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页码: 607/5143 每页显示数量

Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold

Authors: Jingjing Chen, Huixin He, Aihuan Wei, Yalei Li, Gang Cheng, Hui Qin, Hanyue Zhong, Hongchun Liu, Meiyu Geng, Aijun Shen, Youhong Hu

Journal: Eur J Med Chem

PubMed ID: 35395439

Doi: 10.1016/j.ejmech.2022.114259

Products & Services: Proteins, Expression, Isolation and Analysis

Rapid Exchange of Stably Bound Protein and DNA Cargo on a DNA Origami Receptor

Authors: James W P Brown, Rokiah G Alford, James C Walsh, Richard E Spinney, Stephanie Y Xu, Sophie Hertel, Jonathan F Berengut, Lisanne M Spenkelink, Antoine M van Oijen, Till Böcking, Richard G Morris, Lawrence K Lee

Journal: ACS Nano

PubMed ID: 35316035

Doi: 10.1021/acsnano.2c00699

Products & Services: Custom Vector Construction

Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

Authors: Ruixue Wang, Saori Suzuki, Johnathan D Guest, Brigitte Heller, Maricar Almeda, Alexander K Andrianov, Alexander Marin, Roy A Mariuzza, Zhen-Yong Keck, Steven K H Foung, Abdul S Yunus, Brian G Pierce, Eric A Toth, Alexander Ploss, Thomas R Fuerst

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35263223

Doi: 10.1073/pnas.2112008119

Products & Services: PCR Cloning and Subcloning

In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes

Authors: Kiran Kumar, Mathew Sebastiao, Alexandre A Arnold, Steve Bourgault, Dror E Warschawski, Isabelle Marcotte

Journal: Biophys J

PubMed ID: 35278426

Doi: 10.1016/j.bpj.2022.03.009

Products & Services: Peptide Synthesis

Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone

Authors: Ziling Ye, Yanglei Huang, Bin Shi, Zilei Xiang, Zhu Tian, Man Huang, Liangliang Wu, Zixin Deng, Kun Shen, Tiangang Liu

Journal: Metab Eng

PubMed ID: 35296429

Doi: 10.1016/j.ymben.2022.03.005

Products & Services: PCR and Cloning

Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH

Authors: Alena Stsiapanava, Chenrui Xu, Shunsuke Nishio, Ling Han, Nao Yamakawa, Marta Carroni, Kathryn Tunyasuvunakool, John Jumper, Daniele de Sanctis, Bin Wu, Luca Jovine

Journal: Nat Struct Mol Biol

PubMed ID: 35273390

Doi: 10.1038/s41594-022-00729-3

Products & Services: Mutant Libraries

MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity

Authors: Thilini S Munasinghe, Megan R Edwards, Sofiya Tsimbalyuk, Olivia A Vogel, Kate M Smith, Murray Stewart, Justin K Foster, Loretta A Bosence, David Aragão, Justin A Roby, Christopher F Basler, Jade K Forwood

Journal: Nat Commun

PubMed ID: 35338144

Doi: 10.1038/s41467-022-28851-2

Products & Services: Bacterial Expression

Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer

Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis

Journal: Nat Commun

PubMed ID: 35256598

Doi: 10.1038/s41467-022-28741-7

Products & Services: Catalog Peptides

The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist

Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau

Journal: PLoS Pathog

PubMed ID: 35271688

Doi: 10.1371/journal.ppat.1010355

Products & Services: Custom Vector Construction

Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections

Authors: Melissa C Remmel, Sabrina M Coyle, Mark W Eshoo, Timothy E Sweeney, David C Rawling

Journal: Clin Chem

PubMed ID: 35134876

Doi: 10.1093/clinchem/hvab275

Products & Services: Mammalian Expression

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