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Failure of Diphtheria Toxin Model to Induce Parkinson-Like Behavior in Mice

Authors: Lucie Valek, Irmgard Tegeder

Journal: Int J Mol Sci

PubMed ID: 34502404

Doi: 10.3390/ijms22179496

Products & Services: Endotoxin Detection & Removal System

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Authors: Juan Luis Pacheco-Garcia, Ernesto Anoz-Carbonell, Pavla Vankova, Adithi Kannan, Rogelio Palomino-Morales, Noel Mesa-Torres, Eduardo Salido, Petr Man, Milagros Medina, Athi N Naganathan, Angel L Pey

Journal: Redox Biol

PubMed ID: 34537677

Doi: 10.1016/j.redox.2021.102112

Products & Services: Mutagenesis Services

An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates

Authors: Nerea Zabaleta, Wenlong Dai, Urja Bhatt, Cécile Hérate, Pauline Maisonnasse, Jessica A Chichester, Julio Sanmiguel, Reynette Estelien, Kristofer T Michalson, Cheikh Diop, Dawid Maciorowski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Thibaut Naninck, Nidhal Kahlaoui, Julien Lemaitre, Wenbin Qi, Elissa Hudspeth, Allison Cucalon, Cecilia D Dyer, M Betina Pampena, James J Knox, Regina C LaRocque, Richelle C Charles, Dan Li, Maya Kim, Abigail Sheridan, Nadia Storm, Rebecca I Johnson, Jared Feldman, Blake M Hauser, Vanessa Contreras, Romain Marlin, Raphaël Ho Tsong Fang, Catherine Chapon, Sylvie van der Werf, Eric Zinn, Aisling Ryan, Dione T Kobayashi, Ruchi Chauhan, Marion McGlynn, Edward T Ryan, Aaron G Schmidt, Brian Price, Anna Honko, Anthony Griffiths, Sam Yaghmour, Robert Hodge, Michael R Betts, Mason W Freeman, James M Wilson, Roger Le Grand, Luk H Vandenberghe

Journal: Cell Host Microbe

PubMed ID: 34428428

Doi: 10.1016/j.chom.2021.08.002

Products & Services: Monoclonal Antibody Services

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity

Authors: Sarah C Atkinson, Steven M Heaton, Michelle D Audsley, Oded Kleifeld, Natalie A Borg

Journal: Int J Mol Sci

PubMed ID: 34445801

Doi: 10.3390/ijms22169094

Products & Services: Bacterial Expression

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

Authors: Matthew J Gorman, Nita Patel, Mimi Guebre-Xabier, Alex L Zhu, Caroline Atyeo, Krista M Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jing-Hui Tian, Dansu Yuan, Kathryn A Bowman, Bin Zhou, Sonia Maciejewski, Marisa E McGrath, James Logue, Matthew B Frieman, David Montefiori, Colin Mann, Sharon Schendel, Fatima Amanat, Florian Krammer, Erica Ollmann Saphire, Douglas A Lauffenburger, Ann M Greene, Alyse D Portnoff, Michael J Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Galit Alter

Journal: Cell Rep Med

PubMed ID: 34485950

Doi: 10.1016/j.xcrm.2021.100405

Products & Services: Insect Expression

Genome-wide identification of the MADS-box transcription factor family in autotetraploid cultivated alfalfa (Medicago sativa L) and expression analysis under abiotic stress

Authors: Xueming Dong, Hao Deng, Wenxue Ma, Qiang Zhou, Zhipeng Liu

Journal: BMC Genomics

PubMed ID: 34362293

Doi: 10.1186/s12864-021-07911-9

Products & Services: Protein Tools

Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex

Authors: Weifeng Liu, Zachary Maben, Carole Wang, Kevin C Lindquist, Manqing Li, Vinayak Rayannavar, Ilsel Lopez Armenta, Andrew Nager, Edward Pascua, Pawel K Dominik, David Oyen, Hui Wang, Rachel Carson Roach, Corey M Allan, Lidia Mosyak, Javier Chaparro-Riggers

Journal: J Biol Chem

PubMed ID: 34419446

Doi: 10.1016/j.jbc.2021.101102

Products & Services: Polyclonal Antibody Services

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

Authors: Chun Gong, Joanna A Krupka, Jie Gao, Nicholas F Grigoropoulos, George Giotopoulos, Ryan Asby, Michael Screen, Zelvera Usheva, Francesco Cucco, Sharon Barrans, Daniel Painter, Nurmahirah Binte Mohammed Zaini, Björn Haupl, Susanne Bornelöv, Igor Ruiz De Los Mozos, Wei Meng, Peixun Zhou, Alex E Blain, Sorcha Forde, Jamie Matthews, Michelle Guet Khim Tan, G A Amos Burke, Siu Kwan Sze, Philip Beer, Cathy Burton, Peter Campbell, Vikki Rand, Suzanne D Turner, Jernej Ule, Eve Roman, Reuben Tooze, Thomas Oellerich, Brian J Huntly, Martin Turner, Ming-Qing Du, Shamith A Samarajiwa, Daniel J Hodson

Journal: Mol Cell

PubMed ID: 34437837

Doi: 10.1016/j.molcel.2021.07.041

Products & Services: Polyclonal Antibody Services

Haploinsufficiency of SF3B2 causes craniofacial microsomia

Authors: Andrew T Timberlake, Casey Griffin, Carrie L Heike, Anne V Hing, Michael L Cunningham, David Chitayat, Mark R Davis, Soghra J Doust, Amelia F Drake, Milagros M Duenas-Roque, Jack Goldblatt, Jonas A Gustafson, Paula Hurtado-Villa, Alexis Johns, Natalya Karp, Nigel G Laing, Leanne Magee, Sureni V Mullegama, Harry Pachajoa, Gloria L Porras-Hurtado, Rhonda E Schnur, Jennie Slee, Steven L Singer, David A Staffenberg, Andrew E Timms, Cheryl A Wise, Ignacio Zarante, Jean-Pierre Saint-Jeannet, Daniela V Luquetti

Journal: Nat Commun

PubMed ID: 34344887

Doi: 10.1038/s41467-021-24852-9

Products & Services: Mammalian Expression

Structure of autoinhibited Akt1 reveals mechanism of PIP-mediated activation

Authors: Linda Truebestein, Harald Hornegger, Dorothea Anrather, Markus Hartl, Kaelin D Fleming, Jordan T B Stariha, Els Pardon, Jan Steyaert, John E Burke, Thomas A Leonard

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34385319

Doi: 10.1073/pnas.2101496118

Products & Services: Proteins, Expression, Isolation and Analysis

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