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Exosomes derived from miR-155-5p-overexpressing synovial mesenchymal stem cells prevent osteoarthritis via enhancing proliferation and migration, attenuating apoptosis, and modulating extracellular matrix secretion in chondrocytes

Authors: Zhirong Wang, Kai Yan, Gaoran Ge, Di Zhang, Jiaxiang Bai, Xiaobin Guo, Jing Zhou, Tianpeng Xu, Menglei Xu, Xiao Long, Yuefeng Hao, Dechun Geng

Journal: Cell Biol Toxicol

PubMed ID: 33099657

Doi: 10.1007/s10565-020-09559-9

Products & Services: Molecular Biology Reagents

BBS4 Is Essential for Nuclear Transport of Transcription Factors Mediating Neuronal ER Stress Response

Authors: Avital Horwitz, Ruth Birk

Journal: Mol Neurobiol

PubMed ID: 32894499

Doi: 10.1007/s12035-020-02104-z

Products & Services: Molecular Biology Reagents

A high-throughput assay for the quantification of intact Insulin-like Growth Factor I in human serum using online SPE-LC-HRMS

Authors: Gilles Coppieters, Péter Judák, Nicolas Van Haecke, Pieter Van Renterghem, Peter Van Eenoo, Koen Deventer

Journal: Clin Chim Acta

PubMed ID: 32739215

Doi: 10.1016/j.cca.2020.07.054

Products & Services: Molecular Biology Reagents

Human islets contain a subpopulation of glucagon-like peptide-1 secreting α cells that is increased in type 2 diabetes

Authors: Scott A Campbell, Dominic P Golec, Matt Hubert, Janyne Johnson, Nicole Salamon, Amy Barr, Patrick E MacDonald, Koenraad Philippaert, Peter E Light

Journal: Mol Metab

PubMed ID: 32413586

Doi: 10.1016/j.molmet.2020.101014

Products & Services: Molecular Biology Reagents

Defects in G-Actin Incorporation into Filaments in Myoblasts Derived from Dysferlinopathy Patients Are Restored by Dysferlin C2 Domains

Authors: Báez-Matus X, Figueroa-Cares C, Gónzalez-Jamett AM, Almarza-Salazar H, Arriagada C, Maldifassi MC, Guerra MJ, Mouly V, Bigot A, Caviedes P, Cárdenas AM

Journal: International Journal of Molecular Sciences

PubMed ID: 31861684

Doi: 10.3390/ijms21010037

Products & Services: Molecular Biology Reagents

Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase

Authors: Lazo JS, Blanco IK, Tasker NR, Rastelli EJ, Burnett JC, Garrott SR, Hart DJ, McCloud RL, Hsu KL, Wipf P, Sharlow ER

Journal: The Journal of pharmacology and experimental therapeutics

PubMed ID: 31601683

Doi: 10.1124/jpet.119.262188

Products & Services: Molecular Biology Reagents

Effectiveness of six molecular typing methods as epidemiological tools for the study of isolates in two Colombian regions

Authors: Kelly Lozano-Villegas, Roy Rodríguez-Hernández, Iang Rondón-Barragán

Journal: Vet World

PubMed ID: 32095053

Doi: 10.14202/vetworld.2019.1998-2006

Products & Services: Molecular Biology Reagents

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates

Authors: Elfarrash S, Jensen NM, Ferreira N, Betzer C, Thevathasan JV, Diekmann R, Adel M, Omar NM, Boraie MZ, Gad S, Ries J, Kirik D, Nabavi S, Jensen PH

Journal: Acta neuropathologica communications

PubMed ID: 31856920

Doi: 10.1186/s40478-019-0865-5

Products & Services: Molecular Biology Reagents

Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α_2C Adrenergic Receptor

Authors: Chen X, Xu Y, Qu L, Wu L, Han GW, Guo Y, Wu Y, Zhou Q, Sun Q, Chu C, Yang J, Yang L, Wang Q, Yuan S, Wang L, Hu T, Tao H, Sun Y, Song Y, Hu L, Liu ZJ, Stevens RC, Zhao S, Wu D, Zhong G

Journal: Cell Reports

PubMed ID: 31801061

Doi: 10.1016/j.celrep.2019.10.112

Products & Services: Molecular Biology Reagents

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM

Authors: Dutka P, Mukherjee S, Gao X, Kang Y, de Waal PW, Wang L, Zhuang Y, Melcher K, Zhang C, Xu HE, Kossiakoff AA

Journal: Structure (London, England : 1993)

PubMed ID: 31669042

Doi: 10.1016/j.str.2019.10.004

Products & Services: Molecular Biology Reagents