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Harnessing type I CRISPR-Cas systems for genome engineering in human cells

Authors: Cameron P1, Coons MM2, Klompe SE2,3, Lied AM2, Smith SC2, Vidal B2, Donohoue PD2, Rotstein T2,4, Kohrs BW2, Nyer DB2, Kennedy R2,5, Banh LM2, Williams C2, Toh MS2, Irby MJ2, Edwards LS2, Lin CH2, Owen ALG2, Künne T6, van der Oost J6, Brouns SJJ6,7, Slorach EM2, Fuller CK2, Gradia S2, Kanner SB2, May AP2,8, Sternberg SH9,10.

Journal: Nat Biotechnol.

PubMed ID: 31740839

Products & Services: Molecular Biology Reagents

A Central Region of NF-κB Essential Modulator Is Required for IKKβ-Induced Conformational Change and for Signal Propagation.

Authors: ShafferRobert，DeMariaAnthony M，KagermazovaLarisa，LiuYuekun，BabaeiMilad，Caban-PenixSuhaily，CervantesArisdelsy，JehleStefan，MakowskiLee，GilmoreThomas D，WhittyAdrian，AllenKar

Journal: Biochemistry

PubMed ID: 31145594

Doi: 10.1021/acs.biochem.8b01316

Products & Services: Molecular Biology Reagents

Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth Halophile .

Authors: OskoJeremy D，RooseBenjamin W，ShinskyStephen A，ChristiansonDav

Journal: Biochemistry

PubMed ID: 31436969

Doi: 10.1021/acs.biochem.9b00582

Products & Services: Molecular Biology Reagents

The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern

Authors: Saman Amini, Annika Jacobsen, Olga Ivanova, Philip Lijnzaad, Jaap Heringa, Frank C P Holstege, K Anton Feenstra, Patrick Kemmeren

Journal: PLoS Comput Biol

PubMed ID: 31083661

Doi: 10.1371/journal.pcbi.1007061

Products & Services: Molecular Biology Reagents

Molecular Dynamics model of peptide-protein conjugation: case study of covalent complex between Sos1 peptide and N-terminal SH3 domain from Grb2

Authors: Luzik DA, Rogacheva ON, Izmailov SA, Indeykina MI, Kononikhin AS, Skrynnikov NR,

Journal: Sci Rep

PubMed ID: 31882608

Doi: 10.1038/s41598-019-56078-7

Products & Services: Molecular Biology Reagents

Cutaneous microenvironment responsive microneedle patch for rapid gene release to treat subdermal tumor.

Authors: Li X, Xu Q, Zhang P, Zhao X, Wang Y.

Journal: J Control Release

PubMed ID: 31629710

Products & Services: Molecular Biology Reagents

BRCA1-associated protein inhibits glioma cell proliferation and migration and glioma stem cell self-renewal via the TGF-β/PI3K/AKT/mTOR signalling pathway.

Authors: Wang B,, Cao C, Liu X, He X, Zhuang H, Wang D, Chen B.

Journal: Cell Oncol (Dordr)

PubMed ID: 31776938

Products & Services: Molecular Biology Reagents

Development and Evaluation of a Duo Chikungunya Virus Real-Time RT-PCR Assay Targeting Two Regions within the Genome.

Authors: Thirion L, Pezzi L,, Corcostegui I, Dubot-Pérès A, Falchi A, de Lamballerie X, Charrel RN,.

Journal: Viruses

PubMed ID: 31443243

Doi: 10.3390/v11080755

Products & Services: Molecular Biology Reagents

Biodegradation of dicofol by Microbacterium sp D-2 isolated from pesticide-contaminated agricultural soil

Authors: Peng Lu, Hong-ming Liu & Ai-min Liu

Journal: springeropen

Doi: 10.1186/s13765-019-0480-y

Products & Services: Molecular Biology Reagents

Site-Specific Modification of Proteins via Trypsiligase

Authors: Liebscher S, Bordusa F.

Journal: Methods Mol Biol

PubMed ID: 31332750

Doi: 10.1007/978-1-4939-9654-4_8

Products & Services: Molecular Biology Reagents