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GPCR activation and GRK2 assembly by a biased intracellular agonist

Authors: Jia Duan , Heng Liu , Fenghui Zhao , Qingning Yuan , Yujie Ji , Xiaoqing Cai , Xinheng He , Xinzhu Li , Junrui Li , Kai Wu , Tianyu Gao , Shengnan Zhu , Shi Lin , Ming-Wei Wang , Xi Cheng , Wanchao Yin , Yi Jiang , Dehua Yang , H Eric Xu

Journal: Nature .

PubMed ID: 37532940

Doi: 10.1038/s41586-023-06395-9

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1

Authors: Jonathan F Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L Gloor, Samantha Rustichelli, Victoria Godínez-López, Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan Gretarsson, Jonathan M Burg, Allison R Hickman, Lu Sun, Saarang Gopinath, Hailey F Taylor, Zu-Wen Sun, Ryan J Ezell, Anup Vaidya, Matthew J Meiners, Marcus A Cheek, William J Rice, Vladimir Svetlov, Evgeny Nudler, Chao Lu, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache

Journal: Sci Adv

PubMed ID: 37556531

Doi: 10.1126/sciadv.adg9832

Products & Services: Proteins, Expression, Isolation and Analysis

Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting

Authors: Stefania Torino, Mugdha Dhurandhar, Annelore Stroobants, Raf Claessens, Rouslan G Efremov

Journal: Nat Methods

PubMed ID: 37592181

Doi: 10.1038/s41592-023-01967-z

Products & Services: Proteins, Expression, Isolation and Analysis

Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells

Authors: Sergio P Alpuche-Lazcano, Matthew Stuible, Bassel Akache, Anh Tran, John Kelly, Sabahudin Hrapovic, Anna Robotham, Arsalan Haqqani, Alexandra Star, Tyler M Renner, Julie Blouin, Jean-Sébastien Maltais, Brian Cass, Kai Cui, Jae-Young Cho, Xinyu Wang, Daria Zoubchenok, Renu Dudani, Diana Duque, Michael J McCluskie, Yves Durocher

Journal: Commun Med (Lond)

PubMed ID: 37612423

Doi: 10.1038/s43856-023-00340-7

Products & Services: Proteins, Expression, Isolation and Analysis

High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase

Authors: Lu Yang, Tristan Wagner, Ariel Mechaly, Alexandra Boyko, Eduardo M Bruch, Daniela Megrian, Francesca Gubellini, Pedro M Alzari, Marco Bellinzoni

Journal: Nat Commun

PubMed ID: 37563123

Doi: 10.1038/s41467-023-40253-6

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of sucrose synthase from to favor biocatalytic glycosylation

Authors: Kai Chen, Lei Lin, Ruiqi Ma, Jiajie Ding, Huayi Pan, Yehui Tao, Yan Li, Honghua Jia

Journal: Front Microbiol

PubMed ID: 37649634

Doi: 10.3389/fmicb.2023.1220208

Products & Services: Proteins, Expression, Isolation and Analysis

Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation

Authors: Frederic Morales-Paytuví, Alba Fajardo, Carles Ruiz-Mirapeix, James Rae, Francesc Tebar, Marta Bosch, Carlos Enrich, Brett M Collins, Robert G Parton, Albert Pol

Journal: J Cell Biol

PubMed ID: 37526691

Doi: 10.1083/jcb.202204020

Products & Services: Proteins, Expression, Isolation and Analysis

Anti-SARS-CoV-2 Antibody Level Is Associated with a History of COVID-19 Infection and mRNA Vaccination in Patients with Diabetes

Authors: Is Asma'ul Haq Hataul, Nanny Natalia M Soetedjo, Josephine Debora, Marita Restie Tiara, Hofiya Djauhari, Evan Susandi, Bachti Alisjahbana, Rudi Wisaksana, Hikmat Permana

Journal: Vaccines (Basel)

PubMed ID: 37766101

Doi: 10.3390/vaccines11091424

Products & Services: Proteins, Expression, Isolation and Analysis

Interchangeability of the Assays Used to Assess the Activity of Anti-SARS-CoV-2 Monoclonal Antibodies

Authors: Brady T Hickerson, Alexey M Khalenkov, Tao Xie, David M Frucht, Dorothy E Scott, Natalia A Ilyushina

Journal: Viruses

PubMed ID: 37632039

Doi: 10.3390/v15081698

Products & Services: Proteins, Expression, Isolation and Analysis

Gene co-option, duplication and divergence of cement proteins underpin the evolution of bioadhesives across barnacle life histories

Authors: Yue Him Wong, Niklas Dreyer, HaoCheng Liu, Yi Lan, Jamie J Chen, Jin Sun, Wei-Peng Zhang, Pei-Yuan Qian, Benny K K Chan