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BRD9 inhibition overcomes oncolytic virus therapy resistance in glioblastoma

Authors: Chen Guo, Zhilin Long, Peng Lin, Yinan Shen, Yiye Zhong, Jingjing Qian, Jichuan Yu, Weixi Zhao, Fuyi Liu, Yiling Ma, Jian Zheng, Jiayao Yang, Shuai Zhao, Xiaojuan Ran, Zhen Xia, Congying Wu, Yujia Cai, Chen Wang, Qi Xie

Journal: Cell Reports Medicine

PubMed ID: 40744020

Doi: 10.1016/j.xcrm.2025.102258

Products & Services: GenCrispr Cas9 Genome Editing

Machine Learning-Aided Identification of Fecal Extracellular Vesicle microRNA Signatures for Noninvasive Detection of Colorectal Cancer

Authors: Zhaowei Zhang, Xuyang Liu, Chuanyue Peng, Rui Du, Xiaoqin Hong, Jia Xu, Jiaming Chen, Xiaomin Li, Yujing Tang, Yuwei Li, Yang Liu, Chen Xu, Dingbin Liu

Journal: ACS Nano

PubMed ID: 40033785

Doi: 10.1021/acsnano.4c16698

Products & Services: Synthetic sgRNA and crRNA Service GenCrispr Cas9 Genome Editing

Expanding Cas12a Activity Control with an RNA G-Quadruplex at the 5′ end of CRISPR RNA

Authors: Wenjuan Huang, Jiaqi Wang, Cheng Wang, Yuanfang Liu, Wentao Li, Qiaozhen Chen, Junqiu Zhai, Zhenyang Xiang, Chaoxing Liu

Journal: Advanced Science

PubMed ID: 39721016

Doi: 10.1002/advs.202411305

Products & Services: GenCrispr Cas9 Genome Editing

Improvement of TaC9-ABE mediated correction of human SMN2 gene

Authors: Xiaohua Peng, Yue Chi, Jinling Wang, Shuangpeng Li, Yang Liu, Chengcheng Tang, Xiaoqing Zhou, Xuan Lu, Yue Gao, Liangxue Lai, Min Chen, Qingjian Zou

Journal: Biotechnol Bioeng

PubMed ID: 38923503

Doi: 10.1002/bit.28780

Products & Services: GenCrispr Cas9 Genome Editing

The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+-mediated signaling via retinoic acid regulation of Rcan2 and Kcnk5b

Authors: Xiaowen Jiang, Kun Zhao, Yi Sun, Xinyue Song, Chao Yi, Tianlong Xiong, Sen Wang, Yi Yu, Xiduo Chen, Run Liu, Xin Yan, Christopher L Antos

Journal: PLoS Biol

PubMed ID: 38527087

Doi: journal.pbio.3002565

Products & Services: GenCrispr Cas9 Genome Editing

The CRISPR effector Cam1 mediates membrane depolarization for phage defence

Authors: Christian F. Baca, You Yu, Jakob T. Rostøl, Puja Majumder, Dinshaw J. Patel & Luciano A. Marraffini

Journal: Nature

PubMed ID: 38200316

Doi: 10.1038/s41586-023-06902-y

Products & Services: GenCrispr Cas9 Genome Editing

Molecular basis of Spns2-facilitated sphingosine-1-phosphate transport

Authors: Bin Pang , Leiye Yu , Tong Li , Haizhan Jiao , Xiaomei Wu , Jinxin Wang , Ruiping He , Yurou Zhang , Juan Wang , Hongli Hu , Wei Dai , Li Chen , Ruobing Ren

Journal: Cell Res .

PubMed ID: 38123824

Doi: 10.1038/s41422-023-00908-x

Products & Services: GenCrispr Cas9 Genome Editing

High-Throughput and Efficient Intracellular Delivery Method via a Vibration-Assisted Nanoneedle/Microfluidic Composite System

Authors: Xuan Li , Yuan Ma , Yu Xue , Xuanhe Zhang , Linwen Lv , Qianghua Quan , Yiqing Chen , Guoxu Yu , Zhenwei Liang , Xinping Zhang , Ding Weng , Lei Chen , Kui Chen , Xin Han , Jiadao Wang

Journal: ACS Nano

PubMed ID: 36479877

Doi: 10.1021/acsnano.2c07852

Products & Services: GenCrispr Cas9 Genome Editing Synthetic sgRNA and crRNA Service

Transcriptomic and Phenotypic Analysis of CRISPR/Cas9-Mediated Knockout in Zebrafish

Authors: Qianqian Yan, Wenhao Li, Xiaoting Gong, Ruiqin Hu, Liangbiao Chen

Journal: Genes (Basel)

PubMed ID: 36011351

Doi: 10.3390/genes13081441

Products & Services: GenCrispr Cas9 Genome Editing

HGT is widespread in insects and contributes to male courtship in lepidopterans

Authors: Yang Li , Zhiguo Liu , Chao Liu , Zheyi Shi , Lan Pang , Chuzhen Chen , Yun Chen , Ronghui Pan , Wenwu Zhou , Xue-Xin Chen , Antonis Rokas , Jianhua Huang , Xing-Xing Shen

Journal: Cell

PubMed ID: 35853453

Doi: doi.org/10.1016/j.cell.2022.06.014

Products & Services: GenCrispr Cas9 Genome Editing

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