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A 14-amino acid cationic peptide Bolespleenin from the marine fish mudskipper Boleophthalmus pectinirostris exhibiting potent antimicrobial activity and therapeutic potential

Authors: Yuqi Bai, Weibin Zhang, Wenbin Zheng, Xin-Zhan Meng, Yingyi Duan, Chang Zhang, Fangyi Chen, Ke-Jian Wang

Journal: Biochem Pharmacol

PubMed ID: 38852647

Doi: 10.1016/j.bcp.2024.116344

Products & Services: Catalog Peptides

Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy

Authors: Vadim A Klenchin, Natasha M Clark, Nida K Keles, Saverio Capuano, Rosemarie Mason, Guangping Gao, Aimee Broman, Emek Kose, Taina T Immonen, Christine M Fennessey, Brandon F Keele, Jeffrey D Lifson, Mario Roederer, Matthew R Gardner, David T Evans

Journal: biorxiv

PubMed ID: 38895320

Doi: 10.1101/2024.05.30.593694

Products & Services: Codon Optimization

The role of MASP1 in the complement system and expression characteristics in response to GCRV infection in grass carp

Authors: Yuling Wei, Zhao Lv, Tiaoyi Xiao, Zongjun Du

Journal: Fish Shellfish Immunol

PubMed ID: 38901682

Doi: 10.1016/j.fsi.2024.109712

Products & Services: Protein and Antibody Isolation

Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein

Authors: Qi Yang, Bao Xue, Fengjiang Liu, Yongzhi Lu, Jielin Tang, Mengrong Yan, Qiong Wu, Ruyi Chen, Anqi Zhou, Lijie Liu, Junjun Liu, Changbin Qu, Qingxin Wu, Muqing Fu, Jiayi Zhong, Jianwei Dong, Sijie Chen, Fan Wang, Yuan Zhou, Jie Zheng, Wei Peng, Jinsai Shang, Xinwen Chen

Journal: Signal Transduct Target Ther

PubMed ID: 38853183

Doi: 10.1038/s41392-024-01858-5

Products & Services: Catalog Peptides

Exploring AlphaFold2 s Performance on Predicting Amino Acid Side-Chain Conformations and Its Utility in Crystal Structure Determination of B318L Protein

Authors: Haifan Zhao; Heng Zhang; Zhun She; Zengqiang Gao; Qi Wang; Zhi Geng; Yuhui Dong

Journal: International Journal of Molecular Sciences

PubMed ID: 36769074

Doi: 10.3390/ijms24032740

Exploring AlphaFold2 s Performance on Predicting Amino Acid Side-Chain Conformations and Its Utility in Crystal Structure Determination of B318L Protein

Authors: Haifan Zhao; Heng Zhang; Zhun She; Zengqiang Gao; Qi Wang; Zhi Geng; Yuhui Dong

Journal: International Journal of Molecular Sciences

PubMed ID: 36769074

Doi: 10.3390/ijms24032740

PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics

Authors: Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty

Journal: Nat Commun

PubMed ID: 38942756

Doi: 10.1038/s41467-024-49233-w

Products & Services: Gene Synthesis

Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity

Authors: Siddhi Omkar, Courtney Shrader, Joel R Hoskins, Jake T Kline, Megan M Mitchem, Luca Fornelli, Sue Wickner, Andrew W Truman

Journal: biorxiv

PubMed ID: 38915721

Doi: 10.1101/2024.06.13.598777

Products & Services: Molecular Biology Reagents

miR-520e and its promoter region DNA methylation as potential biomarkers in atherosclerosis

Authors: Mimi Mu, Gao Liu, Xiaoyu Ding, Lijun Xue, Dandan Li, Yunhua Zhu, Nan Zhang, Jia Wu, Junjun Wang

Journal: Biochem Cell Biol

PubMed ID: 38917487

Doi: 10.1139/bcb-2023-0326

Products & Services: Molecular Biology Reagents

Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels

Authors: Emily Mantlo, Jessie D Trujillo, Natasha N Gaudreault, Igor Morozov, Charles E Lewis, Franco Matias-Ferreyra, Chester McDowell, Dashzeveg Bold, Taeyong Kwon, Konner Cool, Velmurugan Balaraman, Daniel Madden, Bianca Artiaga, Jayme Souza-Neto, Jeffrey B Doty, Mariano Carossino, Udeni Balasuriya, William C Wilson, Nikolaus Osterrieder, Lisa Hensley, Juergen A Richt

Journal: Emerg Microbes Infect

PubMed ID: 38712637

Doi: 10.1080/22221751.2024.2352434

Products & Services: PCR Cloning and Subcloning