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Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation

Authors: Hongyi Zhou , Vijay Patel , Robert Rice , Richard Lee , Ha Won Kim , Neal L Weintraub , Huabo Su , Weiqin Chen

Journal: Cells

PubMed ID: 39404417

Doi: 10.3390/cells13191654

Products & Services: CRISPR Libraries

Molecular Modeling and In Vitro Functional Analysis of the RGS12 PDZ Domain Variant Associated with High-Penetrance Familial Bipolar Disorder

Authors: Percy S Agogo-Mawuli, Joseph Mendez, Emily A Oestreich, Dustin E Bosch, David P Siderovski

Journal: International Journal of Molecular Sciences

PubMed ID: 39518985

Doi: 10.3390/ijms252111431

Products & Services: Peptide Synthesis Bacterial Expression

Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations

Authors: Yoshita Srivastava , Olayinka Akinyemi , Tiana C Rohe , Elizabeth M Pritchett , Cameron D Baker , Akshara Sharma , Jermaine L Jenkins , David H Mathews , Joseph E Wedekind

Journal: Nucleic Acids Research

PubMed ID: 39413212

Doi: 10.1093/nar/gkae886

Products & Services: CRISPR KI Templates PCR Cloning and Subcloning Mutagenesis Services

Disrupting Intracellular Homeostasis by Copper-Based Nanoinducer with Multiple Enzyme-Mimicking Activities to Induce Disulfidptosis-Enhanced Pyroptosis for Tumor Immunotherapy

Authors: Xiao-Kang Jin , Shun-Kang Zhang , Shi-Man Zhang , Jun-Long Liang , Xiao Yan , Yan-Tong Lin , Ran Meng , Zi-Han Xu , Chuan-Jun Liu , Xian-Zheng Zhang

Journal: ADVANCED MATERIALS

PubMed ID: 39468892

Doi: 10.1002/adma.202410957

Products & Services: Recombinant Proteins

The TMEM63B Channel Facilitates Intestinal Motility and Enhances Proliferation of Intestinal Stem Cells

Authors: Jing-Jing Tu , Yan-Yu Zang , Yun Stone Shi ,and Xiao-Yu Teng

Journal: Cells

Doi: doi.org/10.3390/cells13211784

Products & Services: Molecular Biology Reagents

5′-tRNAGly(GCC) halves generated by IRE1α are linked to the ER stress response

Authors: Hanyong Jin , Ji-Hyun Yeom , Eunkyoung Shin , Yoonjie Ha , Haifeng Liu , Daeyoung Kim , Minju Joo , Yong-Hak Kim , Hak Kyun Kim , Minkyung Ryu, Hong-Man Kim , Jeongkyu Kim , Keun P Kim , Yoonsoo Hahn , Jeehyeon Bae , Kangseok Lee

Journal: Nature Communications

PubMed ID: 39468069

Doi: 10.1038/s41467-024-53624-4

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Zinc oxide nanoparticles with catalase-like nanozyme activity and near-infrared light response: A combination of effective photodynamic therapy, autophagy, ferroptosis, and antitumor immunity

Authors: Jingru Wang , Man Liu , Jingwen Wang , Zhuoyue Li , Zhenhan Feng , Meiqi Xu , Hui Wang , Hui Li , Zhantao Li , Jianming Yu , Junwei Liu , Qingchao Wei , Shuang Zhang , Xuan Zhang

Journal: Acta Pharm Sin B

PubMed ID: 39525585

Doi: 10.1016/j.apsb.2024.07.002

Products & Services: Recombinant Proteins

Acute GARP Depletion Disrupts Vesicle Transport, Leading to Severe Defects in Sorting, Secretion and O-Glycosylation

Authors: Amrita Khakurel , Irina Pokrovskaya , Vladimir V Lupashin

Journal: Traffic

PubMed ID: 39416116

Doi: 10.1111/tra.70003

Products & Services: Protein and Antibody Isolation Gene Synthesis

Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection

Authors: Gema María Esteban-Ortega, Margarita Díaz-Guerra

Journal: biorxiv

Doi: doi.org/10.1101/2024.10.29.620835

Products & Services: Peptide Synthesis Protein and Antibody Isolation

ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity

Authors: Andrew E Becker, Paweł Kochanowski, Pui-Kei Wu, Elżbieta Wątor, Wenjing Chen, Koushik Guchhait, Artur P Biela, Przemysław Grudnik, Jong-In Park

Journal: Cell Reports

PubMed ID: 39392755

Doi: 10.1016/j.celrep.2024.114831

Products & Services: Gene Synthesis