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Design and Evaluation of a Humanized Anti-EGFR huscFv Antibody Fragment in Combination With Metformin in A549 Cells

Authors: Jorge Solis-Estrada, Eder Arredondo-Espinoza, Elizeth Pioquinto-Ávila, Aldo O González-Cruz, Xristo Zarate, Isaías Balderas-Rentería

Journal: Anticancer Res

PubMed ID: 38677771

Doi: 10.21873/anticanres.16998

Products & Services: Proteins, Expression, Isolation and Analysis

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice

Authors: Laiqiang Chen, Yiyang Qin, Tingting Guo, Wenzhen Zhu, Jingpan Lin, Tingting Xing, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Xiang Li, Peng Yin, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: Cell Death Dis

PubMed ID: 38744826

Doi: 10.1038/s41419-024-06716-4

Products & Services: Proteins, Expression, Isolation and Analysis

A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction

Authors: Baiyang Sun, Zihe Liang, Yupeng Wang, Yue Yu, Xiaobing Zhou, Xingchao Geng, Bo Li

Journal: Toxicology

PubMed ID: 38740170

Doi: 10.1016/j.tox.2024.153829

Products & Services: Proteins, Expression, Isolation and Analysis

TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease

Authors: Yiyang Qin, Laiqiang Chen, Wenzhen Zhu, Jiahong Song, Jingpan Lin, Yuwei Li, Jiawei Zhang, Xichen Song, Tingting Xing, Tingting Guo, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Qi Wang, Bang Li, Weili Yang , Peng Yin, Xiao-Xin Yan, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: SCIENCE ADVANCES

PubMed ID: 38758800

Doi: 10.1126/sciadv.adl2036

Products & Services: Proteins, Expression, Isolation and Analysis

Quercetin induces itaconic acid-mediated M1/M2 alveolar macrophages polarization in respiratory syncytial virus infection

Authors: Li An , Qianwen Zhai , Keyu Tao , Yingcai Xiong , Weiying Ou , Ziwei Yu , Xingyu Yang , Jianjian Ji , Mengjiang Lu

Journal: Phytomedicine

PubMed ID: 38797031

Doi: 10.1016/j.phymed.2024.155761

Products & Services: Proteins, Expression, Isolation and Analysis

A fluorescence anisotropy-based competition assay to identify inhibitors against ricin and Shiga toxin ribosome interactions

Authors: Arkajyoti Dutta, Zoltan Szekely, Hakan Guven, Xiao-Ping Li, John E McLaughlin, Nilgun E Tumer

Journal: Anal Biochem

PubMed ID: 38825159

Doi: 10.1016/j.ab.2024.115580

Products & Services: Proteins, Expression, Isolation and Analysis

A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2

Authors: Yashavantha L Vishweshwaraiah, Brianna Hnath, Jian Wang, Morgan Chandler, Arnab Mukherjee, Neela H Yennawar, Squire J Booker, Kirill A Afonin, Nikolay V Dokholyan

Journal: ACS Appl Bio Mater

PubMed ID: 38700999

Doi: 10.1021/acsabm.4c00222

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of Fibrinogen as a Plasma Protein Binding Partner for Lecanemab Biosimilar IgG: Implications for Alzheimer's Disease Therapy

Authors: Jean-Pierre Bellier, Andrea Roman, Caitlyn Christiano, Juliana Au Anzai, Stephanie Moreno, Emily C Campbell, Lucas Godwin, Amy Li, Alan Chen, Sarah M Alan, Adriana Saba, Han Bin Yoo, Hyun-Sik Yang, Jasmeer P Chhatwal, Dennis J Selkoe, Lei Liu

Journal: biorxiv

PubMed ID: 38746192

Doi: 10.1101/2024.05.01.591892

Products & Services: Proteins, Expression, Isolation and Analysis

The pioneer transcription factor Zelda facilitates the exit from regeneration and restoration of patterning in

Authors: Anish Bose, Keaton Schuster, Chandril Kodali, Surabhi Sonam, Rachel Smith-Bolton

Journal: biorxiv

PubMed ID: 38854062

Doi: 10.1101/2024.05.30.596672

Products & Services: Proteins, Expression, Isolation and Analysis

A vector system for single and tandem expression of cloned genes and multi-colour fluorescent tagging in

Authors: Solenne Ithurbide, Roshali T de Silva, Hannah J Brown, Vinaya Shinde, Iain G Duggin