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Recombinant adenovirus expressing the fusion protein PD1PVR improves CD8 T cell-mediated antitumor efficacy with long-term tumor-specific immune surveillance in hepatocellular carcinoma

Authors: Hailin Zhang, Yonghui Zhang, Jie Dong, Shuguang Zuo, Gang Meng, Junhua Wu, Jiwu Wei

Journal: Cell Oncol (Dordr)

PubMed ID: 34491549

Doi: 10.1007/s13402-021-00633-w

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DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation

Authors: Hung-Hsi Chen, Hsin-I Yu, Rudy Rudy, Sim-Lin Lim, Yi-Fen Chen, Shu-Hsing Wu, Shu-Chun Lin, Muh-Hwa Yang, Woan-Yuh Tarn

Journal: iScience

PubMed ID: 34568799

Doi: 10.1016/j.isci.2021.103086

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A bioluminescent and homogeneous SARS-CoV-2 spike RBD and hACE2 interaction assay for antiviral screening and monitoring patient neutralizing antibody levels

Authors: Juliano Alves, Laurie Engel, Renata de Vasconcelos Cabral, Eduardo L Rodrigues, Liane de Jesus Ribeiro, Luiza M Higa, Orlando da Costa Ferreira Júnior, Terezinha Marta P P Castiñeiras, Isabela de Carvalho Leitão, Amilcar Tanuri, Said A Goueli, Hicham Zegzouti

Journal: Sci Rep

PubMed ID: 34531417

Doi: 10.1038/s41598-021-97330-3

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Insights into the dual functions of AcrIF14 during the inhibition of type I-F CRISPR-Cas surveillance complex

Authors: Xi Liu, Laixing Zhang, Yu Xiu, Teng Gao, Ling Huang, Yongchao Xie, Lingguang Yang, Wenhe Wang, Peiyi Wang, Yi Zhang, Maojun Yang, Yue Feng

Journal: Nucleic Acids Res

PubMed ID: 34432044

Doi: 10.1093/nar/gkab738

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Isotype-Specific Fc Effector Functions Enhance Antibody-Mediated Rift Valley Fever Virus Protection

Authors: Haley N Cartwright, Dominique J Barbeau, Anita K McElroy

Journal: mSphere

PubMed ID: 34494884

Doi: 10.1128/mSphere.00556-21

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Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition

Authors: Chelsie A Kadgien, Anusha Kamesh, Austen J Milnerwood

Journal: Mol Brain

PubMed ID: 34530877

Doi: 10.1186/s13041-021-00848-w

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Next-Generation Sequencing Reveals Four Novel Viruses Associated with Calf Diarrhea

Authors: Qi Wu, Jizong Li, Wei Wang, Jinzhu Zhou, Dandan Wang, Baochao Fan, Xuehan Zhang, Dongbo Sun, Ga Gong, Sizhu Suolang, Bin Li

Journal: Viruses

PubMed ID: 34696337

Doi: 10.3390/v13101907

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Humoral and cellular immune response and safety of two-dose SARS-CoV-2 mRNA-1273 vaccine in solid organ transplant recipients

Authors: Victoria G Hall, Victor H Ferreira, Matthew Ierullo, Terrance Ku, Tina Marinelli, Beata Majchrzak-Kita, Anila Yousuf, Vathany Kulasingam, Atul Humar, Deepali Kumar

Journal: Am J Transplant

PubMed ID: 34347934

Doi: 10.1111/ajt.16766

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-Specific T Cell Functional, Memory, and Activation Profiles in QuantiFERON-Reverters Are Consistent With Controlled Infection

Authors: Cheleka A M Mpande, Pia Steigler, Tessa Lloyd, Virginie Rozot, Boitumelo Mosito, Constance Schreuder, Timothy D Reid, Nicole Bilek, Morten Ruhwald, Jason R Andrews, Mark Hatherill, Francesca Little, Thomas J Scriba, Elisa Nemes

Journal: Front Immunol

PubMed ID: 34526988

Doi: 10.3389/fimmu.2021.712480

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Extremely short bioavailability and fast pharmacodynamic effects of pMHC-based nanomedicines

Authors: Yang Yang, Kristofor K Ellestad, Santiswarup Singha, Muhammad Myn Uddin, Robert Clarke, Debajyoti Mondal, Nahir Garabatos, Patricia Solé, Cesar Fandos, Pau Serra, Pere Santamaria

Journal: J Control Release

PubMed ID: 34474072

Doi: 10.1016/j.jconrel.2021.08.043

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