Zhu, Wei Ding, Sheng Cui

Journal: Nature

Doi: doi.org/10.1038/s41586-023-06665-6

Products & Services: Gene Synthesis

A critical role for iron and zinc homeostatic systems in the evolutionary adaptation of to metal restriction

Authors: Joy R Paterson, Joshua M Wadsworth, Ping Hu, Gary J Sharples

Journal: Microb Genom

PubMed ID: 38054971

Doi: 10.1099/mgen.0.001153

Products & Services: Protein and Antibody Isolation

A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels

Authors: Jian Zhou, Claudia Cattoglio, Yingyao Shao, Harini P Tirumala, Carlo Vetralla, Sameer S Bajikar, Yan Li, Hu Chen, Qi Wang, Zhenyu Wu, Bing Tang, Mahla Zahabiyon, Aleksandar Bajic, Xiangling Meng, Jack J Ferrie, Anel LaGrone, Ping Zhang, Jean J Kim, Jianrong Tang, Zhandong Liu, Xavier Darzacq, Nathaniel Heintz, Robert Tjian, Huda Y Zoghbi

Journal: Genes Dev

PubMed ID: 37890975

Doi: 10.1101/gad.350733.123

Products & Services: Protein and Antibody Isolation

Overexpressing CsPSY1 Gene of Tea Plant, Encoding a Phytoene Synthase, Improves α-Carotene and β-Carotene Contents in Carrot

Authors: Jing-Wen Li, Ping Zhou, Yuan-Jie Deng, Zhi-Hang Hu, Xing-Hui Li, Xuan Chen, Ai-Sheng Xiong, Jing Zhuang

Journal: Mol Biotechnol

PubMed ID: 37897587

Doi: 10.1007/s12033-023-00942-5

Products & Services: Protein and Antibody Isolation

Rational Design of Taxadiene Hydroxylase by Ancestral Enzyme Construction and the Elucidation of Key Amino Acids

Authors: Zihan Zhang, Longhao Huang, Zhi-Jun Zhang, Jian-He Xu, Hui-Lei Yu

Journal: Biochemistry

PubMed ID: 37902563

Doi: 10.1021/acs.biochem.3c00411

Products & Services: Protein and Antibody Isolation

Single Amino Acid Mutation Decouples Photochemistry of the BLUF Domain from the Enzymatic Function of OaPAC and Drives the Enzyme to a Switched-on State

Authors: Jinnette Tolentino Collado, Emoke Bodis, Jonatan Pasitka, Mihaly Szucs, Zsuzsanna Fekete, Nikolett Kis-Bicskei, Elek Telek, Kinga Pozsonyi, Sofia M Kapetanaki, Greg Greetham, Peter J Tonge, Stephen R Meech, Andras Lukacs

Journal: J Mol Biol

PubMed ID: 37827329

Doi: 10.1016/j.jmb.2023.168312

Products & Services: Protein and Antibody Isolation

FHL1 promotes chikungunya and o'nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design

Authors: Wern Hann Ng, Xiang Liu, Zheng L Ling, Camilla N O Santos, Lucas S Magalhães, Andrew J Kueh, Marco J Herold, Adam Taylor, Joseph R Freitas, Sandra Koit, Sainan Wang, Andrew R Lloyd, Mauro M Teixeira, Andres Merits, Roque P Almeida, Nicholas J C King, Suresh Mahalingam

Journal: Nat Commun

PubMed ID: 37884534

Doi: 10.1038/s41467-023-42330-2

Products & Services: Protein and Antibody Isolation