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页码: 98/5233 每页显示数量

Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities

Authors: Linjiao Zhou, Uriel Ortega-Rodriguez, Matthew J Flores, Yasuyuki Matsumoto, John Q Bettinger, Wells W Wu, Yaqin Zhang, Su-Ryun Kim, Thomas G Biel, Jordan D Pritts, Rong-Fong Shen, V Ashutosh Rao, Tongzhong Ju.

Journal: Nature Communications

PubMed ID: 40000644

Doi: 10.1038/s41467-025-57143-8

Products & Services: Codon Optimization

Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies

Authors: Yan-Ruide Li, Ying Fang, Siyue Niu, Yichen Zhu, Yuning Chen, Zibai Lyu, Enbo Zhu, Yanxin Tian, Jie Huang, Valerie Rezek, Scott Kitchen, Tzung Hsiai, Jin J Zhou, Pin Wang, Wanxing Chai-Ho, Sunmin Park, Christopher S Seet, Caspian Oliai, Lili Yang

Journal: Nature Communications

PubMed ID: 39893165

Doi: 10.1038/s41467-025-56270-6

Products & Services: Gene Fragments

Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses

Authors: Young-Jun Park, Chen Liu, Jimin Lee, Jack T Brown, Cheng-Bao Ma, Peng Liu, Risako Gen, Qing Xiong, Samantha K Zepeda, Cameron Stewart, Amin Addetia, Caroline J Craig, M Alejandra Tortorici, Abeer N Alshukairi, Tyler N Starr, Huan Yan, David Veesler

Journal: Cell

PubMed ID: 39922192

Doi: 10.1016/j.cell.2024.12.032

Products & Services: Codon Optimization

Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells

Authors: Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M Szewczyk, Ka Yang, Yani Zhao, Michael A Stashko, Jacqueline L Norris-Drouin, Jarod M Waybright, Serap Beldar, Justin M Rectenwald, Angie L Mordant, Thomas S Webb, Laura E Herring, Cheryl H Arrowsmith, Suzanne Ackloo, Steven P Gygi, Robert K McGinty, Dalia Barsyte-Lovejoy, Pengda Liu, Levon Halabelian, Lindsey I James, Kenneth H Pearce, Stephen V Frye

Journal: Nature Communications

PubMed ID: 39994194

Doi: 10.1038/s41467-025-57005-3

Products & Services: Peptide Synthesis

Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350

Authors: M Gordon Joyce, Wei Bu, Wei-Hung Chen, Rebecca A Gillespie, Sarah F Andrews, Adam K Wheatley, Yaroslav Tsybovsky, Jaime L Jensen, Tyler Stephens, Madhu Prabhakaran, Brian E Fisher, Sandeep R Narpala, Meghna Bagchi, Adrian B McDermott, Gary J Nabel, Peter D Kwong, John R Mascola, Jeffrey I Cohen, Masaru Kanekiyo

Journal: Immunity

PubMed ID: 39909035

Doi: 10.1016/j.immuni.2025.01.010

Products & Services: Recombinant Antibody Expression

Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates

Authors: Prakash Jadhav, Xueying Liang, Ahmadullah Ansari, Bin Tan, Haozhou Tan, Kan Li, Xiang Chi, Alexandra Ford, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang

Journal: Nature Communications

PubMed ID: 39948104

Doi: 10.1038/s41467-025-56902-x

Products & Services: Codon Optimization

Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling

Authors: Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

Journal: Nature Communications

PubMed ID: 39920161

Doi: 10.1038/s41467-025-56713-0

Products & Services: Peptide Synthesis

Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

Authors: Congcong Chen, Yang Li, Yayun Gu, Qiqi Zhai, Songwei Guo, Jun Xiang, Yuan Xie, Mingxing An, Chenmeijie Li, Na Qin, Yanan Shi, Liu Yang, Jun Zhou, Xianfeng Xu, Ziye Xu, Kai Wang, Meng Zhu, Yue Jiang, Yuanlin He, Jing Xu, Rong Yin, Liang Chen, Lin Xu, Juncheng Dai, Guangfu Jin, Zhibin Hu, Cheng Wang, Hongxia Ma, Hongbing Shen

Journal: Nature Communications

PubMed ID: 39910069

Doi: 10.1038/s41467-025-56725-w

Products & Services: Gene Synthesis

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ

Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch

Journal: Nature Communications

PubMed ID: 39952913

Doi: 10.1038/s41467-025-56824-8

Products & Services: Protein Electrophoresis and Western

Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

Authors: Cheng-Bao Ma, Chen Liu, Young-Jun Park, Jingjing Tang, Jing Chen, Qing Xiong, Jimin Lee, Cameron Stewart, Daniel Asarnow, Jack Brown, M Alejandra Tortorici, Xiao Yang, Ye-Hui Sun, Yuan-Mei Chen, Xiao Yu, Jun-Yu Si, Peng Liu, Fei Tong, Mei-Ling Huang, Jing Li, Zheng-Li Shi, Zengqin Deng, David Veesler, Huan Yan

Journal: Cell

PubMed ID: 39922191

Doi: 10.1016/j.cell.2024.12.031

Products & Services: Codon Optimization