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页码: 34/5236 每页显示数量

Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against nonsmall cell lung cancer

Authors: Jia-Hao Tao, Jun Zhang, Chun-Yan Tang, Jia-Xi Duan, Wen-Jing Zhong, Chen-Yu Zhang, Yu-Biao Liu, Jin Ling, Hua-Shun Li, Yong Zhou, Cha-Xiang Guan

Journal: Cancer gene therapy

PubMed ID: 40913086

Doi: 10.1038/s41417-025-00957-x

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Reinforced plant-derived lipid nanoparticles for oral precise epigenome editing in colonic diseases

Authors: Qiang Gao, Yunxia Gao, Yingui Cao, Haiting Xu, Ya Ma, Menghang Zu, Qiang Yang, Kun Yang, Zhenhua Zhu, Chao Liu, Xiaoxiao Shi, Rui L Reis, Subhas C Kundu, Shengyun Ma, Hesong Han, Bo Xiao

Journal: SCIENCE ADVANCES

PubMed ID: 41004579

Doi: 10.1126/sciadv.adw9275

Products & Services: Catalog Gene Editing

Systematic profiling reveals betaine as an exercise mimetic for geroprotection

Authors: Lingling Geng, Jiale Ping, Ruochen Wu, Haoteng Yan, Hui Zhang, Yuan Zhuang, Taixin Ning, Jun Wang, Chuqian Liang, Jiachen Zhang, Qingqing Chu, Jing Zhang, Yifan Wen, Yaobin Jing, Shuhui Sun, Qin Qiao, Qian Zhao, Qianzhao Ji, Shuai Ma, Yusheng Cai, Yandong Zheng, Zhiran Zou, Zhiqing Diao, Mingheng Li, Hao Zhang, Jianli Hu, Liangzheng Fu, Wang Kang, Ruijun Bai, Hongkai Zhao, Sheng Zhang, Yingjie Ding, Jinghui Lei, Wei Wang, Yun Ji, Bo Gou, Guoqiang Sun, Jian Yin, Pengze Yan, Hao Li, Zehua Wang, Shikun Ma, Zunpeng Liu, Hezhen Shan, Qiaoran Wang, Tianling Cao, Shanshan Yang, Cui Wang, Ping Yang, Yanling Fan, Yanxia Ye, Jinghao Hu, Mengmeng Jiang, Ye Wang, Kan Liu, Yujing Li, Yuanxiang Li, Jingyi Li, Weimin Ci, Zi-Bing Jin, Xiaobing Fu, Xu Zhang, Guoguang Zhao, Juan Carlos Izpisua Belmonte, Si Wang, Moshi Song, Weiqi Zhang, Jing Qu, Guang-Hui Liu

Journal: Cell

PubMed ID: 40570836

Doi: 10.1016/j.cell.2025.06.001

Products & Services: Synthetic Guide RNA

RING-Between-RING-Type E3 Ligase Ariadne-Like Protein 8 Negatively Regulates Plant Virus Infection by Targeting a Viral Movement Protein

Authors: Wenli Li, Chenchen Zhong, Jiangning Duan, Changyi Zhan, Zhaolei Li, Xinyu Zhang, Dingliang Zhang, Deshui Liu, Zhiyan Wen, Xiaofei Zhao, Meng Yang, Dawei Li, Yongliang Zhang

Journal: Advanced Science

PubMed ID: 40908568

Doi: 10.1002/advs.202509942

Multiple myeloma associated long non-coding RNA PLUM confers chemoresistance by enhancing PRC2 mediated UPR pathway activation

Authors: Kamalakshi Deka, Jean-Michel Carter, Akash Bahai, Daniel Aron Ang, Nicholas Sim, Hooi Yan Chong, Guan Hwee Bernard Lee, Suet Mien Tan, Wee Joo Chng, Dennis Kappei, Yinghui Li

Journal: Nature Communications

PubMed ID: 40890111

Doi: 10.1038/s41467-025-63256-x.

Products & Services: Gene Services

Structural insights into proprotein convertase activation facilitate the engineering of highly specific furin inhibitors

Authors: Rupert Klaushofer, Konstantin Bloch, Luisa Susanna Eder, Simone Marzaro, Mario Schubert, Eva Böttcher-Friebertshäuser, Hans Brandstetter, Sven O Dahms

Journal: Nature Communications

PubMed ID: 40897699

Doi: 10.1038/s41467-025-63479-y.

Ultrastrong Staphylococcus aureus adhesion to human skin: Calcium as a key regulator of noncovalent interactions

Authors: Constance Chantraine, Priscila S F C Gomes, Marion Mathelié-Guinlet, Diego E B Gomes, Zhiyong Zheng, Julianne Clowry, Mary B Turley, Alan D Irvine, Joan A Geoghegan, Rafael C Bernardi, Yves F Dufrêne

Journal: SCIENCE ADVANCES

PubMed ID: 40901964

Doi: 10.1126/sciadv.adu7457

The kinetics of nsp7-11 polyprotein processing and impact on complexation with nsp16 among human coronaviruses

Authors: Kira Schamoni-Kast, Boris Krichel, Tomislav Damjanović, Fatema-Aqila Said, Thomas Kierspel, Sibel Toker, Charlotte Uetrecht

Journal: Nature Communications

PubMed ID: 40925907

Doi: 10.1038/s41467-025-61554-y.

Products & Services: Gene Services

UHRF1 Controls the Timing of RAD51 Removal During DNA Damage Repair Through Suppressing RFWD3

Authors: Guangxue Liu, Kaiyan Huang, Shiyao Liu, Ziyu Sheng, Pumin Zhang

Journal: Advanced Science

PubMed ID: 40940676

Doi: 10.1002/advs.202509901

M2e peptide libraries were synthesized on the basis of the M2e-CS peptide, N-SLLTEVETPIRNEWGCRCNDSSD, and purchased from GenScript.

Authors: Teha Kim, Lynn Bimler, Sydney L Ronzulli, Amber Y Song, Scott K Johnson, Cheryl A Jones, S Mark Tompkins, Silke Paust

Journal: SCIENCE ADVANCES

PubMed ID: 40929256

Doi: 10.1126/sciadv.adx3505

Products & Services: Peptide Services