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Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator

Authors: Demeng Sun, Xiang Li, Qingning Yuan, Yuanxia Wang, Pan Shi, Huanhuan Zhang, Tao Wang, Wenjing Sun, Shenglong Ling, Yuanchun Liu, Jinglin Lai, Wenqin Xie, Wanchao Yin, Lei Liu, H. Eric Xu, Changlin Tian

Journal: Cell Res

PubMed ID: 40118988

Doi: doi.org/10.1038/s41422-025-01095-7

Products & Services: Antibody Modification and Purification Services Protein and Antibody Isolation

A Functional 3D Biomimetic Osteon Accelerates Bone Regeneration

Authors: Chenxu Zhu, Zexi Li, Xubin Qiu, Baizhen Zhao, Huan Wang, Lijie Wang, Ming Zhuang, Jinbo Liu, Fengxuan Han, Bin Li

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.202500603

Products & Services: Protein and Antibody Isolation

Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide–HLA-I Fusion Protein by Armoring with Mutein IFNα

Authors: Douwe Freerk Samplonius , Anne Paulien van Wijngaarden , Lisanne Koll , Xiurong Ke , Wijnand Helfrich

Journal: Int J Mol Sci

PubMed ID: 40243928

Doi: ijms26073178

Products & Services: Gene Synthesis

Antigen-presenting cancer associated fibroblasts enhance antitumor immunity and predict immunotherapy response

Authors: Junquan Song, Rongyuan Wei, Chenchen Liu, Zhenxiong Zhao, Xuanjun Liu, Yanong Wang, Fenglin Liu, Xiaowen Liu

Journal: Nature Communications

PubMed ID: 40038297

Doi: 10.1038/s41467-025-57465-7

Products & Services: Peptide Services

Oxytocin induces embryonic diapause

Authors: Jessica L Minder, Sarah B Winokur, Janaye Stephens, Jie Tong, Naomi L Cassel, Luisa Schuster, Habon A Issa, Michael Cammer, Latika Khatri, Gaia Moisan, Maria Alvarado-Torres, Orlando Aristizábal, Youssef Z Wadghiri, Sang Yong Kim, Silvana Valtcheva, Catherine Pei-Ju Lu, Moses V Chao, Robert C Froemke

Journal: SCIENCE ADVANCES

PubMed ID: 40043121

Doi: 10.1126/sciadv.adt1763

Products & Services: Peptide Synthesis

Structural basis for the activation of plant bunyavirus replication machinery and its dual-targeted inhibition by ribavirin

Authors: Jia Li, Lei Cao, Yaqian Zhao, Jinghan Shen, Lei Wang, Mingfeng Feng, Min Zhu, Yonghao Ye, Richard Kormelink, Xiaorong Tao, Xiangxi Wang

Journal: Nat Plants

PubMed ID: 40044941

Doi: 10.1038/s41477-025-01940-y

Authors: Jingjing Wang, Yong Ma, Zimu Li, Hang Yuan, Banghui Liu, Zexuan Li, Mengzhen Su, Gul Habib, Yutong Liu, Lutang Fu, Peiyi Wang, Mei Li, Jun He, Jing Chen, Peng Zhou, Zhengli Shi, Xinwen Chen, Xiaoli Xiong

Journal: SCIENCE ADVANCES

PubMed ID: 40085715

Doi: 10.1126/sciadv.adr8772

Products & Services: Codon Optimization

Developing Quorum Sensing-Based Collaborative Dynamic Control System in Halomonas TD01

Authors: Yi-Na Lin, Yu-Xi Li, Ye Zheng, Yi-Hao Deng, Kai-Xuan Liu, Yue Gan, Hao Li, Jun Wang, Jia-Wen Peng, Rui-Zhe Deng, Huai-Ming Wang, Hui Wang, Jian-Wen Ye

Journal: Advanced Science

PubMed ID: 40091435

Doi: 10.1002/advs.202408083

Products & Services: Protein Electrophoresis and Western

The conductance of KCNQ2 and its pathogenic variants is determined by individual subunit gating

Authors: Andy Hinojo-Perez, Jodene Eldstrom, Ying Dou, Allan Marinho-Alcara, Michaela A Edmond, Alicia de la Cruz, Marta E Perez Rodriguez, Maykelis Diaz-Solares, Derek M Dykxhoorn, David Fedida, Rene Barro-Soria

Journal: SCIENCE ADVANCES

PubMed ID: 40043113

Doi: 10.1126/sciadv.adr7012

Products & Services: Gene Synthesis

Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

Authors: Lanfang Ren, Zeda Zhao, Yuqing Chao, Panting Yu, Zhoufang Mei, Bing Du, Yiyun Cheng

Journal: Advanced Science

PubMed ID: 40056044

Doi: 10.1002/advs.202500844