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DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage

Authors: Zihui Yan, Guanjin Qu, Xin Chen, Gang Zheng & Huaming Wu

Journal: Nature Communications

PubMed ID: 41102205

Doi: 10.1038/s41467-025-64230-3

Mechanism-based peroxiredoxin 3 inhibitors exploit a covalent warhead for cancer therapy

Authors: Kimberly J Nelson, Terrence L Smalley Jr, Terri Messier, Rajesh Gumpena, Uma Gandhi, Stephanie Milczarek, Aida Habibovic, Hattie Hoffman, Victoria Gibson, Robert J Hondal, W Todd Lowther, Brian Cunniff

Journal: SCIENCE ADVANCES

PubMed ID: 41171914

Doi: 41171914

The nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection

Authors: Tai-Ting Woo, Yuka Takeo, Mara C Harwood, Ethan T Houck, Daniel DiMaio, Billy Tsai

Journal: SCIENCE ADVANCES

PubMed ID: 41124246

Doi: 10.1126/sciadv.adz6792

DLFea4AMPGen de novo design of antimicrobial peptides by integrating features learned from deep learning models

Authors: Han Gao, Feifei Guan, Boyu Luo, Dongdong Zhang, Wei Liu, Yuying Shen, Lingxi Fan, Guoshun Xu, Yuan Wang, Tao Tu, Ningfeng Wu, Bin Yao, Huiying Luo, Yue Teng, Jian Tian, Huoqing Huang

Journal: Nature Communications

PubMed ID: 41093853

Doi: 10.1038/s41467-025-64378-y

A human-specific regulatory mechanism revealed in a pre-implantation model

Authors: Raquel Fueyo, Sicong Wang, Olivia J. Crocker, Tomek Swigut, Hiromitsu Nakauchi & Joanna Wysocka

Journal: Nature

PubMed ID: 41034587

Doi: 10.1038/s41586-025-09571-1

Discovery of a Serine-Directed Chemical Reaction for Site-Specific Protein Modification via Phage Display Screening

Authors: Yingjie Lei, Kai Zhao, Mengzhun Guo, Liang Guo, Jinfeng Chen, Mengjiao Li, Dandan Liu, Kai Chen, Jiahao Mei, Tian Li, Bing Yang, Jing Huang, Bobo Dang

Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PubMed ID: 41108661

Doi: doi.org/10.1002/anie.202514412

Products & Services: Protein and Antibody Isolation

ROS-triggered self-assembling peptide hydrogel combining bacterial entrapment and intracellular penetration for Salmonella Typhimurium-induced enteritis therapy

Authors: Wenwen Meng, Hao Yang, Wenqian Zhang, Xueyan Li, Jiajun Sun, Ting Hu, Wei Li, Yaohong Zhu, Yong Wang, Xi Ma, Guiyan Yang, Jiufeng Wang

Journal: Chemical Engineering Journal

Doi: doi.org/10.1016/j.cej.2025.169392

Products & Services: Peptide Synthesis

Noncanonical target-strand cytosine base editing via engineered Un1Cas12f1 platform

Authors: Ziguo Song, Junfan Guo, Zhanqing Fan, Shuhong Huang, Guanglei Li, Zichang Zhao, Bingchun Chen, Shisheng Huang, Wenxin Zheng, Yinghui Wei, Yulin Chen, Xingxu Huang, Jianghuai Liu, Lina Wu, Xiaolong Wang

Journal: Nature Communications

PubMed ID: 41152217

Doi: 10.1038/s41467-025-64562-0

Products & Services: Plasmid DNA Preparation

Metal fluoride nanoregulators reverse therapeutic resistance via stemness remodeling to trigger pyroptosis for chemoimmunotherapy

Authors: Shumin Sun, Nailin Yang, Jihu Nie, Linzhu Zhang, Di Wang, Xingwei Sun, Yong Jin, Liang Cheng

Journal: Bioactive Materials

PubMed ID: 41211577

Doi: 10.1016/j.bioactmat.2025.10.011

Products & Services: Protein and Antibody Isolation

Non-canonical dihydrolipoyl transacetylase promotes chemotherapy resistance via mitochondrial tetrahydrofolate signaling

Authors: Jung Seok Hwang, JiHoon Kang, Jaehyun Kim, Kiyoung Eun, Sophia West, Hannah E Bacho, Vanessa Avalos, Sydney Shuff, Dong M Shin, Nabil F Saba, Kelly R Magliocca, Cheng-Kui Qu, Haian Fu, Suresh S Ramalingam, Andrey A Ivanov, Taro Hitosugi, Sumin Kang

Journal: Nature Communications

PubMed ID: 41062483

Doi: 10.1038/s41467-025-63892-3