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The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma

Authors: Stephan Spahn, Fabian Kleinhenz, Ekaterina Shevchenko, Aaron Stahl, Yvonne Rasen, Christine Geisler, Kristina Ruhm, Marion Klaumuenzer, Thales Kronenberger, Stefan A Laufer, Holly Sundberg-Malek, Khac Cuong Bui, Marius Horger, Saskia Biskup, Klaus Schulze-Osthoff, Markus Templin, Nisar P Malek, Antti Poso, Michael Bitzer

Journal: Nat Commun

PubMed ID: 38346946

Doi: 10.1038/s41467-024-45247-6

Products & Services: Molecular Biology Reagents

Autoinhibition and activation of myosin VI revealed by its cryo-EM structure

Authors: Fengfeng Niu, Lingxuan Li, Lei Wang, Jinman Xiao, Shun Xu, Yong Liu, Leishu Lin, Cong Yu, Zhiyi Wei

Journal: Nat Commun

PubMed ID: 38331992

Doi: 10.1038/s41467-024-45424-7

Products & Services: Protein and Antibody Isolation

Cutting Edge: Characterization of Low Copy Number Human Angiotensin-Converting Enzyme 2-Transgenic Mice as an Improved Model of SARS-CoV-2 Infection

Authors: Christine M Bradshaw, Teodora Georgieva, Trevor N Tankersley, Tama Taylor-Doyle, Larry Johnson, Jennifer L Uhrlaub, David Besselsen, Janko Ž Nikolich

Journal: J Immunol

PubMed ID: 38197714

Doi: 10.4049/jimmunol.2300591

Products & Services: Protein and Antibody Isolation

Enhancing CAR Macrophage Efferocytosis Via Surface Engineered Lipid Nanoparticles Targeting LXR Signaling

Authors: Skylar T Chuang, Joshua B Stein, Sarah Nevins, Cemile Kilic Bektas, Hye Kyu Choi, Wan-Kyu Ko, Hyunjun Jang, Jihun Ha, Ki-Bum Lee

Journal: Adv Mater

PubMed ID: 38353580

Doi: 10.1002/adma.202308377

Products & Services: Protein and Antibody Isolation

Molecular Characterization of Plant Volatile Compound Interactions with Odorant-Binding Proteins

Authors: Qi Qian, Xin Guo, Lingjie Wu, Jiarong Cui, Huiying Gao, Yajun Yang, Hongxing Xu, Zhongxian Lu, Pingyang Zhu

Journal: Plants (Basel)

PubMed ID: 38498446

Doi: 10.3390/plants13040479

Products & Services: Protein and Antibody Isolation

Cytokine responses to major human Cytomegalovirus antigens in mouse model

Authors: Sahar Essa, Hussain A Safar, Raj Raghupathy

Journal: Cytokine

PubMed ID: 38359558

Doi: 10.1016/j.cyto.2024.156546

Products & Services: Protein and Antibody Isolation

Distribution analysis of TRH in Bactrocera dorsalis using a CRISPR/Cas9-mediated reporter knock-in strain

Authors: Feiyue Teng, Fengyi Guo, Jimei Feng, Yongyue Lu, Yixiang Qi

Journal: Insect Mol Biol

PubMed ID: 38411032

Doi: 10.1111/imb.12901

Products & Services: Custom DNA/RNA Oligos

Precise Engineering of Growth Factor Presentation Using Extracellular Microenvironment-Mimicking Microfluidic Microparticles

Authors: Mohammad Mahdi Hasani-Sadrabadi, Weihao Yuan, Luiza de Almeida Queiroz Ferreira, Zeyang Liu, Jun Shen, Patricia Sarrión, Fatemeh Sharifi, Atefeh Malek-Khatabi, Erfan Dashtimoghadam, Bo Yu, Sahar Ansari, Alireza Moshaverinia

Journal: ACS Biomater Sci Eng

PubMed ID: 38347681

Doi: 10.1021/acsbiomaterials.3c01922

Products & Services: Catalog Peptides

Arabidopsis thaliana RHAMNOSE 1 condensate formation drives UDP-rhamnose synthesis

Authors: Sterling Field, Yanniv Dorone, Will P Dwyer, Jack A Cox, Dan Raba, John Froehlich, Madison Blea, Olivia M S Carmo, Ian S Wallace, Renee Hastings, Steven Boeynaems, Seung Y Rhee

Journal: biorxiv

PubMed ID: 38464008

Doi: 10.1101/2024.02.15.580454

Products & Services: Custom Vector Construction

Tubule-specific cyclin-dependent kinase 12 knockdown potentiates kidney injury through transcriptional elongation defects

Authors: Yi-Lin Zhang, Tao-Tao Tang, Wei-Jie Ni, Zhong-Tang Li, Liang-Yun-Zi Jiang, Yao Wang, Xuan Zhou, Jing-Yuan Cao, Qing Yin, Wei Jiang, Ya-Jie Zhao, Wei-Hua Gan, Ai-Qing Zhang, Zuo-Lin Li, Yi Wen, Lin-Li Lv, Bi-Cheng Liu, Bin Wang

Journal: Int J Biol Sci

PubMed ID: 38481813

Doi: 10.7150/ijbs.90872

Products & Services: Gene Synthesis