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Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase

Authors: Julia Lederhofer, Yaroslav Tsybovsky, Lam Nguyen, Julie E Raab, Adrian Creanga, Tyler Stephens, Rebecca A Gillespie, Hubza Z Syeda, Brian E Fisher, Michelle Skertic , Christina Yap, Andrew J Schaub, Reda Rawi, Peter D Kwong, Barney S Graham, Adrian B McDermott , Sarah F Andrews , Neil P King , Masaru Kanekiyo

Journal: Immunity

PubMed ID: 38430907

Doi: 10.1016/j.immuni.2024.02.003

Products & Services: Gene Synthesis

Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks

Authors: Carla A Jaeger-Ruckstuhl Yun Lo, Elena Fulton , Olivia G Waltner, Tamer B Shabaneh , Sylvain Simon , Pranav V Muthuraman , Colin E Correnti , Oliver J Newsom , Ian A Engstrom , Sami B Kanaan , Shruti S Bhise , Jobelle M C Peralta , Raymond Ruff , Jason P Price , Sylvia M Stull , Andrew R Stevens , Grace Bugos, Mitchell G Kluesner , Valentin Voillet, Vishaka Muhunthan, Fionnuala Morrish, James M Olson , Raphaël Gottado , Jay F Sarthy, Steven Henikoff , Lucas B Sullivan, Scott N Furlan, Stanley R Riddell

Journal: Immunity

PubMed ID: 38354704

Doi: 10.1016/j.immuni.2024.01.011

Products & Services: Codon Optimization

Local structural preferences in shaping tau amyloid polymorphism

Authors: Nikolaos Louros , Martin Wilkinson , Grigoria Tsaka , Meine Ramakers , Chiara Morelli , Teresa Garcia , Rodrigo Gallardo , Sam D'Haeyer , Vera Goossens , Dominique Audenaert , Dietmar Rudolf Thal , Ian R Mackenzie , Rosa Rademakers , Neil A Ranson , Sheena E Radford , Frederic Rousseau , Joost Schymkowitz

Journal: Nat Commun

PubMed ID: 38310108

Doi: 10.1038/s41467-024-45429-2

Products & Services: Peptide Synthesis

ZSCAN10 deficiency causes a neurodevelopmental disorder with characteristic oto-facial

Authors: Lucia Laugwitz, Fubo Cheng, Stephan C Collins, Alexander Hustinx, Nicolas Navarro, Simon Welsch, Helen Cox, Tzung-Chien Hsieh, Aswinkumar Vijayananth, Rebecca Buchert, Benjamin Bender, Stephanie Efthymiou, David Murphy, Faisal Zafar, Nuzhat Rana, Ute Grasshoff, Ruth J Falb, Mona Grimmel, Annette Seibt, Wenxu Zheng, Hamid Ghaedi, Marie Thirion, Sébastien Couette, Reza Azizimalamiri, Saeid Sadeghian, Hamid Galehdari, Mina Zamani, Jawaher Zeighami, Alireza Sedaghat, Samira Molaei Ramshe, Ali Zare, Behnam Alipoor, Dirk Klee,

Journal: Brain

PubMed ID: 38386308

Doi: 10.1093/brain/awae058

Products & Services: PCR Cloning and Subcloning

PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport

Authors: Paraskevi Tziortzouda , Jolien Steyaert , Wendy Scheveneels , Adria Sicart , Katarina Stoklund Dittlau , Adriana Margarida Barbosa Correia , Thibaut Burg , Arun Pal , Andreas Hermann , Philip Van Damme , Thomas G Moens , Ludo Van Den Bosch

Journal: Acta Neuropathol

PubMed ID: 38363426

Doi: 10.1007/s00401-024-02689-y

Products & Services: Peptide Synthesis

Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs

Authors: James Jiqi Wang, Sanshan Jin, Heng Zhang, Youwei Xu, Wen Hu, Yi Jiang, Chen Chen, Dao Wen Wang, H Eric Xu, Canrong Wu

Journal: Sci Adv .

PubMed ID: 38335293

Doi: 10.1126/sciadv.adk5184

Products & Services: Protein and Antibody Isolation

SRRM2 phase separation drives assembly of nuclear speckle subcompartments

Authors: Mengjun Zhang, Zhuang Gu, Shuanghui Guo, Yingtian Sun, Suibin Ma, Shuo Yang, Jierui Guo, Chenxi Fang, Li Shu, Yifan Ge, Zhongwen Chen, Bo Wang

Journal: Cell Rep .

PubMed ID: 38381607

Doi: 10.1016/j.celrep.2024.113827

Products & Services: Protein and Antibody Isolation

An Insertion Within SIRPβ1 Shows a Dual Effect Over Alzheimer’s Disease Cognitive Decline Altering the Microglial Response

Authors: José María García-Alberca, Itziar de Rojas, Elisabeth Sanchez-Mejias , Diego Garrido-Martín

Journal: JOURNAL OF ALZHEIMERS DISEASE

PubMed ID: 38427484

Doi: 10.3233/JAD-231150

Products & Services: Gene Synthesis

N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson's disease

Authors: Tao Guo, Lingyan Zhou, Min Xiong, Jing Xiong, Juan Huang, Yiming Li, Guoxin Zhang, Guiqin Chen, Zhi-Hao Wang, Tingting Xiao, Dan Hu, Anyu Bao, Zhentao Zhang

Journal: Aging Cell

PubMed ID: 38380563

Doi: 10.1111/acel.14124

Products & Services: Protein and Antibody Isolation

Cytokine responses to major human Cytomegalovirus antigens in mouse model

Authors: Sahar Essa, Hussain A Safar, Raj Raghupathy

Journal: Cytokine

PubMed ID: 38359558

Doi: 10.1016/j.cyto.2024.156546

Products & Services: Protein and Antibody Isolation