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A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

Authors: Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, Yingxiao Zhu, Xiaodong Yan, Hui Shi, François Ferron, Bruno Canard

Journal: Nat Commun

PubMed ID: 35110538

Doi: 10.1038/s41467-022-28113-1

Products & Services: Custom DNA/RNA Oligos

Lack of Induction of RBD-Specific Neutralizing Antibodies despite Repeated Heterologous SARS-CoV-2 Vaccination Leading to Seroconversion and Establishment of T Cell-Specific Memory in a Patient in Remission of Multiple Myeloma

Authors: Bernhard Kratzer, Doris Trapin, Pia Gattinger, Teresa Oberhofer, Al Nasar Ahmed Sehgal, Petra Waidhofer-Söllner, Arno Rottal, Ulrike Körmöczi, Katharina Grabmeier-Pfistershammer, Gerhard H Kopetzky, Franz Tischer, Rudolf Valenta, Winfried F Pickl

Journal: Vaccines (Basel)

PubMed ID: 35335006

Doi: 10.3390/vaccines10030374

Products & Services: Proteins, Expression, Isolation and Analysis

Myricetin reverses epithelial-endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1

Authors: Ming Wang, Shanfa Ren, Zhun Bi, Liang Zhang, Mengqi Cui, Ronghao Sun, Jiali Bao, Dandi Gao, Bo Yang, Xiaoping Li, Mingjiang Li, Ting Xiao, Hong-Gang Zhou, Cheng Yang

Journal: Phytother Res

PubMed ID: 35229382

Doi: 10.1002/ptr.7427

Products & Services: Stable Cell Lines

Extended β-Strands Contribute to Reversible Amyloid Formation

Authors: Kevin A Murray, Declan Evans, Michael P Hughes, Michael R Sawaya, Carolyn J Hu, Kendall N Houk, David Eisenberg

Journal: ACS Nano

PubMed ID: 35132852

Doi: 10.1021/acsnano.1c08043

Products & Services: Catalog Peptides

Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors

Authors: Nishanth Belugali Nataraj, Ashish Noronha, Joo Sang Lee, Soma Ghosh, Harsha Raj Mohan Raju, Arunachalam Sekar, Binyamin Zuckerman, Moshit Lindzen, Emilio Tarcitano, Swati Srivastava, Michael Selitrennik, Ido Livneh, Diana Drago-Garcia, Oscar Rueda, Carlos Caldas, Sima Lev, Tamar Geiger, Aaron Ciechanover, Igor Ulitsky, Rony Seger, Eytan Ruppin, Yosef Yarden

Journal: Cell Rep

PubMed ID: 35196484

Doi: 10.1016/j.celrep.2022.110418

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Blockage of NDUFB9‑SCD1 pathway inhibits adipogenesis

Authors: Shenglong Zhu, Jingwei Zhang, Wei Wang, Xuan Jiang, Yong Q Chen

Journal: J Physiol Biochem

PubMed ID: 35122619

Doi: 10.1007/s13105-022-00876-7

Products & Services: Recombinant Proteins Plasmid DNA Preparation

Omicron adopts a different strategy from Delta and other variants to adapt to host

Authors: Xiaohong Du , Haijun Tang , Long Gao , Zhao Wu , Fang Meng , Ruhong Yan , Shigang Qiao, Jianzhong An , Chen Wang , F Xiao-Feng Qin