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Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis

Authors: Stephanie M Bozonet, Nicholas J Magon, Abigail J Schwartfeger, Andreas Konigstorfer, Sarah G Heath, Margreet C M Vissers, Vanessa K Morris, Christoph Göbl, James M Murphy, Guy S Salvesen, Mark B Hampton

Journal: J Biol Chem

PubMed ID: 37150321

Doi: 10.1016/j.jbc.2023.104792

Products & Services: Molecular Biology Reagents

Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction

Authors: Joka Pipercevic, Bastian Kohl, Ruta Gerasimaite, Véronique Comte-Miserez, Sarah Hostachy, Thomas Müntener, Elia Agustoni, Henning Jacob Jessen, Dorothea Fiedler, Andreas Mayer, Sebastian Hiller

Journal: Nat Commun

PubMed ID: 37156835

Doi: 10.1038/s41467-023-38315-w

Products & Services: Molecular Biology Reagents

Leptospiral imelysin (LIC_10713) is secretory, immunogenic and binds to laminin, fibronectin, and collagen IV

Authors: Abhijit Sarma, Dhandapani Gunasekaran, Homen Phukan, Akhil Baby, Suneetha Hariharan, Arun Kumar De, Debasis Bhattacharya, Sankar Natesan, Jebasingh Tennyson, Madathiparambil Gopalakrishnan Madanan

Journal: Appl Microbiol Biotechnol

PubMed ID: 37227474

Doi: 10.1007/s00253-023-12573-6

Products & Services: Molecular Biology Reagents

CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation

Authors: Min Qiu, Zhinang Yin, Honghong Wang, Lingyu Lei, Conghui Li, Yali Cui, Rong Dai, Peiyuan Yang, Ying Xiang, Qiuzi Li, Junhui Lv, Zhuang Hu, Min Chen, Hai-Bing Zhou, Pingping Fang, Ruijing Xiao, Kaiwei Liang

Journal: Sci Adv

PubMed ID: 37205756

Doi: 10.1126/sciadv.adf8698

Products & Services: Molecular Biology Reagents

Analysis and comparisons of gene expression changes in patient- derived neurons from ROHHAD, CCHS, and PWS

Authors: A Kaitlyn Victor, Tayler Hedgecock, Martin Donaldson, Daniel Johnson, Casey M Rand, Debra E Weese-Mayer, Lawrence T Reiter

Journal: Front Pediatr

PubMed ID: 37234859

Doi: 10.3389/fped.2023.1090084

Products & Services: Molecular Biology Reagents

Antibacterial mechanism of the novel antimicrobial peptide Jelleine-Ic and its efficacy in controlling Pseudomonas syringae pv actinidiae in kiwifruit

Authors: Mingyu Zhang, Lifang Wang, Wei Tang, Yue Xing, Pu Liu, Xiangli Dang

Journal: Pest Manag Sci

PubMed ID: 37184207

Doi: 10.1002/ps.7548

Products & Services: Molecular Biology Reagents

Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid

Authors: Hai-Fan Zhao, Liang Meng, Zhi Geng, Zeng-Qiang Gao, Yu-Hui Dong, Hai-Wei Wang, Heng Zhang

Journal: PLoS Pathog

PubMed ID: 37253057

Doi: 10.1371/journal.ppat.1011411

Products & Services: Molecular Biology Reagents

Immunological comparison of recombinant shrimp allergen Pen m 4, produced in Pichia pastoris and Escherichia coli

Authors: Juta Rainyte, Gintautas Zvirblis, Mindaugas Zaveckas, Indre Kucinskaite-Kodze, Laimis Silimavicius, Rasa Petraityte-Burneikiene

Journal: J Biotechnol

PubMed ID: 37164269

Doi: 10.1016/j.jbiotec.2023.05.002

Products & Services: Molecular Biology Reagents

Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies

Authors: Wei Shi, Yin Wang, Yuehui Zhao, Justin Jimin Kim, Haoyan Li, Chenling Meng, Feiyu Chen, Jie Zhang, Duncan H Mak, Vivien Van, Javier Leo, Brad St Croix, Ana Aparicio, Di Zhao

Journal: Sci Transl Med

PubMed ID: 37163614

Doi: 10.1126/scitranslmed.adf6724

Products & Services: Molecular Biology Reagents

Encapsulated Allografts Preclude Host Sensitization and Promote Ovarian Endocrine Function in Ovariectomized Young Rhesus Monkeys and Sensitized Mice

Authors: James R Day, Colleen L Flanagan, Anu David, Dennis J Hartigan-O'Connor, Mayara Garcia de Mattos Barbosa, Michele L Martinez, Charles Lee, Jenna Barnes, Evan Farkash, Mary Zelinski, Alice Tarantal, Marilia Cascalho, Ariella Shikanov

Journal: Bioengineering (Basel)

PubMed ID: 37237620

Doi: 10.3390/bioengineering10050550

Products & Services: Molecular Biology Reagents