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Simultaneous enhancement of multiple functional properties using evolution-informed protein design
Authors: Benjamin Fram, Ian Truebridge, Yang Su, Adam J Riesselman, John B Ingraham, Alessandro Passera, Eve Napier, Nicole N Thadani, Samuel Lim, Kristen Roberts, Gurleen Kaur, Michael Stiffler, Debora S Marks, Christopher D Bahl, Amir R Khan, Chris Sander, Nicholas P Gauthier
Journal: biorxiv
PubMed ID: 37214973
Doi: 10.1101/2023.05.09.539914
Products & Services: Molecular Biology Reagents   
Massively parallel evaluation and computational prediction of the activities and specificities of 17 small Cas9s
Authors: Sang-Yeon Seo, Seonwoo Min, Sungtae Lee, Jung Hwa Seo, Jinman Park, Hui Kwon Kim, Myungjae Song, Dawoon Baek, Sung-Rae Cho, Hyongbum Henry Kim
Journal: Nat Methods
PubMed ID: 37188955
Doi: 10.1038/s41592-023-01875-2
Products & Services: Molecular Biology Reagents   
The effects of free Cys residues on the structure, activity, and tetrameric stability of mammalian uricase
Authors: Yong Guo, Jingjing Huo, Runchao Bai, Jingyuan Zhang, Jipeng Yao, Kaijie Ma, Zengtao Zhang, Haigang Li, Chun Zhang
Journal: Appl Microbiol Biotechnol
PubMed ID: 37256327
Doi: 10.1007/s00253-023-12597-y
Products & Services: Molecular Biology Reagents   
The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms
Authors: Duy Lan Huong Bui, Andrew Roach, Jingxian Li, Sumit J Bandekar, Elizabeth Orput, Ritika Raghavan, Demet Araç, Richard C Sando
Journal: Cell Rep
PubMed ID: 37224017
Doi: 10.1016/j.celrep.2023.112552
Products & Services: Molecular Biology Reagents   
Development and evaluation of an indirect ELISA using a multiepitope antigen for the diagnosis of intestinal schistosomiasis
Authors: Karine Ferreira Lopes, Mariana Lourenço Freire, Dayane Costa Souza Lima, Martin Johannes Enk, Edward Oliveira, Stefan Michael Geiger
Journal: Parasitology
PubMed ID: 37092694
Doi: 10.1017/S0031182023000409
Products & Services: Molecular Biology Reagents   
Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas
Authors: Nicole L Grant, Kristen Kelly, Pauline Maiello, Helena Abbott, Shelby O'Connor, Philana Ling Lin, Charles A Scanga, JoAnne L Flynn
Journal: MBio
PubMed ID: 37039646
Doi: 10.1128/mbio.00477-23
Products & Services: Molecular Biology Reagents   
Interspecies/Intergroup Complementation of Orthotospovirus Replication and Movement through Reverse Genetics Systems
Authors: Mingfeng Feng, Minglong Chen, Yulong Yuan, Qinhai Liu, Ruixiang Cheng, Tongqing Yang, Luyao Li, Rong Guo, Yongxin Dong, Jing Chen, Yawen Yang, Yuling Yan, Hongmin Cui, Dong Jing, Jinrui Kang, Shuxian Chen, Jia Li, Min Zhu, Changjun Huang, Zhongkai Zhang, Richard Kormelink, Xiaorong Tao
Journal: J Virol
PubMed ID: 37022194
Doi: 10.1128/jvi.01809-22
Products & Services: Molecular Biology Reagents   
Protein Delivery to Insect Epithelial Cells In Vivo: Potential Application to Functional Molecular Analysis of Proteins in Butterfly Wing Development
Authors: Yugo Nakazato, Joji M Otaki
Journal: BioTech (Basel)
PubMed ID: 37092472
Doi: 10.3390/biotech12020028
Products & Services: Molecular Biology Reagents   
Is Penguin Circovirus Circulating Only in the Antarctic Circle? Lack of Viral Detection in Namibia
Authors: Laura C Roberts, Umberto Molini, Lauren M Coetzee, Siegfried Khaiseb, Jean-Paul Roux, Jessica Kemper, David G Roberts, Katrin Ludynia, Marcus Doherr, Darrell Abernethy, Giovanni Franzo
Journal: Animals (Basel)
PubMed ID: 37174486
Doi: 10.3390/ani13091449
Products & Services: Molecular Biology Reagents   
ATG8-dependent LMX1B-autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience
Authors: Natalia Jiménez-Moreno, Madhu Kollareddy, Petros Stathakos, Joanna J Moss, Zuriñe Antón, Deborah K Shoemark, Richard B Sessions, Ralph Witzgall, Maeve Caldwell, Jon D Lane
Journal: J Cell Biol
PubMed ID: 37014324
Doi: 10.1083/jcb.201910133
Products & Services: Molecular Biology Reagents   
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