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Cell trajectory modulation: rapid microfluidic biophysical profiling of CAR T cell functional phenotypes

Authors: Kerwin Kwek Zeming, Kai Yun Quek, Wei-Xiang Sin, Denise Bei Lin Teo, Ka-Wai Cheung, Chin Ren Goh, Faris Kairi, Elizabeth Lee, Francesca Lorraine Wei Inng Lim, Michaela Su-Fern Seng, Shui Yen Soh, Michael E Birnbaum, Jongyoon Han

Journal: Nature Communications

PubMed ID: 40404664

Doi: 10.1038/s41467-025-59789-w

Products & Services: Plasmid DNA Preparation

Modular deregulation of central carbon metabolism for efficient xylose utilization in Saccharomyces

Authors: Xiaowei Li, Yanyan Wang, Xin Chen, Leon Eisentraut, Chunjun Zhan, Jens Nielsen, Yun Chen

Journal: Nature Communications

PubMed ID: 40379631

Doi: 10.1038/s41467-025-59966-x

Products & Services: Gene Synthesis

FOXA2 promotes metastatic competence in small cell lung cancer

Authors: Kenta Kawasaki, Sohrab Salehi, Yingqian A Zhan, Kevin Chen, Jun Ho Lee, Eralda Salataj, Hong Zhong, Parvathy Manoj, Dennis Kinyua, Barbara P Mello, Harsha Sridhar, Sam E Tischfield, Irina Linkov, Nicholas Ceglia, Matthew Zatzman, Eliyahu Havasov, Neil J Shah, Fanli Meng, Brian Loomis, Umesh K Bhanot, Esther Redin, Elisa de Stanchina, Pierre-Jacques Hamard, Richard P Koche, Andrew McPherson, Álvaro Quintanal-Villalonga, Sohrab P Shah, Joan Massagué, Charles M Rudin

Journal: Nature Communications

PubMed ID: 40419484

Doi: 10.1038/s41467-025-60141-5

A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA

Authors: Jonas Aretz, Gayathri Jeyasankar, Anna Salerno-Kochan, Maren Thomsen, Gabriel Thieulin-Pardo, Tasir Haque, Edith Monteagudo, Dan Felsenfeld, Michael Finley, Thomas F Vogt, Julien Boudet, Brinda C Prasad

Journal: Nature Communications

PubMed ID: 40368883

Doi: 10.1038/s41467-025-59324-x

Products & Services: Gene Synthesis

Structural basis of phosphorylation-independent nuclear import of CIRBP by TNPO3

Authors: Qishun Zhou, Theo Sagmeister, Saskia Hutten, Benjamin Bourgeois, Tea Pavkov-Keller, Dorothee Dormann, Tobias Madl

Journal: Nature Communications

PubMed ID: 40360518

Doi: 10.1038/s41467-025-59802-2

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Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease

Authors: Meng Jiang, Qingqing Li, Jianhui Chen, Ruochong Li, Jun Yao, Yong Hu, Haizheng Zhang, Lixin Cai, Maoguo Luo, Yu Sun, Wenwen Zeng

Journal: Advanced Science

PubMed ID: 40349168

Doi: 10.1002/advs.202417733

Products & Services: Protein and Antibody Isolation

HR eye & MMR eye: one-day assessment of DNA repair-defective tumors eligible for targeted therapy

Authors: Shinta Saito, Shingo Kato, Usaki Arai, Atsuki En, Jun Tsunezumi, Taichi Mizushima, Kensuke Tateishi, Noritaka Adachi

Journal: Nature Communications

PubMed ID: 40355434

Doi: 10.1038/s41467-025-59462-2

Products & Services: Gene Synthesis

Teleost GSDMEc regulates GSDMEa-mediated pyroptos

Authors: Hang Xu, Meng Wu, Yujian Wang, Yaoming Jiao, Yuan Chen, Zihao Yuan, Li Sun

Journal: J Adv Res

PubMed ID: 40210150

Doi: doi.org/10.1016/j.jare.2025.04.007

Products & Services: Protein and Antibody Isolation

The ribosome-associated quality control factor TCF25 imposes K48 specificity on Listerin-mediated ubiquitination of nascent chains by binding and specifically orienting the acceptor ubiquitin

Authors: Irina S Abaeva, Alexander G Bulakhov, Christopher U T Hellen, Tatyana V Pestova

Journal: Genes Dev

PubMed ID: 40169231

Doi: 10.1101/gad.352389.124

Products & Services: Mutagenesis Services Custom Vector Construction Protein and Antibody Isolation Custom Vector Construction Mutagenesis Services Protein and Antibody Reagents

BARD1-mediated stabilization of METTL14 promotes retinal neovascularization by m6A-modifying MXD1 mRNA on a YTHDF2-dependent manner

Authors: Xianyang Liu, Shuhao Zeng, Jiayu Meng, Qian Zhou, Fan Cao, Baorui Chu, Chao Wu, Yakun Wang, Hui Feng, Xiaorui Bi, Xinyuan Chen, Wenxian Yang, Meng Tian, Hui Yang, Ke Hu, Shengping Hou

Journal: Theranostics

Doi: 10.7150/thno.110122

Products & Services: Catalog Antibodies