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Monoallelic loss-of-function THPO variants cause heritable thrombocytopenia

Authors: Cornish N,Aungraheeta MR,FitzGibbon L,Burley K,Alibhai D,Collins J,Greene D,Downes K,NIHR BioResource.,Westbury SK,Turro E,Mumford AD

Journal: Blood advances

PubMed ID: 32150607

Doi: 10.1182/bloodadvances.2019001293

Products & Services: Recombinant Proteins

Routes of iron entry into, and exit from, the catalytic ferroxidase sites of the prokaryotic ferritin SynFtn

Authors: Bradley JM,Pullin J,Moore GR,Svistunenko DA,Hemmings AM,Le Brun NE

Journal: Dalton transactions (Cambridge, England : 2003)

PubMed ID: 31930254

Doi: 10.1039/c9dt03570b

Products & Services: Recombinant Proteins

Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes

Authors: Shinohara M,Tashiro Y,Shinohara M,Hirokawa J,Suzuki K,Onishi-Takeya M,Mukouzono M,Takeda S,Saito T,Fukumori A,Saido TC,Morishita R,Sato N

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology

PubMed ID: 31907998

Doi: 10.1096/fj.201901028RR

Products & Services: Recombinant Proteins

Kaposi's Sarcoma-Associated Herpesvirus Viral Interleukin-6 Signaling Upregulates Integrin β3 Levels and Is Dependent on STAT3

Authors: Rivera-Soto R,Dissinger NJ,Damania B

Journal: Journal of Virology

PubMed ID: 31801855

Doi: 10.1128/JVI.01384-19

Products & Services: Recombinant Proteins

Spatiotemporal neocartilage growth in matrix-metalloproteinase-sensitive poly(ethylene glycol) hydrogels under dynamic compressive loading: an experimental and computational approach

Authors: Schneider MC, Lalitha Sridhar S, Vernerey FJ, Bryant SJ.

Journal: J Mater Chem B

PubMed ID: 32155233

Doi: 10.1039/c9tb02963j

Products & Services: Recombinant Proteins

Discovery and characterization of single-domain antibodies for polymeric Ig receptor-mediated mucosal delivery of biologics

Authors: Maruthachalam BV, Zwolak A, Lin-Schmidt X, Keough E, Tamot N, Venkataramani S, Geist B, Singh S, Ganesan R.

Journal: MAbs

PubMed ID: 31906797

Doi: 10.1080/19420862.2019.1708030

Products & Services: Recombinant Proteins

Investigation of inactive state κ opioid receptor homodimerization via single molecule microscopy using new antagonistic fluorescent probes

Authors: Drakopoulos A, Koszegi Z, Lanoiselée Y, Hübner H, Gmeiner P, Calebiro D, Decker M.

Journal: J Med Chem

PubMed ID: 32159953

Doi: 10.1021/acs.jmedchem.9b02011

Products & Services: Recombinant Proteins

Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation

Authors: Misawa T, SoRelle JA, Choi JH, Yue T, Wang KW, McAlpine W, Wang J, Liu A, Tabeta K, Turer EE, Evers B, Nair-Gill E, Poddar S, Su L, Ou F, Yu L, Russell J, Ludwig S, Zhan X, Hildebrand S, Li X, Tang M, Murray AR, Moresco EMY, Beutler B.

Journal: Sci Immunol

PubMed ID: 31980486

Doi: 10.1126/sciimmunol.aaz0085

Products & Services: Recombinant Proteins

CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model

Authors: Brooks P, Zur Bruegge T, Boyle EC, Kalies S, Villarreal SN, Liese A, Bleich A, Buettner M.

Journal: Stem Cells Int

PubMed ID: 32076438

Doi: 10.1155/2020/4069354

Products & Services: Recombinant Proteins

The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia

Authors: Machado MG, Tavares LP, Souza GVS, Queiroz-Junior CM, Ascenção FR, Lopes ME, Garcia CC, Menezes GB, Perretti M, Russo RC, Teixeira MM, Sousa LP, .

Journal: FASEB J

PubMed ID: 31908042

Doi: 10.1096/fj.201902172R

Products & Services: Recombinant Proteins