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页码: 125/163 每页显示数量

Harnessing type I CRISPR-Cas systems for genome engineering in human cells

Authors: Cameron P1, Coons MM2, Klompe SE2,3, Lied AM2, Smith SC2, Vidal B2, Donohoue PD2, Rotstein T2,4, Kohrs BW2, Nyer DB2, Kennedy R2,5, Banh LM2, Williams C2, Toh MS2, Irby MJ2, Edwards LS2, Lin CH2, Owen ALG2, Künne T6, van der Oost J6, Brouns SJJ6,7, Slorach EM2, Fuller CK2, Gradia S2, Kanner SB2, May AP2,8, Sternberg SH9,10.

Journal: Nat Biotechnol.

PubMed ID: 31740839

Products & Services: Molecular Biology Reagents

Dopamine Receptor D3 Expression Is Altered in CD4+ T-Cells From Parkinson's Disease Patients and Its Pharmacologic Inhibition Attenuates the Motor Impairment in a Mouse Model

Authors: Elgueta D, Contreras F, Prado C, Montoya A, Ugalde V, Chovar O, Villagra R, Henríquez C, Abellanas MA, Aymerich MS, Franco R, Pacheco R, .

Journal: Front Immunol

PubMed ID: 31118938

Doi: 10.3389/fimmu.2019.00981

Products & Services: Molecular Biology Reagents

SpyTag-SpyCatcher Chemistry for Protein Bioconjugation In Vitro and Protein Topology Engineering In Vivo

Authors: Wang XW, Zhang WB.

Journal: Methods Mol Biol

PubMed ID: 31332761

Doi: 10.1007/978-1-4939-9654-4_19

Products & Services: Molecular Biology Reagents

Optogenetic Control of Programmable Genome Editing by Photoactivatable CRISPR/Cas9 Nanosystem in the Second Near-Infrared Window

Authors: Xiaohong Chen, Yuxuan Chen, Huhu Xin, Tao Wan, Yuan Ping

Journal: biorxiv

Doi: 10.1101/673715

Products & Services: Molecular Biology Reagents

DUX4 regulates oocyte to embryo transition in human

Authors: Sanna Vuoristo, Christel Hydén-Granskog, Masahito Yoshihara, Lisa Gawriyski, Anastassius Damdimopoulos, Shruti Bhagat, Kosuke Hashimoto, Kaarel Krjutškov, Sini Ezer, Priit Paluoja, Karolina Lundin, Pauliina Paloviita, Gaëlle Recher, Vipin Ranga, Tomi Airenne, Mahlet Tamirat, Eeva-Mari Jouhilahti, Timo Otonkoski, Juha S. Tapanainen, Hideya Kawaji, Yasuhiro Murakawa, Thomas R. Bürglin, Markku Varjosalo, Mark S. Johnson, Timo Tuuri, Shintaro Katayama, Juha Kere

Journal: biorxiv

Doi: 10.1101/732289

Products & Services: Molecular Biology Reagents

The Cryo-EM Structure of a Pannexin 1 Channel Reveals an Extracellular Gating Mechanism

Authors: Kevin Michalski, Johanna L. Syrjanen, Erik Henze, Julia Kumpf, Hiro Furukawa, Toshimitsu Kawate

Journal: biorxiv

Doi: 10.1101/2019.12.30.890780

Products & Services: Molecular Biology Reagents

The Ca-loop in thymidylate kinase is critical for growth and contributes to pyrimidine drug sensitivity of .

Authors: HuangChang-Yu，ChenYee-Chun，Wu-HsiehBetty A，FangJim-Min，ChangZee

Journal: J. Biol. Chem.

PubMed ID: 31152062

Doi: 10.1074/jbc.RA118.006798

Products & Services: Molecular Biology Reagents

Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84.

Authors: MontgomeryMagdalene K，OsborneBrenna，BrandonAmanda E，O'ReillyLiam，FiveashCorrine E，BrownSimon H J，WilkinsBrendan P，SamsudeenAzrah，YuJosephine，DevanapalliBeena，HertzogAshley，TolunAdviye A，KavanaghTomas，CooperAntony A，MitchellTodd W，BidenTrevor J，SmithNicola J，CooneyGregory J，TurnerN

Journal: FASEB J.

PubMed ID: 31415180

Doi: 10.1096/fj.201900234R

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DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region.

Authors: CuppariAnna，Fernández-MillánPablo，BattistiniFederica，Tarrés-SoléAleix，LyonnaisSébastien，IruelaGuillermo，Ruiz-LópezElena，EncisoYuliana，Rubio-CosialsAnna，ProhensRafel，PonsMiquel，AlfonsoCarlos，TóthKatalin，RivasGermán，OrozcoModesto，SolàM

Journal: Nucleic Acids Res.

PubMed ID: 31114891

Doi: 10.1093/nar/gkz406

Products & Services: Molecular Biology Reagents

The Biosynthesis of Flavin Cofactors in Listeria monocytogenes.

Authors: SebastiánMaria，Arilla-LunaSonia，BellalouJacques，YruelaInmaculada，MedinaMila

Journal: J. Mol. Biol.

PubMed ID: 31132361

Doi: 10.1016/j.jmb.2019.05.029

Products & Services: Molecular Biology Reagents