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Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with host factor FMRP in the murine brain
Authors: Xuxiao Zhang, Juan Pu, Yipeng Sun, Bi Yuhai, Zhimin Jiang, Guanlong Xu, Hongyu Zhang, Jing Cao, Kin-Chow Chang, Jinhua Liu, Honglei Sun
Journal: J Virol
PubMed ID: 33408179
Doi: 10.1128/JVI.01272-20
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Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism
Authors: Mattia Deluigi, Alexander Klipp, Christoph Klenk, Lisa Merklinger, Stefanie A Eberle, Lena Morstein, Philipp Heine, Peer R E Mittl, Patrick Ernst, Theodore M Kamenecka, Yuanjun He, Santiago Vacca, Pascal Egloff, Annemarie Honegger, Andreas Plückthun
Journal: Sci Adv
PubMed ID: 33571132
Doi: 10.1126/sciadv.abe5504
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Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair
Authors: Natasha C Koussa, Duncan J Smith
Journal: PLoS Genet
PubMed ID: 33493195
Doi: 10.1371/journal.pgen.1009322
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Physiological Characteristics of Strains and Their Alleviation Effects against Inflammatory Bowel Disease
Authors: Yang Liu, Yifeng Li, Xinjie Yu, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Qixiao Zhai, Wei Chen
Journal: J Microbiol Biotechnol
PubMed ID: 32522964
Doi: 10.4014/jmb.2003.03041
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A novel and sensitive real-time PCR system for universal detection of poxviruses
Authors: Léa Luciani, Lucia Inchauste, Olivier Ferraris, Rémi Charrel, Antoine Nougairède, Géraldine Piorkowski, Christophe Peyrefitte, Stéphane Bertagnoli, Xavier de Lamballerie, Stéphane Priet
Journal: Sci Rep
PubMed ID: 33469067
Doi: 10.1038/s41598-021-81376-4
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Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3
Authors: Anderson SE, Longbotham JE, O'Kane PT, Ugur FS, Fujimori DG, Mrksich M
Journal: ACS Chemical Biology
PubMed ID: 33314922
Doi: 10.1021/acschembio.0c00891
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Competition of Ligands and the 18-mer Binding Domain of the RHAU Helicase for G-Quadruplexes: Orthosteric or Allosteric Binding Mechanism?
Authors: Marchand A, Beauvineau C, Teulade-Fichou MP, Zenobi R
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
PubMed ID: 33617136
Doi: 10.1002/chem.202004040
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Lobaplatin Enhances Radioactive I Seed-Induced Apoptosis and Anti-Proliferative Effect in Non-Small Cell Lung Cancer by Suppressing the AKT/mTOR Pathway
Authors: Jia-Hui Rong, Dong Li, Yu-Liang Li
Journal: Onco Targets Ther
PubMed ID: 33469307
Doi: 10.2147/OTT.S288012
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Cardiac Troponin I R193H Mutation Is Associated with Mitochondrial Damage in Cardiomyocytes
Authors: Jing Luo, Weian Zhao, Yi Gan, Bo Pan, Lingjuan Liu, Zhenguo Liu, Jie Tian
Journal: DNA Cell Biol
PubMed ID: 33465007
Doi: 10.1089/dna.2020.5828
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CREB Participates in Paclitaxel-Induced Neuropathic Pain Genesis Through Transcriptional Activation of Dnmt3a in Primary Sensory Neurons
Authors: Yang Y, Wen J, Zheng B, Wu S, Mao Q, Liang L, Li Z, Bachmann T, Bekker A, Tao YX
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
PubMed ID: 33051852
Doi: 10.1007/s13311-020-00931-5
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