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enAsCas12a Enables CRISPR-Directed Evolution to Screen for Functional Drug Resistance Mutations in Sequences Inaccessible to SpCas9

Authors: Neggers JE, Jacquemyn M, Dierckx T, Kleinstiver BP, Thibaut HJ, Daelemans D

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

PubMed ID: 33002419

Doi: 10.1016/j.ymthe.2020.09.025

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A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis

Authors: Li Li, Alejandro P Ugalde, Colinda L G J Scheele, Sebastian M Dieter, Remco Nagel, Jin Ma, Abhijeet Pataskar, Gozde Korkmaz, Ran Elkon, Miao-Ping Chien, Li You, Pin-Rui Su, Onno B Bleijerveld, Maarten Altelaar, Lyubomir Momchev, Zohar Manber, Ruiqi Han, Pieter C van Breugel, Rui Lopes, Peter Ten Dijke, Jacco van Rheenen, Reuven Agami

Journal: Genome Biol

PubMed ID: 33514403

Doi: 10.1186/s13059-021-02272-8

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Mapping Genetic Interactions in Human Cancer Cells Using a One-Step tRNA-CRISPR System

Authors: Derek Yisen Zhang, Xiong Gui, Xiaolong Yang

Journal: Methods Mol Biol

PubMed ID: 34590276

Doi: 10.1007/978-1-0716-1740-3_9

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Functional Atlas of Primary miRNA Maturation by the Microprocessor

Authors: Rice GM, Shivashankar V, Ma EJ, Baryza JL, Nutiu R

Journal: Molecular Cell

PubMed ID: 33188727

Doi: 10.1016/j.molcel.2020.10.028

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Genetic factors associated with age-related macular degeneration: identification of a novel PRPH2 single nucleotide polymorphism associated with increased risk of the disease

Authors: Zofia Ulańczyk, Aleksandra Grabowicz, Katarzyna Mozolewska-Piotrowska, Krzysztof Safranow, Miłosz Piotr Kawa, Andrzej Pałucha, Mariusz Krawczyk, Piotr Sikora, Ewa Matczyńska, Bogusław Machaliński, Anna Machalińska

Journal: Acta Ophthalmol

PubMed ID: 33354892

Doi: 10.1111/aos.14721

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Liquid drop of DNA libraries reveals total genome information

Authors: Terekhov SS, Eliseev IE, Ovchinnikova LA, Kabilov MR, Prjibelski AD, Tupikin AE, Smirnov IV, Belogurov AA Jr, Severinov KV, Lomakin YA, Altman S, Gabibov AG

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 33087570

Doi: 10.1073/pnas.2017138117

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Early medieval genetic data from Ural region evaluated in the light of archaeological evidence of ancient Hungarians

Authors: Csáky V, Gerber D, Szeifert B, Egyed B, Stégmár B, Botalov SG, Grudochko IV, Matveeva NP, Zelenkov AS, Sleptsova AV, Goldina RD, Danich AV, Mende BG, Türk A, Szécsényi-Nagy A

Journal: Scientific REPORTS

PubMed ID: 33154399

Doi: 10.1038/s41598-020-75910-z

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Regulation of single-cell genome organization into TADs and chromatin nanodomains

Authors: Szabo Q, Donjon A, Jerković I, Papadopoulos GL, Cheutin T, Bonev B, Nora EP, Bruneau BG, Bantignies F, Cavalli G

Journal: Nature Genetics

PubMed ID: 33077913

Doi: 10.1038/s41588-020-00716-8

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Genomics of Human Fibrotic Diseases: Disordered Wound Healing Response

Authors: Rivka C Stone, Vivien Chen, Jamie Burgess, Sukhmani Pannu, Marjana Tomic-Canic

Journal: Int J Mol Sci

PubMed ID: 33202590

Doi: 10.3390/ijms21228590

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Low cost DNA data storage using photolithographic synthesis and advanced information reconstruction and error correction

Authors: Philipp L Antkowiak, Jory Lietard, Mohammad Zalbagi Darestani, Mark M Somoza, Wendelin J Stark, Reinhard Heckel, Robert N Grass

Journal: Nat Commun

PubMed ID: 33093494

Doi: 10.1038/s41467-020-19148-3

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