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A new trivalent recombinant protein for type 2 diabetes mellitus with oral delivery potential: design, expression, and experimental validation

Authors: Maryam Ehsasatvatan, Bahram Baghban Kohnehrouz

Journal: J Biomol Struct Dyn

PubMed ID: 38468545

Doi: 10.1080/07391102.2024.2329290

Products & Services: Molecular Biology Reagents

Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antivirals

Authors: Jimena Pérez-Vargas, Gabriel Lemieux, Connor A H Thompson, Antoine Désilets, Siobhan Ennis, Guang Gao, Danielle G Gordon, Annika Lea Schulz, Masahiro Niikura, Ivan Robert Nabi, Mel Krajden, Pierre-Luc Boudreault, Richard Leduc, François Jean

Journal: Antiviral Res

PubMed ID: 38548023

Doi: 10.1016/j.antiviral.2024.105869

Products & Services: Molecular Biology Reagents

HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species

Authors: Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel

Journal: Nat Commun

PubMed ID: 38499535

Doi: 10.1038/s41467-024-46538-8

Products & Services: Molecular Biology Reagents

Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography

Authors: Kaylen R Meeks, Juan Ji , Mykola V Protopopov , Olga O Tarkhanova , Yurii S Moroz , John J Tanner

Journal: J Chem Inf Model

PubMed ID: 38411104

Doi: 10.1021/acs.jcim.3c01879

Products & Services: Molecular Biology Reagents

Exploring functional genes' correlation with ()-equol concentration and new daidzein racemase identification

Authors: Yun-Fei Hu, Shu Luo, Sheng-Qi Wang, Ke-Xin Chen, Wei-Xuan Zhong, Bai-Yuan Li, Lin-Yan Cao, Hua-Hai Chen, Ye-Shi Yin

Journal: Appl Environ Microbiol

PubMed ID: 38501861

Doi: 10.1128/aem.00007-24

Products & Services: Molecular Biology Reagents

mmu-miR-374b-5p modulated inflammatory factors via downregulation of C/EBP β/NF-κB signaling in Kupffer cells during Echinococcus multilocularis infection

Authors: Guiting Pu, Yanping Li, Tingli Liu, Hong Li, Liqun Wang, Guoliang Chen, Shanling Cao, Hong Yin, Tharheer Oluwashola Amuda, Xiaola Guo, Xuenong Luo

Journal: Parasit Vectors

PubMed ID: 38553755

Doi: 10.1186/s13071-024-06238-0

Products & Services: Molecular Biology Reagents

Modulation of Primary and Secondary Processes in Tau Fibril Formation by Salt-Induced Dynamics

Authors: Arshad Abdul Vahid, Muhammed Shafeek Oliyantakath Hassan, Allwin Ebenezer Sahayaraj, Ann Teres Babu, Safwa T Kizhakkeduth, Vinesh Vijayan

Journal: ACS Chem Neurosci

PubMed ID: 38433380

Doi: 10.1021/acschemneuro.3c00852

Products & Services: Molecular Biology Reagents

Nanopore analysis of cis-diols in fruits

Authors: Pingping Fan, Zhenyuan Cao, Shanyu Zhang, Yuqin Wang, Yunqi Xiao, Wendong Jia, Panke Zhang, Shuo Huang

Journal: Nat Commun

PubMed ID: 38443434

Doi: 10.1038/s41467-024-46303-x

Products & Services: Molecular Biology Reagents

Knockout and Replacement Gene Surgery to Treat Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa

Authors: Xuehan Sun, Chen Liang, Yangcan Chen, Tongtong Cui, Jiabao Han, Moyu Dai, Ying Zhang, Qi Zhou, Wei Li

Journal: Hum Gene Ther

PubMed ID: 38368562

Doi: 10.1089/hum.2023.201

Products & Services: Molecular Biology Reagents

Construction of recombinant pseudorabies virus expressing PCV2 Cap, PCV3 Cap, and IL-4: investigation of their biological characteristics and immunogenicity

Authors: Yanting Yang, Zhiwen Xu, Qian Tao, Lei Xu, Sirui Gu, Yao Huang, Zheyan Liu, Yang Zhang, Jianhua Wen, Siyuan Lai, Ling Zhu

Journal: Front Immunol

PubMed ID: 38571947

Doi: 10.3389/fimmu.2024.1339387

Products & Services: Molecular Biology Reagents