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Porcine circovirus type 2 infection attenuates the K63-linked ubiquitination of STING to inhibit IFN-β induction via p38-MAPK pathway

Authors: Xingchen Wu, Zhenyu Wang, Dan Qiao, Yu Yuan, Cong Han, Nan Yang, Ruizhen Li, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 33984793

Doi: 10.1016/j.vetmic.2021.109098

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The aminosterol Claramine inhibits β-secretase 1-mediated insulin receptor cleavage

Authors: Bénédicte Gaborit, Roland Govers, Alexandre Altié, Jean Michel Brunel, Pierre Morange, Franck Peiretti

Journal: J Biol Chem

PubMed ID: 34029592

Doi: 10.1016/j.jbc.2021.100818

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Selective and noncovalent targeting of RAS mutants for inhibition and degradation

Authors: Kai Wen Teng, Steven T Tsai, Takamitsu Hattori, Carmine Fedele, Akiko Koide, Chao Yang, Xuben Hou, Yingkai Zhang, Benjamin G Neel, John P O'Bryan, Shohei Koide

Journal: Nat Commun

PubMed ID: 33976200

Doi: 10.1038/s41467-021-22969-5

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In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activity

Authors: Lyndsay R Watkins, Cesare Orlandi

Journal: Br J Pharmacol

PubMed ID: 33784795

Doi: 10.1111/bph.15468

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Rituximab and Canakinumab Use During Lactation: No Detectable Serum Levels in Breastfed Infants

Authors: Nicole Bosshard, Astrid Zbinden, Klara Kristin Eriksson, Frauke Förger

Journal: Rheumatol Ther

PubMed ID: 33999372

Doi: 10.1007/s40744-021-00313-z

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Neither gonadotropin nor cumulus cell expansion is needed for the maturation of competent porcine oocytes in vitro

Authors: Bethany K Redel, Lee D Spate, Ye Yuan, Clifton N Murphy, R Michael Roberts, Randall S Prather

Journal: Biol Reprod

PubMed ID: 33962465

Doi: 10.1093/biolre/ioab090

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Mitohormesis reprogrammes macrophage metabolism to enforce tolerance

Authors: Greg A Timblin, Kevin M Tharp, Breanna Ford, Janet M Winchester, Jerome Wang, Stella Zhu, Rida I Khan, Shannon K Louie, Anthony T Iavarone, Johanna Ten Hoeve, Daniel K Nomura, Andreas Stahl, Kaoru Saijo

Journal: Nat Metab

PubMed ID: 34031590

Doi: 10.1038/s42255-021-00392-w

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Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway

Authors: Yen-Chen Lin, Meenakshi Sundaram Kumar, Nandini Ramesh, Eric N Anderson, Aivi T Nguyen, Boram Kim, Simon Cheung, Justin A McDonough, William C Skarnes, Rodrigo Lopez-Gonzalez, John E Landers, Nicolas L Fawzi, Ian R A Mackenzie, Edward B Lee, Jeffrey A Nickerson, David Grunwald, Udai B Pandey, Daryl A Bosco

Journal: Nat Neurosci

PubMed ID: 34059832

Doi: 10.1038/s41593-021-00859-9

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Integrating quantitative proteomics with accurate genome profiling of transcription factors by greenCUT&RUN

Authors: Sheikh Nizamuddin, Stefanie Koidl, Tanja Bhuiyan, Tamara V Werner, Martin L Biniossek, Alexandre M J J Bonvin, Silke Lassmann, HThMarc Timmers

Journal: Nucleic Acids Res

PubMed ID: 33524153

Doi: 10.1093/nar/gkab038

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Mechanical ventilation enhances Acinetobacter baumannii-induced lung injury through JNK pathways

Authors: Tzyy-Bin Tsay, Wan-Hsuan Chang, Ching-Mei Hsu, Lee-Wei Chen

Journal: Respir Res

PubMed ID: 34022899

Doi: 10.1186/s12931-021-01739-3

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