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Low-dose rAAV-mediated inhibition of VEGF can treat neovascular pathologies without inducing retinal vasculitis

Authors: Shun-Yun Cheng, Yongwen Luo, Anneliese Malachi, Jihye Ko, Qin Su, Jun Xie, Bo Tian, Haijiang Lin, Xiao Ke, Qiang Zheng, Phillip W L Tai, Guangping Gao, Claudio Punzo

Journal: Hum Gene Ther

PubMed ID: 34182803

Doi: 10.1089/hum.2021.132

Products & Services: Recombinant Proteins

Investigation of the mechanisms of VEGF-mediated compensatory lung growth: the role of the VEGF heparin-binding domain

Authors: Lumeng J Yu, Victoria H Ko, Duy T Dao, Jordan D Secor, Amy Pan, Bennet S Cho, Paul D Mitchell, Hiroko Kishikawa, Diane R Bielenberg, Mark Puder

Journal: Sci Rep

PubMed ID: 34088930

Doi: 10.1038/s41598-021-91127-0

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Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity

Authors: Lise Chauveau, Anne Bridgeman, Tiong K Tan, Ryan Beveridge, Joe N Frost, Pramila Rijal, Isabela Pedroza-Pacheco, Thomas Partridge, Javier Gilbert-Jaramillo, Michael L Knight, Xu Liu, Rebecca A Russell, Persephone Borrow, Hal Drakesmith, Alain R Townsend, Jan Rehwinkel

Journal: EMBO Rep

PubMed ID: 34142428

Doi: 10.15252/embr.202152447

Products & Services: Recombinant Proteins

Exosomes from bovine endometrial epithelial cells ensure trophoblast cell development by miR-218 targeting secreted frizzled related protein 2

Authors: Wang X,Li Q,Xie T,Yuan M,Sheng X,Qi X,Xing K,Liu F,Guo Y,Xiao L,Ni H

Journal: Journal of cellular physiology

PubMed ID: 33230823

Doi: 10.1002/jcp.30180

Products & Services: Recombinant Proteins

Long non-coding RNA THRIL is upregulated in coronary heart disease and binds to microRNA-424 to upregulate TXNIP in mice

Authors: Lin Lin, Jinli Bao

Journal: Microvasc Res

PubMed ID: 34171363

Doi: 10.1016/j.mvr.2021.104215

Products & Services: Recombinant Proteins

Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF-κB signaling

Authors: Yingzi Zhao, Fang Zong

Journal: Immun Inflamm Dis

PubMed ID: 34089575

Doi: 10.1002/iid3.465

Products & Services: Recombinant Proteins

Design and Study of PEG Linkers That Enable Robust Characterization of PEGylated Proteins

Authors: Anumita Saha-Shah, Shuwen Sun, John Kong, Wendy Zhong, Benjamin F Mann

Journal: ACS Pharmacol Transl Sci

PubMed ID: 34423265

Doi: 10.1021/acsptsci.1c00112

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Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family

Authors: Kaitlin N Hart, William A Stocker, Nicholas G Nagykery, Kelly L Walton, Craig A Harrison, Patricia K Donahoe, David Pépin, Thomas B Thompson

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34155118

Doi: 10.1073/pnas.2104809118

Products & Services: Recombinant Proteins

Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation

Authors: Mujtaba Hassan, Sjors van Klaveren, Maria Håkansson, Carl Diehl, Rebeka Kovačič, Floriane Baussière, Anders P Sundin, Jaka Dernovšek, Björn Walse, Fredrik Zetterberg, Hakon Leffler, Marko Anderluh, Tihomir Tomašič, Žiga Jakopin, Ulf J Nilsson

Journal: Eur J Med Chem

PubMed ID: 34225180

Doi: 10.1016/j.ejmech.2021.113664

Products & Services: Recombinant Proteins

Activating the Cpx response induces tolerance to antisense PNA delivered by an arginine-rich peptide in

Authors: Jakob Frimodt-Møller, Andreas Koulouktsis, Godefroid Charbon, Marit Otterlei, Peter E Nielsen, Anders Løbner-Olesen

Journal: Mol Ther Nucleic Acids

PubMed ID: 34484867

Doi: 10.1016/j.omtn.2021.06.009

Products & Services: Recombinant Proteins