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Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing

Authors: Xi He, Shuo Quan, Min Xu, Silveria Rodriguez, Shih Lin Goh, Jiajie Wei, Arthur Fridman, Kenneth A Koeplinger, Steve S Carroll, Jay A Grobler, Amy S Espeseth, David B Olsen, Daria J Hazuda, Dai Wang

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33766889

Doi: 10.1073/pnas.2025866118

Products & Services: Proteins, Expression, Isolation and Analysis

A calcineurin-mediated scaling mechanism that controls a K-leak channel to regulate morphogen and growth factor transcription

Authors: Chao Yi, Tim Wgm Spitters, Ezz Al-Din Ahmed Al-Far, Sen Wang, TianLong Xiong, Simian Cai, Xin Yan, Kaomei Guan, Michael Wagner, Ali El-Armouche, Christopher L Antos

Journal: Elife

PubMed ID: 33830014

Doi: 10.7554/eLife.60691

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

Authors: Marco Mandolesi, Daniel J Sheward, Leo Hanke, Junjie Ma, Pradeepa Pushparaj, Laura Perez Vidakovics, Changil Kim, Monika Àdori, Klara Lenart, Karin Loré, Xaquin Castro Dopico, Jonathan M Coquet, Gerald M McInerney, Gunilla B Karlsson Hedestam, Ben Murrell

Journal: Cell Rep Med

PubMed ID: 33842900

Doi: 10.1016/j.xcrm.2021.100252

Products & Services: Proteins, Expression, Isolation and Analysis

A Rationally Designed Bovine IgA Fc Scaffold Enhances Accumulation of a VH-Fc Fusion Without Compromising Binding to Enterohemorrhagic

Authors: Adam Chin-Fatt, Reza Saberianfar, Rima Menassa

Journal: Front Plant Sci

PubMed ID: 33936135

Doi: 10.3389/fpls.2021.651262

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of a novel promoter for driving antibiotic-resistant genes to reduce the metabolic burden during protein expression and effectively select multiple integrations in Pichia Pastoris

Authors: Qi Shen, Zhuang Yu, Xiao-Ting Zhou, Shi-Jia Zhang, Shu-Ping Zou, Neng Xiong, Ya-Ping Xue, Zhi-Qiang Liu, Yu-Guo Zheng

Journal: Appl Microbiol Biotechnol

PubMed ID: 33818673

Doi: 10.1007/s00253-021-11195-0

Products & Services: Proteins, Expression, Isolation and Analysis

Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis

Authors: Hudie Wei, Lingzhi Qu, Shuyan Dai, Yun Li, Haolan Wang, Yilu Feng, Xiaojuan Chen, Longying Jiang, Ming Guo, Jun Li, Zhuchu Chen, Lin Chen, Ye Zhang, Yongheng Chen

Journal: Nat Commun

PubMed ID: 33863900

Doi: 10.1038/s41467-021-22655-6

Products & Services: Proteins, Expression, Isolation and Analysis

Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan

Authors: Shenglong Ling , Pan Shi , Sanling Liu , Xianyu Meng , Yingxin Zhou , Wenjing Sun , Shenghai Chang , Xing Zhang , Longhua Zhang , Chaowei Shi , Demeng Sun , Lei Liu , Changlin Tian

Journal: Cell Res

PubMed ID: 33603117

Doi: 10.1038/s41422-021-00474-0

Products & Services: Proteins, Expression, Isolation and Analysis

Clinical Strains of With Strong Cell Invasiveness and the Protective Effect of Patchouli Alcohol by Improving miR-30b/C Mediated Xenophagy

Authors: Yifei Xu, Qiuhua Deng, Yuanzun Zhong, Li Jing, Haiwen Li, Jingwei Li, Huimin Yu, Huafeng Pan, Shaoju Guo, Hongying Cao, Ping Huang, Bin Huang

Journal: Front Pharmacol

PubMed ID: 33995095

Doi: 10.3389/fphar.2021.666903

Products & Services: Proteins, Expression, Isolation and Analysis

Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases

Authors: Anne V Lyngstadaas, Markus V Olsen, Jeffrey A Bair, Robin R Hodges, Tor P Utheim, Charles N Serhan, Darlene A Dartt

Journal: Front Immunol

PubMed ID: 33968020

Doi: 10.3389/fimmu.2021.618653

Products & Services: Proteins, Expression, Isolation and Analysis

Traumatic Optic Neuropathy Is Associated with Visual Impairment, Neurodegeneration, and Endoplasmic Reticulum Stress in Adolescent Mice

Authors: Shelby M Hetzer, Fernanda Guilhaume-Correa, Dylan Day, Alicia Bedolla, Nathan K Evanson