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A novel ex vivo assay to evaluate functional effectiveness of Plasmodium vivax transmission blocking vaccine using Pvs25 transgenic P. berghei

Authors: Yi Cao, Clifford T H Hayashi, Nirbhay Kumar

Journal: J Infect Dis

PubMed ID: 38408353

Doi: 10.1093/infdis/jiae102

Products & Services: Gene Synthesis

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD

Authors: Marian Hruska-Plochan, Vera I Wiersma, Katharina M Betz, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma , Laura De Vos, Karl Frontzek , Adriano Aguzzi, Tammaryn Lashley , Mark D Robinson, Theofanis Karayannis, Martin Mueller, Andreas Hierlemann 4, Magdalini Polymenidou 13

Journal: Nature

PubMed ID: 38355792

Doi: 10.1038/s41586-024-07042-7

Products & Services: Gene Synthesis

HIV coinfection exacerbates HBV-induced liver fibrogenesis through a HIF-1α- and TGF-β1-dependent pathway

Authors: Min Xu , Charlotte Warner, Xiaoqiong Duan, Zhimeng Cheng, Andre J Jeyarajan, Wenting Li, Yongtao Wang , Tuo Shao , Shadi Salloum , Pei-Jer Chen , Xu Yu , Raymond T Chung , Wenyu Lin

Journal: J Hepatol

PubMed ID: 38311121

Doi: 10.1016/j.jhep.2024.01.026

Products & Services: Gene Synthesis

Unraveling the Catalytic Mechanism of Taxadiene-5α-hydroxylase from Crystallography and Computational Analyses

Authors: Xitong Song, Qian Wang, Xiaoxi Zhu, Wenhan Fang, Xiaonan Liu, Chao Shi, Zhenzhan Chang, Huifeng Jiang, and Binju Wang

Journal: ACS Catal

Doi: doi.org/10.1021/acscatal.3c05807

Products & Services: Gene Synthesis

Covalent bicyclization of protein complexes yields durable quaternary structures

Authors: George H Hutchins, Sebastian Kiehstaller, Pascal Poc, Abigail H Lewis, Jisun Oh, Raya Sadighi, Nicholas M Pearce, Mohamed Ibrahim, Ivana Drienovská, Anouk M Rijs, Saskia Neubacher, Sven Hennig, Tom N Grossmann

Journal: Chem

PubMed ID: 38344167

Doi: 10.1016/j.chempr.2023.10.003

Products & Services: Protein and Antibody Isolation

Neuroprotective effects of annexin A1 tripeptide in rats with sepsis-associated encephalopathy

Authors: Qiao Cui, Nannan Qin, Yonghan Zhang, Yanmei Miao, Leiyu Xie, Xinglong Ma, Zhiquan Zhang, Peng Xie

Journal: Biotechnol Appl Biochem

PubMed ID: 38409880

Doi: 10.1002/bab.2569

Products & Services: Peptide Synthesis

The CRL5–SPSB3 ubiquitin ligase targets nuclear cGAS for degradation

Authors: Pengbiao Xu , Ying Liu , Chong Liu , Baptiste Guey , Lingyun Li , Pauline Melenec , Jonathan Ricci , Andrea Ablasser

Journal: Nature

PubMed ID: 38418882

Doi: 10.1038/s41586-024-07112-w

Products & Services: Antibody Modification and Purification Services

The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression

Authors: Qiankun Wang, Kolin M Clark, Ritudhwaj Tiwari, Nagarajan Raju, Gregory K Tharp, Jeffrey Rogers, R Alan Harris, Muthuswamy Raveendran, Steven E Bosinger, Tricia H Burdo, Guido Silvestri, Liang Shan

Journal: Cell

PubMed ID: 38428396

Doi: 10.1016/j.cell.2024.01.048

Products & Services: Gene Synthesis

Molecular dissection of an intronic enhancer governing cold-induced expression of the vacuolar invertase gene in potato

Authors: Xiaobiao Zhu , Airu Chen, Nathaniel M Butler, Zixian Zeng, Haoyang Xin , Lixia Wang , Zhaoyan Lv, Dani Eshel, David S Douches, Jiming Jiang

Journal: Cell

PubMed ID: 38374801

Doi: 10.1093/plcell/koae050

Products & Services: Gene Synthesis

Insertion of a FLAG-tag sequence at the end of exon 9 of the TBX5 gene in three induced pluripotent stem cell lines (DHMi004-A-4, DHMi004-A-5, DHMi004-A-6) by CRISPR/Cas9 technology

Authors: Harald Lahm, Niraj K Singh, Irina Gottmann, Stefanie A Doppler, Elda Dzilic, Heike Preisler, Stephanie Schneider, Rüdiger Lange, Markus Krane, Martina Dreßen

Journal: Cell Research

PubMed ID: 38100916

Doi: 10.1016/j.scr.2023.103261

Products & Services: Plasmid DNA Preparation