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The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins.

Authors: Neal Sonya，Jaeger Philipp A，Duttke Sascha H，Benner Christopher，K Glass Christopher，Ideker Trey，Hampton Randol

Journal: Mol. Cell

PubMed ID: 29351849

Doi: 10.1016/j.molcel.2017.12.012

Products & Services: Recombinant Proteins

TRPC5 Does Not Cause or Aggravate Glomerular Disease.

Authors: Wang Xuexiang，Dande Ranadheer R，Yu Hao，Samelko Beata，Miller Rachel E，Altintas Mehmet M，Reiser Jo

Journal: J. Am. Soc. Nephrol.

PubMed ID: 29061651

Doi: 10.1681/ASN.2017060682

Products & Services: Recombinant Proteins

Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization.

Authors: Jiang Mei，Liu Xinghui，Zhang Denghai，Wang Ying，Hu Xiaoxia，Xu Fengxia，Jin Mingming，Cao Fanfan，Xu L

Journal: J Neuroinflammation

PubMed ID: 29540209

Doi: 10.1186/s12974-018-1124-6

Products & Services: Recombinant Proteins

Brain Shuttle Antibody for Alzheimer's Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode.

Authors: Weber Felix，Bohrmann Bernd，Niewoehner Jens，Fischer Jens A A，Rueger Petra，Tiefenthaler Georg，Moelleken Joerg，Bujotzek Alexander，Brady Kevin，Singer Thomas，Ebeling Martin，Iglesias Antonio，Freskg?rd Per

Journal: Cell Rep

PubMed ID: 29298417

Doi: 10.1016/j.celrep.2017.12.019

Products & Services: Recombinant Proteins

MultiBacMam Bimolecular Fluorescence Complementation (BiFC) tool-kit identifies new small-molecule inhibitors of the CDK5-p25 protein-protein interaction (PPI).

Authors: Bellón-Echeverría Itxaso，Carralot Jean-Philippe，Del Rosario Andrea Araujo，Kueng Stephanie，Mauser Harald，Schmid Georg，Thoma Ralf，Berger

Journal: Sci Rep

PubMed ID: 29572554

Doi: 10.1038/s41598-018-23516-x

Products & Services: Recombinant Proteins

The group VIA calcium-independent phospholipase A and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts.

Authors: Kuwata Hiroshi，Yuzurihara Chihiro，Kinoshita Natsumi，Taki Yuki，Ikegami Yuki，Washio Sana，Hirakawa Yushi，Yoda Emiko，Aiuchi Toshihiro，Itabe Hiroyuki，Nakatani Yoshihito，Hara Shun

Journal: FEBS J.

PubMed ID: 29637744

Doi: 10.1111/febs.14462

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Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reduction.

Authors: C?té Isabelle，Green Sara M，Morgan Drake，Carter Christy S，Tümer Nihal，Scarpace Phil

Journal: Can. J. Physiol. Pharmacol.

PubMed ID: 29131966

Doi: 10.1139/cjpp-2017-0440

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The in vitro effects of macrophages on the osteogenic capabilities of MC3T3-E1 cells encapsulated in a biomimetic poly(ethylene glycol) hydrogel.

Authors: Saleh Leila S，Carles-Carner Maria，Bryant Stephan

Journal: Acta Biomater

PubMed ID: 29505890

Doi: 10.1016/j.actbio.2018.02.026

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Regional Delivery of Chimeric Antigen Receptor-Engineered T Cells Effectively Targets HER2 Breast Cancer Metastasis to the Brain.

Authors: Priceman Saul J，Tilakawardane Dileshni，Jeang Brook，Aguilar Brenda，Murad John P，Park Anthony K，Chang Wen-Chung，Ostberg Julie R，Neman Josh，Jandial Rahul，Portnow Jana，Forman Stephen J，Brown Christi

Journal: Clin. Cancer Res.

PubMed ID: 29061641

Doi: 10.1158/1078-0432.CCR-17-2041

Products & Services: Recombinant Proteins

Co-modulation of synapses and voltage-gated ionic currents by combined actions of multiple neuromodulators follow distinct rules

Authors: Xinping Li, Dirk Bucher, Farzan Nadim

Journal: biorxiv

Doi: 10.1101/265694

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