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CRISPR-Cas9-mediated reactivation of the uricase pseudogene in human cells prevents acute hyperuricemia

Authors: Lais de Lima Balico, Eric A Gaucher

Journal: Mol Ther Nucleic Acids

PubMed ID: 34589279

Doi: 10.1016/j.omtn.2021.08.002

Products & Services: Mammalian Expression

Blockade of Autocrine CCL5 Responses Inhibits Zika Virus Persistence and Spread in Human Brain Microvascular Endothelial Cells

Authors: Megan C Mladinich, Jonas N Conde, William R Schutt, Sook-Young Sohn, Erich R Mackow

Journal: MBio

PubMed ID: 34399621

Doi: 10.1128/mBio.01962-21

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output

Authors: Dimitris C Kanellis, Jaime A Espinoza, Asimina Zisi, Elpidoforos Sakkas, Jirina Bartkova, Anna-Maria Katsori, Johan Boström, Lars Dyrskjøt, Helle Broholm, Mikael Altun, Simon J Elsässer, Mikael S Lindström, Jiri Bartek

Journal: Sci Adv

PubMed ID: 34348895

Doi: 10.1126/sciadv.abf7561

Products & Services: Plasmid DNA Preparation

Complete and efficient conversion of plant cell wall hemicellulose into high-value bioproducts by engineered yeast

Authors: Liang Sun, Jae Won Lee, Sangdo Yook, Stephan Lane, Ziqiao Sun, Soo Rin Kim, Yong-Su Jin

Journal: Nat Commun

PubMed ID: 34404791

Doi: 10.1038/s41467-021-25241-y

Products & Services: PCR Cloning and Subcloning

The Use of CRISPR/Cas9 as a Tool to Study Human Infectious Viruses

Authors: Huafeng Lin, Gang Li, Xiangwen Peng, Aimin Deng, Lei Ye, Lei Shi, Tuanmei Wang, Jun He

Journal: Front Cell Infect Microbiol

PubMed ID: 34513721

Doi: 10.3389/fcimb.2021.590989

A [3Fe-4S] cluster and tRNA-dependent aminoacyltransferase BlsK in the biosynthesis of Blasticidin S

Authors: Xiankun Wang, Yuchun Zhao , Yaojie Gao , Xiangkun Luo , Aiqin Du , Zixin Deng , T. Mark Zabriskied , Xinyi Hea, and Ming Jiang

Journal: PNAS

PubMed ID: 34282016

Doi: 10.1073/pnas.2102318118

Products & Services: Gene Services

Chemerin/ChemR23 signaling mediates the effects of ultra-high molecular weight polyethylene wear particles on the balance between osteoblast and osteoclast differentiation

Authors: Fengchao Zhao, Dingwei Cang, Jianzhi Zhang, Li Zheng

Journal: Ann Transl Med

PubMed ID: 34430590

Doi: 10.21037/atm-21-2945

Products & Services: Molecular Biology Reagents

Immunogenicity Studies of Plant-Produced SARS-CoV-2 Receptor Binding Domain-Based Subunit Vaccine Candidate with Different Adjuvant Formulations

Authors: Konlavat Siriwattananon, Suwimon Manopwisedjaroen, Balamurugan Shanmugaraj, Eakachai Prompetchara, Chutitorn Ketloy, Supranee Buranapraditkun, Kittipan Tharakhet, Papatsara Kaewpang, Kiat Ruxrungtham, Arunee Thitithanyanont, Waranyoo Phoolcharoen

Journal: Vaccines (Basel)

PubMed ID: 34358160

Doi: 10.3390/vaccines9070744

Products & Services: Serology SARS-Cov-2 detection kits

Lipopolysaccharide Binding Protein and CD14, Cofactors of Toll-like Receptors, Are Essential for Low-Grade Inflammation-Induced Exacerbation of Cartilage Damage in Mouse Models of Posttraumatic Osteoarthritis

Authors: Yoonkyung Won, Jeong-In Yang, Seulki Park, Jang-Soo Chun

Journal: Arthritis Rheumatol

PubMed ID: 33559324

Doi: 10.1002/art.41679

Products & Services: Recombinant Proteins

Interferon-beta, interferon-gamma and their fusion interferon of Siberian tigers (Panthera tigris altaica) in China are involved in positive-feedback regulation of interferon production

Authors: Mengyao Mu, Hongjing Zhao, Yu Wang, Menghao Guo, Xiaopan Nie, Yachen Liu, Mingwei Xing